Rydex Biotechnology Fund (RYOIX) belongs to the Health & Biotech Equities category. Below you'll find alternative mutual funds from the same category, ranked by key criteria, plus funds that investors commonly compare with RYOIX. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to RYOIX
RYOIX charges 1.36% annually. There are 40 mutual funds in the Health & Biotech Equities category with lower expense ratios, going as low as 0.10%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Vanguard Health Care Index Fund Admiral Shares | 0.10% | 19.00B | Feb 2004 | RYOIX vs VHCIX | |
| Vanguard Health Care Fund Admiral Shares | 0.27% | 37.00B | Nov 2001 | RYOIX vs VGHAX | |
| Vanguard Health Care Fund Investor Shares | 0.33% | 37.00B | May 1984 | RYOIX vs VGHCX | |
| Fidelity Advisor Health Care Fund Class Z | 0.59% | — | Oct 2018 | RYOIX vs FIKCX | |
| Fidelity Advisor Biotechnology Fund Class Z | 0.61% | — | Oct 2018 | RYOIX vs FIJYX |
Best Risk-Adjusted Alternatives to RYOIX
RYOIX has a PortfoliosLab risk / return rank of 91. There are 10 mutual funds in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Franklin Biotechnology Discovery Fund | 96 | — | Sep 1997 | RYOIX vs FBDIX | |
| Fidelity Advisor Biotechnology Fund Class Z | 94 | — | Oct 2018 | RYOIX vs FIJYX | |
| Fidelity Advisor Biotechnology Fund I Class | 94 | — | Dec 2000 | RYOIX vs FBTIX | |
| Fidelity Advisor Biotechnology Fund Class A | 94 | — | Dec 2000 | RYOIX vs FBTAX | |
| Fidelity Advisor Biotechnology Fund Class M | 94 | — | Dec 2000 | RYOIX vs FBTTX |
Top Performing RYOIX Alternatives (YTD)
RYOIX is at 19.63% YTD. There are 7 mutual funds in the Health & Biotech Equities category with higher YTD returns, going as high as 24.40%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity Advisor Biotechnology Fund Class Z | 24.40% | — | Oct 2018 | RYOIX vs FIJYX | |
| Fidelity Advisor Biotechnology Fund I Class | 24.32% | — | Dec 2000 | RYOIX vs FBTIX | |
| Fidelity Advisor Biotechnology Fund Class A | 24.15% | — | Dec 2000 | RYOIX vs FBTAX | |
| Fidelity Advisor Biotechnology Fund Class M | 23.98% | — | Dec 2000 | RYOIX vs FBTTX | |
| Fidelity Advisor Biotechnology Fund Class C | 23.69% | — | Dec 2000 | RYOIX vs FBTCX |
Lowest Volatility Alternatives to RYOIX
RYOIX has 20.10% 1-year volatility. There are 34 mutual funds in the Health & Biotech Equities category with lower 1-year volatility, going as low as 14.13%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Invesco Health Care Fund | 14.13% | — | Aug 1989 | RYOIX vs GGHCX | |
| BlackRock Health Sciences Opportunities Portfolio | 14.93% | — | Dec 1999 | RYOIX vs SHSAX | |
| Health Sciences Opportunities Fund Class Instituti... | 14.94% | — | Oct 2000 | RYOIX vs SHSSX | |
| Live Oak Health Sciences Fund | 14.98% | — | Jun 2001 | RYOIX vs LOGSX | |
| Saratoga Health & Biotechnology Fund | 15.04% | — | Jul 1999 | RYOIX vs SHPAX |
Lowest Drawdown Alternatives to RYOIX
RYOIX has a 1-year max drawdown of -8.43%. There are 2 mutual funds in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as -7.62%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity Select Biotechnology Portfolio | -7.62% | — | Dec 1985 | RYOIX vs FBIOX | |
| Live Oak Health Sciences Fund | -8.13% | — | Jun 2001 | RYOIX vs LOGSX | |
| AlphaCentric LifeSci Healthcare Fund | -8.49% | — | Nov 2019 | RYOIX vs LYFIX | |
| Fidelity Advisor Biotechnology Fund Class Z | -8.88% | — | Oct 2018 | RYOIX vs FIJYX | |
| Fidelity Advisor Biotechnology Fund I Class | -8.90% | — | Dec 2000 | RYOIX vs FBTIX |
Other Mutual Funds from Rydex Funds
The 10 most viewed Rydex Funds mutual funds shown here include RYSIX, RMQAX, RYVYX and span 6 categories.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| Rydex Electronics Fund | Technology Equities | 93 | 77.01% | — | Mar 1998 | RYOIX vs RYSIX | |
| Rydex Monthly Rebalance NASDAQ-100 2x Strategy Fun... | Leveraged Equities | 46 | 31.90% | — | Nov 2014 | RYOIX vs RMQAX | |
| Rydex NASDAQ-100 2x Strategy Fund | Leveraged Equities | 45 | 32.74% | — | May 2000 | RYOIX vs RYVYX | |
| Rydex S&P 500 2x Strategy Fund | Leveraged Equities | 43 | 18.57% | — | May 2000 | RYOIX vs RYTNX | |
| Rydex Dow Jones Industrial Average Fund | Large Cap Value Equities | 41 | 9.55% | — | Dec 2015 | RYOIX vs RYDAX | |
| Rydex S&P 500 Pure Growth Fund | Large Cap Growth Equities | 45 | 29.02% | — | Feb 2004 | RYOIX vs RYGRX | |
| Rydex Precious Metals Fund | Precious Metals | 22 | -9.53% | — | Nov 1993 | RYOIX vs RYPMX | |
| Rydex Inverse S&P 500 Strategy Fund | Inverse Equities | 0 | -8.00% | — | Jan 1994 | RYOIX vs RYURX | |
| Rydex Inverse NASDAQ-100 Strategy Fund | Inverse Equities | 0 | -15.47% | — | Sep 1998 | RYOIX vs RYAIX | |
| Rydex Technology Fund | Technology Equities | 67 | 30.25% | — | Apr 1998 | RYOIX vs RYTIX |
Often Compared With RYOIX
Investors most often compare RYOIX with AHSAX, ETIHX, FHCCX. These 20 comparison targets span 5 categories, based on PortfoliosLab usage data.
Compare RYOIX with Any Fund or Stock
Compare RYOIX with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair RYOIX with funds that move differently
Rydex Biotechnology Fund alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to RYOIX.
Explore RYOIX Diversifiers