ZYME vs. ASAN

Last updated Apr 1, 2026

Compare and contrast key facts about Zymeworks Inc. (ZYME) and Asana, Inc. (ASAN).

Performance

ZYME vs. ASAN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Zymeworks Inc. (ZYME) and Asana, Inc. (ASAN). The values are adjusted to include any dividend payments, if applicable.

ZYME vs. ASAN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
ZYME Zymeworks Inc.	-4.90%	79.85%	40.90%	32.19%	-52.04%	-65.32%	1.46%
ASAN Asana, Inc.	-53.32%	-32.36%	6.63%	38.05%	-81.53%	152.28%	2.60%

Fundamentals

Market Cap ZYME : $1.89B ASAN : $1.53B
EPS ZYME : -$1.07 ASAN : -$0.80
PB Ratio ZYME : 7.03 ASAN : 9.90
Total Revenue (TTM) ZYME : -$27.11M ASAN : $790.81M
Gross Profit (TTM) ZYME : -$27.11M ASAN : $704.05M
EBITDA (TTM) ZYME : -$79.57M ASAN : -$168.67M

Returns By Period

In the year-to-date period, ZYME achieves a -4.90% return, which is significantly higher than ASAN's -53.32% return.

ZYME

• 1D: 3.43%
• 1M: 7.51%
• YTD: -4.90%
• 6M: 46.60%
• 1Y: 110.24%
• 3Y*: 40.44%
• 5Y*: -4.46%
• 10Y*: —

ASAN

• 1D: 3.06%
• 1M: -9.86%
• YTD: -53.32%
• 6M: -52.10%
• 1Y: -56.07%
• 3Y*: -32.84%
• 5Y*: -26.97%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ZYME vs. ASAN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ZYME

ZYME Risk / Return Rank: 90
ZYME Sharpe Ratio Rank: 90
ZYME Sortino Ratio Rank: 91
ZYME Omega Ratio Rank: 87
ZYME Calmar Ratio Rank: 93
ZYME Martin Ratio Rank: 90

ASAN

ASAN Risk / Return Rank: 7
ASAN Sharpe Ratio Rank: 5
ASAN Sortino Ratio Rank: 6
ASAN Omega Ratio Rank: 6
ASAN Calmar Ratio Rank: 11
ASAN Martin Ratio Rank: 6

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ZYME vs. ASAN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Zymeworks Inc. (ZYME) and Asana, Inc. (ASAN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ZYME	ASAN	Difference
Sharpe ratio Return per unit of total volatility	1.99	-1.00	+2.99
Sortino ratio Return per unit of downside risk	2.93	-1.52	+4.45
Omega ratio Gain probability vs. loss probability	1.35	0.81	+0.54
Calmar ratio Return relative to maximum drawdown	4.92	-0.84	+5.76
Martin ratio Return relative to average drawdown	11.21	-1.67	+12.89
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ZYME vs. ASAN - Sharpe Ratio Comparison

The current ZYME Sharpe Ratio is 1.99, which is higher than the ASAN Sharpe Ratio of -1.00. The chart below compares the historical Sharpe Ratios of ZYME and ASAN, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ZYME	ASAN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.99	-1.00	+2.99
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.07	-0.35	+0.28
Sharpe Ratio (All Time) Calculated using the full available price history	0.12	-0.31	+0.44

Correlation

The correlation between ZYME and ASAN is 0.25, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ZYME vs. ASAN - Dividend Comparison

Neither ZYME nor ASAN has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

ZYME vs. ASAN - Drawdown Comparison

The maximum ZYME drawdown since its inception was -91.81%, roughly equal to the maximum ASAN drawdown of -95.76%. Use the drawdown chart below to compare losses from any high point for ZYME and ASAN.

Drawdown Indicators

	ZYME	ASAN	Difference
Max Drawdown Largest peak-to-trough decline	-91.81%	-95.76%	+3.95%
Max Drawdown (1Y) Largest decline over 1 year	-20.81%	-68.16%	+47.35%
Max Drawdown (5Y) Largest decline over 5 years	-87.84%	-95.76%	+7.92%
Current Drawdown Current decline from peak	-55.92%	-95.51%	+39.59%
Average Drawdown Average peak-to-trough decline	-52.39%	-69.77%	+17.38%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.13%	34.06%	-24.93%

Volatility

ZYME vs. ASAN - Volatility Comparison

Zymeworks Inc. (ZYME) has a higher volatility of 14.47% compared to Asana, Inc. (ASAN) at 13.48%. This indicates that ZYME's price experiences larger fluctuations and is considered to be riskier than ASAN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ZYME	ASAN	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.47%	13.48%	+0.99%
Volatility (6M) Calculated over the trailing 6-month period	41.29%	37.90%	+3.39%
Volatility (1Y) Calculated over the trailing 1-year period	55.99%	56.04%	-0.05%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	62.49%	78.01%	-15.52%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	61.90%	76.64%	-14.74%

Financials