CRBU vs. VB
CRBU (Caribou Biosciences, Inc.) is a stock, while VB (Vanguard Small-Cap ETF) is Small Cap Blend Equities fund tracking the CRSP US Small Cap Index. Over the past 3 years, CRBU returned -27.26%/yr vs 17.63%/yr for VB. At a 0.47 correlation, their price movements are largely independent.
Performance
CRBU vs. VB - Performance Comparison
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Returns By Period
In the year-to-date period, CRBU achieves a -1.26% return, which is significantly lower than VB's 16.59% return.
CRBU
- 1D
- -5.42%
- 1M
- -27.31%
- YTD
- -1.26%
- 6M
- -8.72%
- 1Y
- 10.56%
- 3Y*
- -27.26%
- 5Y*
- —
- 10Y*
- —
VB
- 1D
- 0.80%
- 1M
- 2.29%
- YTD
- 16.59%
- 6M
- 14.23%
- 1Y
- 29.94%
- 3Y*
- 17.63%
- 5Y*
- 7.20%
- 10Y*
- 12.23%
CRBU vs. VB - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
CRBU Caribou Biosciences, Inc. | -1.26% | 0.00% | -72.25% | -8.76% | -58.38% | -14.50% |
VB Vanguard Small-Cap ETF | 16.59% | 8.87% | 14.17% | 18.22% | -17.51% | 4.07% |
Correlation
The correlation between CRBU and VB is 0.45, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.45 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.47 |
Correlation (All Time) Calculated using the full available price history since Jul 23, 2021 | 0.47 |
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Return for Risk
CRBU vs. VB — Risk / Return Rank
CRBU
VB
CRBU vs. VB - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Caribou Biosciences, Inc. (CRBU) and Vanguard Small-Cap ETF (VB). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| CRBU | VB | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.68 | ||
| Sortino ratioReturn per unit of downside risk | -1.76 | ||
| Omega ratioGain probability vs. loss probability | 1.09 | 1.31 | -0.22 |
| Calmar ratioReturn relative to maximum drawdown | 0.21 | 3.35 | -3.14 |
| Martin ratioReturn relative to average drawdown | 0.35 | 12.29 | -11.94 |
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Drawdowns
CRBU vs. VB - Drawdown Comparison
The maximum CRBU drawdown since its inception was -97.58%, which is greater than VB's maximum drawdown of -59.56%. Use the drawdown chart below to compare losses from any high point for CRBU and VB.
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Drawdown Indicators
| CRBU | VB | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.58% | -59.56% | -38.02% |
Max Drawdown (1Y)Largest decline over 1 year | -51.06% | -8.98% | -42.08% |
Max Drawdown (3Y)Largest decline over 3 years | -91.12% | -25.36% | -65.76% |
Max Drawdown (5Y)Largest decline over 5 years | — | -28.15% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -42.05% | — |
Current DrawdownCurrent decline from peak | -94.82% | 0.00% | -94.82% |
Average DrawdownAverage peak-to-trough decline | -79.42% | -8.42% | -71.00% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 30.38% | 2.44% | +27.94% |
Volatility
CRBU vs. VB - Volatility Comparison
Caribou Biosciences, Inc. (CRBU) has a higher volatility of 22.31% compared to Vanguard Small-Cap ETF (VB) at 4.86%. This indicates that CRBU's price experiences larger fluctuations and is considered to be riskier than VB based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| CRBU | VB | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 22.31% | 4.86% | +17.45% |
Volatility (6M)Calculated over the trailing 6-month period | 50.17% | 12.21% | +37.96% |
Volatility (1Y)Calculated over the trailing 1-year period | 81.46% | 16.63% | +64.83% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 86.59% | 20.78% | +65.81% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 86.59% | 21.42% | +65.17% |
Dividends
CRBU vs. VB - Dividend Comparison
CRBU has not paid dividends to shareholders, while VB's dividend yield for the trailing twelve months is around 1.17%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
CRBU Caribou Biosciences, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
VB Vanguard Small-Cap ETF | 1.17% | 1.33% | 1.30% | 1.55% | 1.59% | 1.24% | 1.14% | 1.39% | 1.67% | 1.35% | 1.50% | 1.48% |
Frequently Asked Questions
CRBU and VB have a correlation of 0.45, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
CRBU has higher volatility (22.31%) compared to VB (4.86%). In terms of maximum drawdown, CRBU dropped -97.58% vs VB's -59.56%.
VB currently has the higher Sharpe Ratio (1.81 vs 0.13), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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