ZYME vs. UMBF

Last updated Apr 2, 2026

Compare and contrast key facts about Zymeworks Inc. (ZYME) and UMB Financial Corporation (UMBF).

Performance

ZYME vs. UMBF - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Zymeworks Inc. (ZYME) and UMB Financial Corporation (UMBF). The values are adjusted to include any dividend payments, if applicable.

ZYME vs. UMBF - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ZYME Zymeworks Inc.	-1.48%	79.85%	40.90%	32.19%	-52.04%	-65.32%	3.96%	209.67%	93.33%	-41.59%
UMBF UMB Financial Corporation	0.04%	3.44%	37.34%	2.21%	-19.97%	56.04%	2.64%	14.71%	-13.86%	0.34%

Fundamentals

EPS ZYME : -$1.07 UMBF : $13.90
Total Revenue (TTM) ZYME : -$27.11M UMBF : $4.25B
Gross Profit (TTM) ZYME : -$27.11M UMBF : $1.70B
EBITDA (TTM) ZYME : -$79.57M UMBF : $739.37M

Returns By Period

In the year-to-date period, ZYME achieves a -1.48% return, which is significantly lower than UMBF's 0.04% return.

ZYME

• 1D: 3.59%
• 1M: 11.28%
• YTD: -1.48%
• 6M: 53.13%
• 1Y: 123.24%
• 3Y*: 42.10%
• 5Y*: -3.79%
• 10Y*: —

UMBF

• 1D: 1.65%
• 1M: -2.18%
• YTD: 0.04%
• 6M: -2.35%
• 1Y: 15.73%
• 3Y*: 27.91%
• 5Y*: 6.15%
• 10Y*: 10.10%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ZYME vs. UMBF — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ZYME

ZYME Risk / Return Rank: 92
ZYME Sharpe Ratio Rank: 92
ZYME Sortino Ratio Rank: 92
ZYME Omega Ratio Rank: 88
ZYME Calmar Ratio Rank: 94
ZYME Martin Ratio Rank: 92

UMBF

UMBF Risk / Return Rank: 56
UMBF Sharpe Ratio Rank: 58
UMBF Sortino Ratio Rank: 51
UMBF Omega Ratio Rank: 52
UMBF Calmar Ratio Rank: 59
UMBF Martin Ratio Rank: 59

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ZYME vs. UMBF - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Zymeworks Inc. (ZYME) and UMB Financial Corporation (UMBF). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ZYME	UMBF	Difference
Sharpe ratio Return per unit of total volatility	2.22	0.49	+1.73
Sortino ratio Return per unit of downside risk	3.14	0.86	+2.29
Omega ratio Gain probability vs. loss probability	1.38	1.12	+0.26
Calmar ratio Return relative to maximum drawdown	5.66	0.81	+4.85
Martin ratio Return relative to average drawdown	12.89	1.84	+11.04
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ZYME vs. UMBF - Sharpe Ratio Comparison

The current ZYME Sharpe Ratio is 2.22, which is higher than the UMBF Sharpe Ratio of 0.49. The chart below compares the historical Sharpe Ratios of ZYME and UMBF, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ZYME	UMBF	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.22	0.49	+1.73
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.06	0.19	-0.25
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.30	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.13	0.25	-0.12

Correlation

The correlation between ZYME and UMBF is 0.17, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ZYME vs. UMBF - Dividend Comparison

ZYME has not paid dividends to shareholders, while UMBF's dividend yield for the trailing twelve months is around 1.45%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ZYME Zymeworks Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
UMBF UMB Financial Corporation	1.45%	1.42%	1.39%	1.83%	1.78%	1.30%	1.81%	1.76%	1.92%	1.45%	1.28%	2.04%

Drawdowns

ZYME vs. UMBF - Drawdown Comparison

The maximum ZYME drawdown since its inception was -91.81%, which is greater than UMBF's maximum drawdown of -52.70%. Use the drawdown chart below to compare losses from any high point for ZYME and UMBF.

Drawdown Indicators

	ZYME	UMBF	Difference
Max Drawdown Largest peak-to-trough decline	-91.81%	-52.70%	-39.11%
Max Drawdown (1Y) Largest decline over 1 year	-20.81%	-18.57%	-2.24%
Max Drawdown (5Y) Largest decline over 5 years	-87.84%	-50.25%	-37.59%
Max Drawdown (10Y) Largest decline over 10 years	—	-50.25%	—
Current Drawdown Current decline from peak	-54.34%	-14.32%	-40.02%
Average Drawdown Average peak-to-trough decline	-52.39%	-17.83%	-34.56%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.14%	8.17%	+0.97%

Volatility

ZYME vs. UMBF - Volatility Comparison

Zymeworks Inc. (ZYME) has a higher volatility of 14.12% compared to UMB Financial Corporation (UMBF) at 6.69%. This indicates that ZYME's price experiences larger fluctuations and is considered to be riskier than UMBF based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ZYME	UMBF	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.12%	6.69%	+7.43%
Volatility (6M) Calculated over the trailing 6-month period	41.40%	21.08%	+20.32%
Volatility (1Y) Calculated over the trailing 1-year period	55.93%	32.18%	+23.75%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	62.51%	33.38%	+29.13%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	61.89%	33.53%	+28.36%

Financials