RYOIX vs. AHSAX

Last updated Aug 1, 2026

RYOIX (Rydex Biotechnology Fund) and AHSAX (Alger Health Sciences Fund) are both Health & Biotech Equities funds. Over the past 10 years, RYOIX returned 9.33%/yr vs 10.07%/yr for AHSAX. Their correlation of 0.87 means they have usually moved in the same direction. RYOIX charges 1.36%/yr vs 1.05%/yr for AHSAX.

Performance

RYOIX vs. AHSAX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Rydex Biotechnology Fund (RYOIX) and Alger Health Sciences Fund (AHSAX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, RYOIX achieves a 18.33% return, which is significantly lower than AHSAX's 23.38% return. Over the past 10 years, RYOIX has underperformed AHSAX with an annualized return of 9.33%, while AHSAX has yielded a comparatively higher 10.07% annualized return.

RYOIX

• 1D: 0.50%
• 1M: -3.93%
• 6M: 15.89%
• YTD: 18.33%
• 1Y: 50.09%
• 3Y*: 18.00%
• 5Y*: 6.19%
• 10Y*: 9.33%
• ALL TIME*: 10.91%

AHSAX

• 1D: 0.64%
• 1M: 7.49%
• 6M: 23.38%
• YTD: 23.38%
• 1Y: 55.59%
• 3Y*: 10.53%
• 5Y*: 0.59%
• 10Y*: 10.07%
• ALL TIME*: 7.65%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
AHSAX Alger Health Sciences Fund	$0.00	$0.00	$0.00
RYOIX Rydex Biotechnology Fund	$0.00	$0.00	$0.00

RYOIX vs. AHSAX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
RYOIX Rydex Biotechnology Fund	18.33%	30.62%	-0.95%	6.06%	-13.04%	2.05%	21.94%	30.69%	-8.94%	29.68%
AHSAX Alger Health Sciences Fund	23.38%	10.14%	1.17%	-4.26%	-17.04%	3.26%	30.99%	22.02%	5.71%	33.06%

Correlation

The correlation between RYOIX and AHSAX is 0.83, meaning they have usually moved in the same direction, including during past declines.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.83
Correlation (3Y) Balances recent behavior with more history.	0.76
Correlation (5Y) Shows whether the relationship held over a longer period.	0.82
Correlation (10Y) Provides a long-term view across more market conditions.	0.86
Correlation (All Time) Calculated using the full available price history since Jan 2, 2003	0.87

The correlation between RYOIX and AHSAX shifts across timeframes, from 0.76 (3 years) to 0.87 (all time), reflecting how their relationship changes across market environments.

Return for Risk

RYOIX vs. AHSAX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

RYOIX

RYOIX Risk / Return Rank: 93
RYOIX Sharpe Ratio Rank: 94
RYOIX Sortino Ratio Rank: 92
RYOIX Omega Ratio Rank: 85
RYOIX Calmar Ratio Rank: 98
RYOIX Martin Ratio Rank: 97

AHSAX

AHSAX Risk / Return Rank: 96
AHSAX Sharpe Ratio Rank: 98
AHSAX Sortino Ratio Rank: 97
AHSAX Omega Ratio Rank: 93
AHSAX Calmar Ratio Rank: 97
AHSAX Martin Ratio Rank: 96

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

RYOIX vs. AHSAX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Rydex Biotechnology Fund (RYOIX) and Alger Health Sciences Fund (AHSAX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	RYOIX	AHSAX	Difference
Sharpe ratio: Return per unit of total volatility	2.52	3.18	-0.67
Sortino ratio: Return per unit of downside risk	3.54	4.38	-0.84
Omega ratio: Gain probability vs. loss probability	1.41	1.53	-0.12
Calmar ratio: Return relative to maximum drawdown	5.92	5.55	+0.37
Martin ratio: Return relative to average drawdown	19.14	17.97	+1.17

RYOIX vs. AHSAX - Sharpe Ratio Comparison

The current RYOIX Sharpe Ratio is 2.52, which is comparable to the AHSAX Sharpe Ratio of 3.18. The chart below compares the historical Sharpe Ratios of RYOIX and AHSAX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

RYOIX vs. AHSAX - Drawdown Comparison

The maximum RYOIX drawdown since its inception was -74.43%, which is greater than AHSAX's maximum drawdown of -46.23%. Use the drawdown chart below to compare losses from any high point for RYOIX and AHSAX.

Drawdown Indicators

	RYOIX	AHSAX	Difference
Max Drawdown Largest peak-to-trough decline	-74.43%	-46.23%	-28.20%
Max Drawdown (1Y) Largest decline over 1 year	-8.43%	-9.67%	+1.24%
Max Drawdown (3Y) Largest decline over 3 years	-23.47%	-23.11%	-0.36%
Max Drawdown (5Y) Largest decline over 5 years	-33.66%	-45.04%	+11.38%
Max Drawdown (10Y) Largest decline over 10 years	-33.66%	-45.04%	+11.38%
Current Drawdown Current decline from peak	-4.80%	-10.27%	+5.47%
Average Drawdown Average peak-to-trough decline	-27.49%	-14.73%	-12.76%
Ulcer Index Depth and duration of drawdowns from previous peaks	2.60%	2.99%	-0.39%

Volatility

RYOIX vs. AHSAX - Volatility Comparison

The current volatility for Rydex Biotechnology Fund (RYOIX) is 5.73%, while Alger Health Sciences Fund (AHSAX) has a volatility of 6.39%. This indicates that RYOIX experiences smaller price fluctuations and is considered to be less risky than AHSAX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	RYOIX	AHSAX	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.73%	6.39%	-0.66%
Volatility (6M) Calculated over the trailing 6-month period	15.28%	13.29%	+1.99%
Volatility (1Y) Calculated over the trailing 1-year period	19.84%	16.89%	+2.95%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	21.32%	24.31%	-2.99%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	23.13%	23.37%	-0.24%

RYOIX vs. AHSAX - Expense Ratio Comparison

RYOIX has a 1.36% expense ratio, which is higher than AHSAX's 1.05% expense ratio.

Dividends

RYOIX vs. AHSAX - Dividend Comparison

RYOIX's dividend yield for the trailing twelve months is around 10.62%, while AHSAX has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
AHSAX Alger Health Sciences Fund	0.00%	0.00%	0.00%	0.00%	0.00%	27.18%	11.68%	6.98%	7.82%	0.00%	0.00%	0.00%
RYOIX Rydex Biotechnology Fund	10.62%	12.57%	14.61%	0.00%	1.29%	19.39%	7.28%	8.58%	14.11%	5.38%	0.00%	1.45%

Frequently Asked Questions

Can I hold both RYOIX and AHSAX in my portfolio?

RYOIX and AHSAX have a correlation of 0.83, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, RYOIX or AHSAX?

AHSAX has higher volatility (6.39%) compared to RYOIX (5.73%). In terms of maximum drawdown, RYOIX dropped -74.43% vs AHSAX's -46.23%.

Which has better risk-adjusted returns?

AHSAX currently has the higher Sharpe Ratio (3.18 vs 2.52), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.