ARK Genomic Revolution Multi-Sector ETF (ARKG) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with ARKG. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to ARKG
ARKG charges 0.75% annually. There are 48 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | ARKG vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 41.65B | Dec 1998 | ARKG vs XLV | |
| Vanguard Health Care ETF | 0.09% | 19.00B | Jan 2004 | ARKG vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 951.16M | Nov 2025 | ARKG vs PBPH | |
| GSK plc ADRhedged ETF | 0.19% | 793.18K | Jan 2025 | ARKG vs GSKH |
Best Risk-Adjusted Alternatives to ARKG
ARKG has a PortfoliosLab risk / return rank of 49. There are 38 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 57.56M | Dec 2014 | ARKG vs BBC | |
| ALPS Medical Breakthroughs ETF | 94 | 213.08M | Dec 2014 | ARKG vs SBIO | |
| First Trust Nasdaq Pharmaceuticals ETF | 94 | 36.36M | Sep 2016 | ARKG vs FTXH | |
| iShares U.S. Pharmaceuticals ETF | 93 | 1.34B | May 2006 | ARKG vs IHE | |
| SPDR S&P Biotech ETF | 93 | 11.10B | Feb 2006 | ARKG vs XBI |
Top Performing ARKG Alternatives (YTD)
ARKG is at 38.38% YTD. There is 1 ETF in the Health & Biotech Equities category with a higher YTD return, going as high as 41.35%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 41.35% | 44.37M | Sep 2021 | ARKG vs PSIL | |
| Roundhill UNH WeeklyPay ETF | 31.46% | 6.01M | Dec 2025 | ARKG vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 29.44% | 57.56M | Dec 2014 | ARKG vs BBC | |
| SPDR S&P Health Care Services ETF | 26.76% | 204.10M | Sep 2011 | ARKG vs XHS | |
| iShares Genomics Immunology and Healthcare ETF Gen... | 25.19% | 195.75M | Jun 2019 | ARKG vs IDNA |
Lowest Volatility Alternatives to ARKG
ARKG has 42.93% 1-year volatility. There are 64 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | ARKG vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | ARKG vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.62% | 10.11M | Jun 2007 | ARKG vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 11.06% | 16.78M | Jul 2025 | ARKG vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 11.54% | 982.35K | Apr 2026 | ARKG vs MHIP |
Lowest Drawdown Alternatives to ARKG
ARKG has a 1-year max drawdown of -27.51%. There are 54 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | ARKG vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.32% | 10.11M | Jun 2007 | ARKG vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 36.36M | Sep 2016 | ARKG vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 74.65M | Jun 2021 | ARKG vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 1.34B | May 2006 | ARKG vs IHE |
Other ETFs from ARK
The 9 most viewed ARK ETFs shown here include ARKK, ARKQ, ARKW and span 7 categories. AUM among these funds goes as high as $7B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| ARK Innovation ETF | Technology Equities | 10 | -0.33% | 7.26B | Oct 2014 | ARKG vs ARKK | |
| ARK Autonomous Technology & Robotics ETF | Robotics, Technology Equities, Actively Managed | 24 | 3.04% | 2.22B | Sep 2014 | ARKG vs ARKQ | |
| ARK Next Generation Internet ETF | Mid Cap Growth Equities, Technology Equities | 8 | -2.33% | 1.83B | Sep 2014 | ARKG vs ARKW | |
| ARK Space Exploration & Innovation ETF | Aerospace & Defense | 20 | 6.18% | 1.11B | Mar 2021 | ARKG vs ARKX | |
| ARK 21Shares Bitcoin ETF | Cryptocurrency | 2 | -26.62% | 2.44B | Jan 2024 | ARKG vs ARKB | |
| ARK Fintech Innovation ETF | Blockchain | 4 | -13.21% | 834.90M | Feb 2019 | ARKG vs ARKF | |
| ARK Israel Innovative Technology ETF | Technology Equities | 21 | 1.29% | 151.90M | Dec 2017 | ARKG vs IZRL | |
| ARK The 3D Printing ETF | Technology Equities | 18 | 7.43% | 67.70M | Jul 2016 | ARKG vs PRNT | |
| ARK 21Shares Digital Asset and Blockchain Strategy... | Cryptocurrency | — | — | 1.50M | Nov 2023 | ARKG vs ARKD |
Often Compared With ARKG
Investors most often compare ARKG with IBB, GNOM, SPY. These 20 comparison targets span 6 categories, based on PortfoliosLab usage data.
Compare ARKG with Any Fund or Stock
Compare ARKG with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair ARKG with funds that move differently
ARK Genomic Revolution Multi-Sector ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to ARKG.
Explore ARKG Diversifiers