CRBU vs. SDGR
CRBU (Caribou Biosciences, Inc.) and SDGR (Schrodinger, Inc.) are both stocks. Both are in the Healthcare sector — CRBU in Biotechnology, SDGR in Health Information Services. Over the past 3 years, CRBU returned -27.65%/yr vs -28.90%/yr for SDGR. At a 0.48 correlation, their price movements are largely independent.
Performance
CRBU vs. SDGR - Performance Comparison
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Returns By Period
In the year-to-date period, CRBU achieves a 3.14% return, which is significantly higher than SDGR's -14.82% return.
CRBU
- 1D
- 0.00%
- 1M
- -21.90%
- YTD
- 3.14%
- 6M
- -4.65%
- 1Y
- 22.39%
- 3Y*
- -27.65%
- 5Y*
- —
- 10Y*
- —
SDGR
- 1D
- -3.36%
- 1M
- 14.51%
- YTD
- -14.82%
- 6M
- -21.45%
- 1Y
- -25.56%
- 3Y*
- -28.90%
- 5Y*
- -27.66%
- 10Y*
- —
CRBU vs. SDGR - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
CRBU Caribou Biosciences, Inc. | 3.14% | 0.00% | -72.25% | -8.76% | -58.38% | -14.50% |
SDGR Schrodinger, Inc. | -14.82% | -7.31% | -46.12% | 91.55% | -46.34% | -50.30% |
Correlation
The correlation between CRBU and SDGR is 0.40, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.40 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.44 |
Correlation (All Time) Calculated using the full available price history since Jul 23, 2021 | 0.48 |
Fundamentals
CRBU:
$157.21M
SDGR:
$1.13B
CRBU:
-$1.41
SDGR:
-$1.41
CRBU:
17.54
SDGR:
4.40
CRBU:
1.54
SDGR:
3.59
CRBU:
$8.81M
SDGR:
$254.91M
CRBU:
$7.49M
SDGR:
$141.04M
CRBU:
-$115.23M
SDGR:
-$85.22M
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Return for Risk
CRBU vs. SDGR — Risk / Return Rank
CRBU
SDGR
CRBU vs. SDGR - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Caribou Biosciences, Inc. (CRBU) and Schrodinger, Inc. (SDGR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| CRBU | SDGR | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.77 | ||
| Sortino ratioReturn per unit of downside risk | +1.47 | ||
| Omega ratioGain probability vs. loss probability | 1.11 | 0.95 | +0.17 |
| Calmar ratioReturn relative to maximum drawdown | 0.44 | -0.49 | +0.93 |
| Martin ratioReturn relative to average drawdown | 0.75 | -0.82 | +1.57 |
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Drawdowns
CRBU vs. SDGR - Drawdown Comparison
The maximum CRBU drawdown since its inception was -97.58%, which is greater than SDGR's maximum drawdown of -90.21%. Use the drawdown chart below to compare losses from any high point for CRBU and SDGR.
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Drawdown Indicators
| CRBU | SDGR | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.58% | -90.21% | -7.37% |
Max Drawdown (1Y)Largest decline over 1 year | -51.06% | -51.93% | +0.87% |
Max Drawdown (3Y)Largest decline over 3 years | -91.12% | -80.01% | -11.11% |
Max Drawdown (5Y)Largest decline over 5 years | — | -85.95% | — |
Current DrawdownCurrent decline from peak | -94.59% | -86.53% | -8.06% |
Average DrawdownAverage peak-to-trough decline | -79.38% | -64.15% | -15.23% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 30.02% | 31.22% | -1.20% |
Volatility
CRBU vs. SDGR - Volatility Comparison
Caribou Biosciences, Inc. (CRBU) has a higher volatility of 23.10% compared to Schrodinger, Inc. (SDGR) at 19.37%. This indicates that CRBU's price experiences larger fluctuations and is considered to be riskier than SDGR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| CRBU | SDGR | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 23.10% | 19.37% | +3.73% |
Volatility (6M)Calculated over the trailing 6-month period | 50.00% | 38.76% | +11.24% |
Volatility (1Y)Calculated over the trailing 1-year period | 81.71% | 51.48% | +30.23% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 86.66% | 63.41% | +23.25% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 86.66% | 69.89% | +16.77% |
Dividends
CRBU vs. SDGR - Dividend Comparison
Neither CRBU nor SDGR has paid dividends to shareholders.
Financials
CRBU vs. SDGR - Financials Comparison
This section allows you to compare key financial metrics between Caribou Biosciences, Inc. and Schrodinger, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
CRBU and SDGR have a correlation of 0.40, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
CRBU has higher volatility (23.10%) compared to SDGR (19.37%). In terms of maximum drawdown, CRBU dropped -97.58% vs SDGR's -90.21%.
CRBU currently has the higher Sharpe Ratio (0.28 vs -0.50), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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