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BTC-USD vs. VRTX
Performance
Return for Risk
Drawdowns
Volatility

Performance

BTC-USD vs. VRTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Bitcoin (BTC-USD) and Vertex Pharmaceuticals Incorporated (VRTX). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, BTC-USD achieves a -26.27% return, which is significantly lower than VRTX's -1.86% return. Over the past 10 years, BTC-USD has outperformed VRTX with an annualized return of 57.23%, while VRTX has yielded a comparatively lower 17.15% annualized return.


BTC-USD

1D
1.71%
1M
-20.43%
YTD
-26.27%
6M
-28.52%
1Y
-39.20%
3Y*
36.94%
5Y*
9.74%
10Y*
57.23%

VRTX

1D
-0.03%
1M
-1.22%
YTD
-1.86%
6M
-1.57%
1Y
-2.31%
3Y*
9.16%
5Y*
18.18%
10Y*
17.15%
*Multi-year figures are annualized to reflect compound growth (CAGR)

BTC-USD vs. VRTX - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
BTC-USD
Bitcoin
-26.27%-6.27%120.76%155.82%-64.23%59.40%304.57%94.10%-73.37%1,324.24%
VRTX
Vertex Pharmaceuticals Incorporated
-1.86%12.58%-1.03%40.90%31.50%-7.08%7.94%32.13%10.58%103.42%

Correlation

The correlation between BTC-USD and VRTX is 0.12, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.12

Correlation (3Y)
Calculated over the trailing 3-year period

0.07

Correlation (5Y)
Calculated over the trailing 5-year period

0.11

Correlation (10Y)
Calculated over the trailing 10-year period

0.06

Correlation (All Time)
Calculated using the full available price history since Sep 28, 2012

0.04

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Return for Risk

BTC-USD vs. VRTX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

BTC-USD
BTC-USD Risk / Return Rank: 3434
Overall Rank
BTC-USD Sharpe Ratio Rank: 1919
Sharpe Ratio Rank
BTC-USD Sortino Ratio Rank: 3737
Sortino Ratio Rank
BTC-USD Omega Ratio Rank: 3535
Omega Ratio Rank
BTC-USD Calmar Ratio Rank: 5151
Calmar Ratio Rank
BTC-USD Martin Ratio Rank: 3030
Martin Ratio Rank

VRTX
VRTX Risk / Return Rank: 3737
Overall Rank
VRTX Sharpe Ratio Rank: 3939
Sharpe Ratio Rank
VRTX Sortino Ratio Rank: 3434
Sortino Ratio Rank
VRTX Omega Ratio Rank: 3535
Omega Ratio Rank
VRTX Calmar Ratio Rank: 3838
Calmar Ratio Rank
VRTX Martin Ratio Rank: 3737
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BTC-USD vs. VRTX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Bitcoin (BTC-USD) and Vertex Pharmaceuticals Incorporated (VRTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


BTC-USDVRTXDifference
Sharpe ratioReturn per unit of total volatility

-0.82

Sortino ratioReturn per unit of downside risk

-1.38

Omega ratioGain probability vs. loss probability

0.87

1.02

-0.15

Calmar ratioReturn relative to maximum drawdown

-0.77

-0.14

-0.63

Martin ratioReturn relative to average drawdown

-1.33

-0.29

-1.04

BTC-USD vs. VRTX - Sharpe Ratio Comparison

The current BTC-USD Sharpe Ratio is -0.92, which is lower than the VRTX Sharpe Ratio of -0.10. The chart below compares the historical Sharpe Ratios of BTC-USD and VRTX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

BTC-USD vs. VRTX - Drawdown Comparison

The maximum BTC-USD drawdown since its inception was -85.30%, smaller than the maximum VRTX drawdown of -91.77%. Use the drawdown chart below to compare losses from any high point for BTC-USD and VRTX.


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Drawdown Indicators


BTC-USDVRTXDifference

Max Drawdown

Largest peak-to-trough decline

-85.30%

-91.77%

+6.47%

Max Drawdown (1Y)

Largest decline over 1 year

-51.21%

-23.56%

-27.65%

Max Drawdown (3Y)

Largest decline over 3 years

-51.21%

-29.07%

-22.14%

Max Drawdown (5Y)

Largest decline over 5 years

-76.67%

-29.07%

-47.60%

Max Drawdown (10Y)

Largest decline over 10 years

-83.80%

-41.60%

-42.20%

Current Drawdown

Current decline from peak

-48.27%

-13.90%

-34.37%

Average Drawdown

Average peak-to-trough decline

-42.36%

-37.73%

-4.63%

Ulcer Index

Depth and duration of drawdowns from previous peaks

35.16%

11.30%

+23.86%

Volatility

BTC-USD vs. VRTX - Volatility Comparison

Bitcoin (BTC-USD) has a higher volatility of 11.97% compared to Vertex Pharmaceuticals Incorporated (VRTX) at 7.47%. This indicates that BTC-USD's price experiences larger fluctuations and is considered to be riskier than VRTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


BTC-USDVRTXDifference

Volatility (1M)

Calculated over the trailing 1-month period

11.97%

7.47%

+4.50%

Volatility (6M)

Calculated over the trailing 6-month period

34.64%

20.71%

+13.93%

Volatility (1Y)

Calculated over the trailing 1-year period

35.59%

34.13%

+1.46%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

44.57%

28.53%

+16.04%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

56.61%

32.82%

+23.79%

Frequently Asked Questions


BTC-USD and VRTX have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

BTC-USD has higher volatility (11.97%) compared to VRTX (7.47%). In terms of maximum drawdown, BTC-USD dropped -85.30% vs VRTX's -91.77%.

VRTX currently has the higher Sharpe Ratio (-0.10 vs -0.92), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for BTC-USD and VRTX

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

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