CANC vs. SBIO
Compare and contrast key facts about Tema Oncology ETF (CANC) and ALPS Medical Breakthroughs ETF (SBIO).
CANC and SBIO are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. CANC is an actively managed fund by Tema. It was launched on Aug 14, 2023. SBIO is a passively managed fund by SS&C that tracks the performance of the S-Network Medical Breakthroughs Index. It was launched on Dec 31, 2014.
Performance
CANC vs. SBIO - Performance Comparison
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CANC vs. SBIO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
CANC Tema Oncology ETF | 6.91% | 42.92% | -5.37% | 510.51% | -85.34% | -51.82% |
SBIO ALPS Medical Breakthroughs ETF | 3.20% | 55.07% | 3.81% | 8.68% | -28.08% | -7.19% |
Returns By Period
In the year-to-date period, CANC achieves a 6.91% return, which is significantly higher than SBIO's 3.20% return.
CANC
- 1D
- 1.16%
- 1M
- -0.89%
- YTD
- 6.91%
- 6M
- 27.17%
- 1Y
- 58.38%
- 3Y*
- 140.92%
- 5Y*
- —
- 10Y*
- —
SBIO
- 1D
- 0.99%
- 1M
- 3.89%
- YTD
- 3.20%
- 6M
- 36.23%
- 1Y
- 95.78%
- 3Y*
- 26.37%
- 5Y*
- 1.76%
- 10Y*
- 9.75%
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CANC vs. SBIO - Expense Ratio Comparison
CANC has a 0.75% expense ratio, which is higher than SBIO's 0.50% expense ratio.
Return for Risk
CANC vs. SBIO — Risk / Return Rank
CANC
SBIO
CANC vs. SBIO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Tema Oncology ETF (CANC) and ALPS Medical Breakthroughs ETF (SBIO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| CANC | SBIO | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 2.17 | 2.92 | -0.75 |
Sortino ratioReturn per unit of downside risk | 2.84 | 3.57 | -0.74 |
Omega ratioGain probability vs. loss probability | 1.36 | 1.45 | -0.09 |
Calmar ratioReturn relative to maximum drawdown | 4.37 | 5.66 | -1.29 |
Martin ratioReturn relative to average drawdown | 15.21 | 19.94 | -4.73 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| CANC | SBIO | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 2.17 | 2.92 | -0.75 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | — | 0.05 | — |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.29 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.04 | 0.23 | -0.26 |
Correlation
The correlation between CANC and SBIO is 0.53, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.
Dividends
CANC vs. SBIO - Dividend Comparison
CANC's dividend yield for the trailing twelve months is around 0.05%, while SBIO has not paid dividends to shareholders.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
CANC Tema Oncology ETF | 0.05% | 0.06% | 3.00% | 0.56% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SBIO ALPS Medical Breakthroughs ETF | 0.00% | 0.00% | 3.55% | 0.22% | 0.00% | 0.00% | 0.00% | 0.04% | 2.79% | 1.77% |
Drawdowns
CANC vs. SBIO - Drawdown Comparison
The maximum CANC drawdown since its inception was -97.53%, which is greater than SBIO's maximum drawdown of -63.06%. Use the drawdown chart below to compare losses from any high point for CANC and SBIO.
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Drawdown Indicators
| CANC | SBIO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.53% | -63.06% | -34.47% |
Max Drawdown (1Y)Largest decline over 1 year | -12.40% | -15.08% | +2.68% |
Max Drawdown (5Y)Largest decline over 5 years | — | -53.67% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -63.06% | — |
Current DrawdownCurrent decline from peak | -55.68% | -13.79% | -41.89% |
Average DrawdownAverage peak-to-trough decline | -73.89% | -28.70% | -45.19% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.57% | 4.28% | -0.71% |
Volatility
CANC vs. SBIO - Volatility Comparison
The current volatility for Tema Oncology ETF (CANC) is 8.20%, while ALPS Medical Breakthroughs ETF (SBIO) has a volatility of 12.61%. This indicates that CANC experiences smaller price fluctuations and is considered to be less risky than SBIO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| CANC | SBIO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 8.20% | 12.61% | -4.41% |
Volatility (6M)Calculated over the trailing 6-month period | 16.22% | 22.09% | -5.87% |
Volatility (1Y)Calculated over the trailing 1-year period | 27.19% | 33.43% | -6.24% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 285.53% | 33.55% | +251.98% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 285.53% | 33.34% | +252.19% |