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ISIN
US1420381089
CUSIP
142038108
IPO Date
Jul 23, 2021

Highlights

Market Cap
$157.21M
Enterprise Value
$173.39M
EPS (TTM)
-$1.41
Total Revenue (TTM)
$8.81M
Gross Profit (TTM)
$7.49M
EBITDA (TTM)
-$115.23M
Year Range
$1.22 - $3.54
Target Price
$5.00
ROA (TTM)
-89.41%
ROE (TTM)
-130.58%

Share Price Chart


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Compare stocks, funds, or ETFs

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Performance

CRBU Performance Chart

Caribou Biosciences, Inc. (CRBU) is up 3.1% since the beginning of the year. At $2 per share, CRBU is trading 53.6% below its 52-week high of $4.


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S&P 500 Index

Returns By Period

Caribou Biosciences, Inc. (CRBU) has returned 3.14% so far this year and 22.39% over the past 12 months.


Caribou Biosciences, Inc.

1D
0.00%
1M
-21.90%
YTD
3.14%
6M
-4.65%
1Y
22.39%
3Y*
-27.65%
5Y*
10Y*

Benchmark (S&P 500 Index)

1D
-0.37%
1M
-0.01%
YTD
9.16%
6M
8.64%
1Y
25.22%
3Y*
19.78%
5Y*
11.99%
10Y*
13.88%
*Multi-year figures are annualized to reflect compound growth (CAGR)

CRBU Monthly Returns History

Based on dividend-adjusted daily data since Jul 23, 2021, CRBU's average daily return is -0.04%, while the average monthly return is -0.80%.

Historically, 35% of months were positive and 65% were negative. The best month was Jul 2023 with a return of +69.2%, while the worst month was Jun 2024 at -43.1%. The longest winning streak lasted 3 consecutive months, and the longest losing streak was 8 months.

On a daily basis, CRBU closed higher 45% of trading days. The best single day was Jul 6, 2023 with a return of +45.6%, while the worst single day was Mar 12, 2024 at -30.5%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-11.32%34.75%-0.00%-1.05%25.53%-30.51%3.14%
2025-10.06%-18.18%-21.96%-6.81%24.57%18.87%61.11%-7.88%24.60%3.86%-19.83%-18.04%0.00%
20246.98%29.04%-35.02%-29.38%-20.66%-43.06%41.46%-6.90%-9.26%0.00%11.73%-27.40%-72.25%
202314.81%-15.53%-12.81%-19.02%2.56%-3.63%69.18%-18.08%-18.85%-24.06%61.71%-2.39%-8.76%
2022-28.89%-6.99%-8.02%-19.39%12.57%-34.81%49.54%21.55%6.89%-7.68%-4.41%-32.55%-58.38%
2021-8.22%67.90%-12.24%-7.37%-15.92%-18.83%-14.50%

Benchmark Metrics

Caribou Biosciences, Inc. has an annualized alpha of -29.18%, beta of 1.86, and R2 of 0.13 versus S&P 500 Index. Calculated based on daily prices since July 23, 2021.

  • This stock participated in 234.95% of S&P 500 Index downside but only 100.67% of its upside - more exposed to losses than it benefited from rallies.
  • R2 of 0.13 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
-29.18%
Beta
1.86
0.13
Upside Capture
100.67%
Downside Capture
234.95%

Return for Risk

Risk / Return Rank

CRBU ranks 53 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


CRBU Risk / Return Rank: 5353
Overall Rank
CRBU Sharpe Ratio Rank: 5252
Sharpe Ratio Rank
CRBU Sortino Ratio Rank: 5555
Sortino Ratio Rank
CRBU Omega Ratio Rank: 5252
Omega Ratio Rank
CRBU Calmar Ratio Rank: 5252
Calmar Ratio Rank
CRBU Martin Ratio Rank: 5151
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Caribou Biosciences, Inc. (CRBU) and compare them to S&P 500 Index.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


CRBUBenchmarkDifference
Sharpe ratioReturn per unit of total volatility

-1.75

Sortino ratioReturn per unit of downside risk

-1.74

Omega ratioGain probability vs. loss probability

1.11

1.37

-0.25

Calmar ratioReturn relative to maximum drawdown

0.44

2.78

-2.34

Martin ratioReturn relative to average drawdown

0.75

12.44

-11.69

Dividends

Dividend History


Caribou Biosciences, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Caribou Biosciences, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Caribou Biosciences, Inc. was 97.58%, occurring on Apr 16, 2025. The portfolio has not yet recovered.

The current Caribou Biosciences, Inc. drawdown is 94.59%.


Related event

Drawdown

Fall

Recovery

Underwater

2025 selloff2025
-97.58%Apr 2025
3y 7mo
4y 9moSep 2021 - now
2021 correction2021
-15.94%Aug 2021
6d4d
10dAug 2021 - Sep 2021
2021 correction2021
-15.80%Aug 2021
1d11d
12dAug 2021 - Aug 2021
2021 correction2021
-10.76%Jul 2021
5d7d
12dJul 2021 - Aug 2021

Drawdown Indicators


CRBUBenchmarkDifference

Max Drawdown

Largest peak-to-trough decline

-97.58%

-56.78%

-40.80%

Max Drawdown (1Y)

Largest decline over 1 year

-51.06%

-9.10%

-41.96%

Max Drawdown (3Y)

Largest decline over 3 years

-91.12%

-18.90%

-72.22%

Max Drawdown (5Y)

Largest decline over 5 years

-25.43%

Max Drawdown (10Y)

Largest decline over 10 years

-33.92%

Current Drawdown

Current decline from peak

-94.59%

-1.80%

-92.79%

Average Drawdown

Average peak-to-trough decline

-79.38%

-10.71%

-68.67%

Ulcer Index

Depth and duration of drawdowns from previous peaks

30.02%

2.03%

+27.99%

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Caribou Biosciences, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Caribou Biosciences, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for CRBU relative to other companies in the Biotechnology industry. Currently, CRBU has a P/S ratio of 17.5. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for CRBU in comparison with other companies in the Biotechnology industry. Currently, CRBU has a P/B value of 1.5. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items
Portfolio Analyzer

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