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CNTA vs. QURE
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

CNTA vs. QURE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Centessa Pharmaceuticals Limited (CNTA) and uniQure N.V. (QURE). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, CNTA achieves a 58.74% return, which is significantly higher than QURE's 12.83% return.


CNTA

1D
0.20%
1M
0.28%
YTD
58.74%
6M
34.58%
1Y
233.05%
3Y*
104.97%
5Y*
12.71%
10Y*

QURE

1D
2.08%
1M
-2.39%
YTD
12.83%
6M
24.02%
1Y
56.34%
3Y*
11.25%
5Y*
-5.87%
10Y*
8.62%
*Multi-year figures are annualized to reflect compound growth (CAGR)

CNTA vs. QURE - Yearly Performance Comparison


2026 (YTD)20252024202320222021
CNTA
Centessa Pharmaceuticals Limited
58.74%49.31%110.43%156.77%-72.47%-48.23%
QURE
uniQure N.V.
12.83%35.50%160.86%-70.14%9.31%-40.28%

Correlation

The correlation between CNTA and QURE is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.16

Correlation (3Y)
Calculated over the trailing 3-year period

0.23

Correlation (5Y)
Calculated over the trailing 5-year period

0.25

Correlation (All Time)
Calculated using the full available price history since Jun 1, 2021

0.24

Fundamentals

EPS

CNTA:

-$1.81

QURE:

-$3.58

PS Ratio

CNTA:

354.44

QURE:

87.14

Total Revenue (TTM)

CNTA:

$15.00M

QURE:

$18.09M

Gross Profit (TTM)

CNTA:

$15.00M

QURE:

$13.42M

EBITDA (TTM)

CNTA:

-$227.27M

QURE:

-$164.53M

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Return for Risk

CNTA vs. QURE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CNTA
CNTA Risk / Return Rank: 9797
Overall Rank
CNTA Sharpe Ratio Rank: 9797
Sharpe Ratio Rank
CNTA Sortino Ratio Rank: 9898
Sortino Ratio Rank
CNTA Omega Ratio Rank: 9797
Omega Ratio Rank
CNTA Calmar Ratio Rank: 9797
Calmar Ratio Rank
CNTA Martin Ratio Rank: 9797
Martin Ratio Rank

QURE
QURE Risk / Return Rank: 6868
Overall Rank
QURE Sharpe Ratio Rank: 5050
Sharpe Ratio Rank
QURE Sortino Ratio Rank: 8888
Sortino Ratio Rank
QURE Omega Ratio Rank: 9090
Omega Ratio Rank
QURE Calmar Ratio Rank: 5757
Calmar Ratio Rank
QURE Martin Ratio Rank: 5454
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CNTA vs. QURE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Centessa Pharmaceuticals Limited (CNTA) and uniQure N.V. (QURE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


CNTAQUREDifference
Sharpe ratioReturn per unit of total volatility

+3.33

Sortino ratioReturn per unit of downside risk

+2.47

Omega ratioGain probability vs. loss probability

1.69

1.43

+0.27

Calmar ratioReturn relative to maximum drawdown

8.90

0.65

+8.25

Martin ratioReturn relative to average drawdown

24.63

1.06

+23.57

CNTA vs. QURE - Sharpe Ratio Comparison

The current CNTA Sharpe Ratio is 3.54, which is higher than the QURE Sharpe Ratio of 0.21. The chart below compares the historical Sharpe Ratios of CNTA and QURE, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Sharpe Ratios by Period


CNTAQUREDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

3.54

0.21

+3.33

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

0.18

-0.04

+0.22

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

0.07

Sharpe Ratio (All Time)

Calculated using the full available price history

0.18

0.05

+0.13

Drawdowns

CNTA vs. QURE - Drawdown Comparison

The maximum CNTA drawdown since its inception was -88.19%, smaller than the maximum QURE drawdown of -95.40%. Use the drawdown chart below to compare losses from any high point for CNTA and QURE.


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Drawdown Indicators


CNTAQUREDifference

Max Drawdown

Largest peak-to-trough decline

-88.19%

-95.40%

+7.21%

Max Drawdown (1Y)

Largest decline over 1 year

-26.38%

-87.21%

+60.83%

Max Drawdown (3Y)

Largest decline over 3 years

-43.72%

-87.21%

+43.49%

Max Drawdown (5Y)

Largest decline over 5 years

-88.19%

-90.11%

+1.92%

Max Drawdown (10Y)

Largest decline over 10 years

-95.40%

Current Drawdown

Current decline from peak

-0.50%

-67.15%

+66.65%

Average Drawdown

Average peak-to-trough decline

-51.99%

-56.58%

+4.59%

Ulcer Index

Depth and duration of drawdowns from previous peaks

9.51%

53.50%

-43.99%

Volatility

CNTA vs. QURE - Volatility Comparison

The current volatility for Centessa Pharmaceuticals Limited (CNTA) is 0.72%, while uniQure N.V. (QURE) has a volatility of 28.01%. This indicates that CNTA experiences smaller price fluctuations and is considered to be less risky than QURE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


CNTAQUREDifference

Volatility (1M)

Calculated over the trailing 1-month period

0.72%

28.01%

-27.29%

Volatility (6M)

Calculated over the trailing 6-month period

44.27%

92.44%

-48.17%

Volatility (1Y)

Calculated over the trailing 1-year period

66.48%

273.61%

-207.13%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

72.09%

154.08%

-81.99%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

72.30%

119.92%

-47.62%

Dividends

CNTA vs. QURE - Dividend Comparison

Neither CNTA nor QURE has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

CNTA vs. QURE - Financials Comparison

This section allows you to compare key financial metrics between Centessa Pharmaceuticals Limited and uniQure N.V.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00100.00M200.00M300.00M400.00M500.00M202220232024202520260
3.56M
(CNTA) Total Revenue
(QURE) Total Revenue
Values in USD except per share items

Frequently Asked Questions


CNTA and QURE have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

QURE has higher volatility (28.01%) compared to CNTA (0.72%). In terms of maximum drawdown, CNTA dropped -88.19% vs QURE's -95.40%.

CNTA currently has the higher Sharpe Ratio (3.54 vs 0.21), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for CNTA and QURE

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

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