ZYME vs. CALM

Last updated Aug 1, 2026

ZYME (Zymeworks Inc.) and CALM (Cal-Maine Foods, Inc.) are both stocks. ZYME operates in Biotechnology (Healthcare), while CALM operates in Farm Products (Consumer Defensive). Over the past 5 years, ZYME returned -7.32%/yr vs 26.60%/yr for CALM. Their 0.07 correlation means their historical movements had little consistent relationship.

Performance

ZYME vs. CALM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Zymeworks Inc. (ZYME) and Cal-Maine Foods, Inc. (CALM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ZYME achieves a -16.67% return, which is significantly lower than CALM's 11.79% return.

ZYME

• 1D: -3.39%
• 1M: -16.61%
• 6M: -2.62%
• YTD: -16.67%
• 1Y: 74.54%
• 3Y*: 43.34%
• 5Y*: -7.32%
• 10Y*: —
• ALL TIME*: 5.39%

CALM

• 1D: 0.80%
• 1M: 4.69%
• 6M: 5.58%
• YTD: 11.79%
• 1Y: -14.37%
• 3Y*: 31.12%
• 5Y*: 26.60%
• 10Y*: 10.82%
• ALL TIME*: 16.54%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
CALM Cal-Maine Foods, Inc.	$107.67M	$90.60M	$71.32M
ZYME Zymeworks Inc.	$8.52M	$11.24M	$15.30M

ZYME vs. CALM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ZYME Zymeworks Inc.	-16.67%	79.85%	40.90%	32.19%	-52.04%	-65.32%	3.96%	209.67%	93.33%	-43.75%
CALM Cal-Maine Foods, Inc.	11.79%	-15.61%	87.00%	14.48%	51.87%	-1.38%	-12.19%	2.09%	-3.90%	14.56%

Correlation

The correlation between ZYME and CALM is -0.02, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	-0.02
Correlation (3Y) Balances recent behavior with more history.	0.07
Correlation (5Y) Shows whether the relationship held over a longer period.	0.05
Correlation (All Time) Calculated using the full available price history since Apr 28, 2017	0.07

Fundamentals

Market Cap ZYME : $1.61B CALM : $4.12B
EPS ZYME : -$587.50 CALM : $6.63
PS Ratio ZYME : 20.94 CALM : 1.44
PB Ratio ZYME : 0.01 CALM : 1.57
Total Revenue (TTM) ZYME : $78.86M CALM : $2.91B
Gross Profit (TTM) ZYME : $77.16M CALM : $672.05M
EBITDA (TTM) ZYME : -$47.18B CALM : $515.05M

Return for Risk

ZYME vs. CALM — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ZYME

ZYME Risk / Return Rank: 85
ZYME Sharpe Ratio Rank: 84
ZYME Sortino Ratio Rank: 85
ZYME Omega Ratio Rank: 82
ZYME Calmar Ratio Rank: 88
ZYME Martin Ratio Rank: 85

CALM

CALM Risk / Return Rank: 23
CALM Sharpe Ratio Rank: 18
CALM Sortino Ratio Rank: 19
CALM Omega Ratio Rank: 20
CALM Calmar Ratio Rank: 28
CALM Martin Ratio Rank: 32

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ZYME vs. CALM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Zymeworks Inc. (ZYME) and Cal-Maine Foods, Inc. (CALM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ZYME	CALM	Difference
Sharpe ratio: Return per unit of total volatility	1.41	-0.56	+1.98
Sortino ratio: Return per unit of downside risk	2.36	-0.64	+3.00
Omega ratio: Gain probability vs. loss probability	1.28	0.93	+0.36
Calmar ratio: Return relative to maximum drawdown	3.24	-0.46	+3.70
Martin ratio: Return relative to average drawdown	6.93	-0.66	+7.59

ZYME vs. CALM - Sharpe Ratio Comparison

The current ZYME Sharpe Ratio is 1.41, which is higher than the CALM Sharpe Ratio of -0.56. The chart below compares the historical Sharpe Ratios of ZYME and CALM, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ZYME vs. CALM - Drawdown Comparison

The maximum ZYME drawdown since its inception was -91.81%, which is greater than CALM's maximum drawdown of -74.08%. Use the drawdown chart below to compare losses from any high point for ZYME and CALM.

Drawdown Indicators

	ZYME	CALM	Difference
Max Drawdown Largest peak-to-trough decline	-91.81%	-74.08%	-17.73%
Max Drawdown (1Y) Largest decline over 1 year	-23.18%	-37.00%	+13.82%
Max Drawdown (3Y) Largest decline over 3 years	-45.75%	-37.00%	-8.75%
Max Drawdown (5Y) Largest decline over 5 years	-87.12%	-37.00%	-50.12%
Max Drawdown (10Y) Largest decline over 10 years	—	-39.12%	—
Current Drawdown Current decline from peak	-61.38%	-22.64%	-38.74%
Average Drawdown Average peak-to-trough decline	-52.60%	-30.29%	-22.31%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.81%	25.62%	-14.81%

Volatility

ZYME vs. CALM - Volatility Comparison

The current volatility for Zymeworks Inc. (ZYME) is 11.47%, while Cal-Maine Foods, Inc. (CALM) has a volatility of 13.24%. This indicates that ZYME experiences smaller price fluctuations and is considered to be less risky than CALM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ZYME	CALM	Difference
Volatility (1M) Calculated over the trailing 1-month period	11.47%	13.24%	-1.77%
Volatility (6M) Calculated over the trailing 6-month period	29.83%	22.88%	+6.95%
Volatility (1Y) Calculated over the trailing 1-year period	53.17%	30.03%	+23.14%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	61.90%	33.05%	+28.85%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	61.29%	31.34%	+29.95%

Dividends

ZYME vs. CALM - Dividend Comparison

ZYME has not paid dividends to shareholders, while CALM's dividend yield for the trailing twelve months is around 5.47%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CALM Cal-Maine Foods, Inc.	5.47%	10.90%	2.82%	7.51%	3.17%	0.09%	0.00%	0.98%	1.03%	0.00%	2.70%	4.10%
ZYME Zymeworks Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both ZYME and CALM in my portfolio?

ZYME and CALM have a correlation of -0.02, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ZYME or CALM?

CALM has higher volatility (13.24%) compared to ZYME (11.47%). In terms of maximum drawdown, ZYME dropped -91.81% vs CALM's -74.08%.

Which has better risk-adjusted returns?

ZYME currently has the higher Sharpe Ratio (1.41 vs -0.56), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.