ZYME vs. SPY
ZYME (Zymeworks Inc.) is a stock, while SPY (State Street SPDR S&P 500 ETF) is S&P 500 fund tracking the S&P 500 Index. Over the past 5 years, ZYME returned -8.24%/yr vs 13.05%/yr for SPY. At a 0.27 correlation, their price movements are largely independent.
Performance
ZYME vs. SPY - Performance Comparison
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Returns By Period
In the year-to-date period, ZYME achieves a -9.30% return, which is significantly lower than SPY's 8.15% return.
ZYME
- 1D
- 2.67%
- 1M
- -6.76%
- YTD
- -9.30%
- 6M
- -10.86%
- 1Y
- 91.50%
- 3Y*
- 43.33%
- 5Y*
- -8.24%
- 10Y*
- —
SPY
- 1D
- -1.45%
- 1M
- -1.36%
- YTD
- 8.15%
- 6M
- 7.20%
- 1Y
- 23.59%
- 3Y*
- 20.68%
- 5Y*
- 13.05%
- 10Y*
- 15.53%
ZYME vs. SPY - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
ZYME Zymeworks Inc. | -9.30% | 79.85% | 40.90% | 32.19% | -52.04% | -65.32% | 3.96% | 209.67% | 93.33% | -43.75% |
SPY State Street SPDR S&P 500 ETF | 8.15% | 17.72% | 24.89% | 26.18% | -18.18% | 28.73% | 18.33% | 31.22% | -4.57% | 13.52% |
Correlation
The correlation between ZYME and SPY is 0.31, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.31 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.31 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.27 |
Correlation (All Time) Calculated using the full available price history since Apr 28, 2017 | 0.27 |
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Return for Risk
ZYME vs. SPY — Risk / Return Rank
ZYME
SPY
ZYME vs. SPY - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Zymeworks Inc. (ZYME) and State Street SPDR S&P 500 ETF (SPY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| ZYME | SPY | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.16 | ||
| Sortino ratioReturn per unit of downside risk | +0.11 | ||
| Omega ratioGain probability vs. loss probability | 1.33 | 1.34 | -0.02 |
| Calmar ratioReturn relative to maximum drawdown | 4.33 | 2.67 | +1.66 |
| Martin ratioReturn relative to average drawdown | 9.21 | 11.92 | -2.71 |
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Drawdowns
ZYME vs. SPY - Drawdown Comparison
The maximum ZYME drawdown since its inception was -91.81%, which is greater than SPY's maximum drawdown of -55.19%. Use the drawdown chart below to compare losses from any high point for ZYME and SPY.
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Drawdown Indicators
| ZYME | SPY | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -91.81% | -55.19% | -36.62% |
Max Drawdown (1Y)Largest decline over 1 year | -21.25% | -8.88% | -12.37% |
Max Drawdown (3Y)Largest decline over 3 years | -45.75% | -18.76% | -26.99% |
Max Drawdown (5Y)Largest decline over 5 years | -87.53% | -24.50% | -63.03% |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.72% | — |
Current DrawdownCurrent decline from peak | -57.97% | -3.17% | -54.80% |
Average DrawdownAverage peak-to-trough decline | -52.54% | -9.04% | -43.50% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 9.97% | 1.98% | +7.99% |
Volatility
ZYME vs. SPY - Volatility Comparison
Zymeworks Inc. (ZYME) has a higher volatility of 10.12% compared to State Street SPDR S&P 500 ETF (SPY) at 4.87%. This indicates that ZYME's price experiences larger fluctuations and is considered to be riskier than SPY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ZYME | SPY | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 10.12% | 4.87% | +5.25% |
Volatility (6M)Calculated over the trailing 6-month period | 29.45% | 9.85% | +19.60% |
Volatility (1Y)Calculated over the trailing 1-year period | 52.91% | 12.50% | +40.41% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 61.85% | 17.15% | +44.70% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 61.45% | 17.95% | +43.50% |
Dividends
ZYME vs. SPY - Dividend Comparison
ZYME has not paid dividends to shareholders, while SPY's dividend yield for the trailing twelve months is around 1.03%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
SPY State Street SPDR S&P 500 ETF | 1.03% | 1.07% | 1.21% | 1.40% | 1.65% | 1.20% | 1.52% | 1.75% | 2.04% | 1.80% | 2.03% | 2.06% |
ZYME Zymeworks Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
ZYME and SPY have a correlation of 0.31, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ZYME has higher volatility (10.12%) compared to SPY (4.87%). In terms of maximum drawdown, ZYME dropped -91.81% vs SPY's -55.19%.
SPY currently has the higher Sharpe Ratio (1.90 vs 1.74), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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