Rydex Biotechnology Fund (RYOIX) Alternatives
Rydex Biotechnology Fund (RYOIX) belongs to the Health & Biotech Equities category. Below you'll find alternative mutual funds from the same category, ranked by key criteria, plus funds that investors commonly compare with RYOIX. Use the tables to find lower-cost options, better risk-adjusted returns, or funds that fit a different role in your portfolio.
Cheapest Alternatives to RYOIX
RYOIX charges 1.36% annually. Among mutual funds in the Health & Biotech Equities category, these options have the lowest expense ratios among RYOIX alternatives.
| Symbol | Name | Expense Ratio | Inception | |
|---|---|---|---|---|
| Vanguard Health Care Index Fund Admiral Shares | 0.10% | Feb 5, 2004 | RYOIX vs VHCIX | |
| Vanguard Health Care Fund Admiral Shares | 0.25% | Nov 12, 2001 | RYOIX vs VGHAX | |
| Vanguard Health Care Fund Investor Shares | 0.30% | May 23, 1984 | RYOIX vs VGHCX | |
| Fidelity Advisor Health Care Fund Class Z | 0.59% | Oct 2, 2018 | RYOIX vs FIKCX | |
| Fidelity Advisor Biotechnology Fund Class Z | 0.61% | Oct 2, 2018 | RYOIX vs FIJYX |
Best Risk-Adjusted Alternatives to RYOIX
Among mutual funds in the Health & Biotech Equities category, these options rank highest on PortfoliosLab's risk-adjusted score, which accounts for volatility, drawdown, and return consistency over a 1-year period.
| Symbol | Name | Risk / Return Rank | Inception | |
|---|---|---|---|---|
| Franklin Biotechnology Discovery Fund | 91 | Sep 14, 1997 | RYOIX vs FBDIX | |
| Eventide Healthcare & Life Sciences Fund | 88 | Dec 26, 2012 | RYOIX vs ETIHX | |
| Fidelity Advisor Biotechnology Fund I Class | 83 | Dec 27, 2000 | RYOIX vs FBTIX | |
| Fidelity Advisor Biotechnology Fund Class Z | 83 | Oct 2, 2018 | RYOIX vs FIJYX | |
| Fidelity Advisor Biotechnology Fund Class A | 83 | Dec 27, 2000 | RYOIX vs FBTAX |
Top Performing RYOIX Alternatives (YTD)
RYOIX alternatives from the Health & Biotech Equities category, sorted by year-to-date return.
| Symbol | Name | YTD Return | Inception | |
|---|---|---|---|---|
| Saratoga Health & Biotechnology Fund | -1.13% | Jul 14, 1999 | RYOIX vs SHPAX | |
| Live Oak Health Sciences Fund | -1.53% | Jun 28, 2001 | RYOIX vs LOGSX | |
| Fidelity Select Pharmaceuticals Portfolio | -2.56% | Jun 17, 2001 | RYOIX vs FPHAX | |
| Fidelity Advisor Biotechnology Fund Class Z | -2.59% | Oct 2, 2018 | RYOIX vs FIJYX | |
| Fidelity Advisor Biotechnology Fund I Class | -2.62% | Dec 27, 2000 | RYOIX vs FBTIX |
Lowest Volatility Alternatives to RYOIX
RYOIX alternatives from the Health & Biotech Equities category, sorted by annualized volatility over the past year.
| Symbol | Name | Volatility 1Y | Inception | |
|---|---|---|---|---|
| Invesco Health Care Fund | 15.67% | Aug 6, 1989 | RYOIX vs GGHCX | |
| BlackRock Health Sciences Opportunities Portfolio | 16.30% | Dec 20, 1999 | RYOIX vs SHSAX | |
| Health Sciences Opportunities Fund Class Instituti... | 16.32% | Oct 16, 2000 | RYOIX vs SHSSX | |
| Live Oak Health Sciences Fund | 16.35% | Jun 28, 2001 | RYOIX vs LOGSX | |
| Alger Health Sciences Fund | 16.42% | Apr 30, 2002 | RYOIX vs AHSAX |
Lowest Drawdown Alternatives to RYOIX
RYOIX alternatives from the Health & Biotech Equities category, sorted by maximum drawdown over the past year.
| Symbol | Name | Max Drawdown 1Y | Inception | |
|---|---|---|---|---|
| Live Oak Health Sciences Fund | -7.65% | Jun 28, 2001 | RYOIX vs LOGSX | |
| Saratoga Health & Biotechnology Fund | -7.87% | Jul 14, 1999 | RYOIX vs SHPAX | |
| Vanguard Health Care Fund Admiral Shares | -9.19% | Nov 12, 2001 | RYOIX vs VGHAX | |
| Vanguard Health Care Fund Investor Shares | -9.20% | May 23, 1984 | RYOIX vs VGHCX | |
| AlphaCentric LifeSci Healthcare Fund | -9.47% | Nov 28, 2019 | RYOIX vs LYFIX |
Other Mutual Funds from Rydex Funds
Most popular Rydex Funds mutual funds on PortfoliosLab, across asset classes.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | Inception | |
|---|---|---|---|---|---|---|
| Rydex Monthly Rebalance NASDAQ-100 2x Strategy Fun... | Leveraged Equities, Leveraged | 36 | -19.02% | Nov 27, 2014 | RYOIX vs RMQAX | |
| Rydex NASDAQ-100 2x Strategy Fund | Leveraged Equities, Leveraged | 31 | -18.97% | May 23, 2000 | RYOIX vs RYVYX | |
| Rydex Electronics Fund | Technology Equities | 91 | 1.62% | Mar 31, 1998 | RYOIX vs RYSIX | |
| Rydex S&P 500 2x Strategy Fund | Leveraged Equities, Leveraged | 25 | -15.39% | May 18, 2000 | RYOIX vs RYTNX | |
| Rydex Dow Jones Industrial Average Fund | Large Cap Value Equities | 21 | -5.94% | Dec 1, 2015 | RYOIX vs RYDAX | |
| Rydex Nova Fund | Leveraged Equities, Leveraged | 30 | -11.41% | Jul 11, 1993 | RYOIX vs RYNVX | |
| Rydex Precious Metals Fund | Precious Metals | 90 | 1.40% | Nov 30, 1993 | RYOIX vs RYPMX | |
| Rydex Russell 2000 Fund | Small Cap Blend Equities | 40 | -3.06% | May 31, 2006 | RYOIX vs RYRRX | |
| Rydex Inverse NASDAQ-100 Strategy Fund | Inverse Equities, Leveraged | 2 | 10.70% | Sep 2, 1998 | RYOIX vs RYAIX | |
| Rydex S&P MidCap 400 Pure Growth Fund | Mid Cap Growth Equities | 44 | 0.34% | Feb 20, 2004 | RYOIX vs RYCKX |
Often Compared With RYOIX
What investors most often compare with RYOIX, based on PortfoliosLab usage data.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | Inception | |
|---|---|---|---|---|---|---|
| Vanguard S&P 500 ETF | S&P 500 | 65 | -4.42% | Sep 7, 2010 | RYOIX vs VOO |
Compare RYOIX with Any Fund or Stock
Compare RYOIX with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.