XDNA.TO vs. FHH.TO
XDNA.TO (iShares Genomics Immunology and Healthcare Index ETF) and FHH.TO (First Trust AlphaDEX U.S. Health Care Sector Index ETF) are both Health & Biotech Equities funds - XDNA.TO tracks the NYSE FactSet Global Genomics and Immuno Biopharma Index while FHH.TO tracks the StrataQuant Health Care Index. Both are passively managed. Over the past 3 years, XDNA.TO returned 14.14%/yr vs 6.39%/yr for FHH.TO. At a 0.42 correlation, their price movements are largely independent.
Performance
XDNA.TO vs. FHH.TO - Performance Comparison
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Returns By Period
In the year-to-date period, XDNA.TO achieves a 28.27% return, which is significantly higher than FHH.TO's 9.08% return.
XDNA.TO
- 1D
- -0.71%
- 1M
- 10.45%
- 6M
- 16.34%
- YTD
- 28.27%
- 1Y
- 59.77%
- 3Y*
- 14.14%
- 5Y*
- —
- 10Y*
- —
FHH.TO
- 1D
- -2.10%
- 1M
- 4.64%
- 6M
- 6.33%
- YTD
- 9.08%
- 1Y
- 25.19%
- 3Y*
- 6.39%
- 5Y*
- 4.14%
- 10Y*
- 8.42%
XDNA.TO vs. FHH.TO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 28.27% | 12.10% | 5.54% | -7.84% | -14.85% |
FHH.TO First Trust AlphaDEX U.S. Health Care Sector Index ETF | 9.08% | 5.83% | 9.13% | -6.00% | 6.15% |
Correlation
The correlation between XDNA.TO and FHH.TO is 0.42, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.42 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.42 |
Correlation (All Time) Calculated using the full available price history since May 4, 2022 | 0.42 |
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Return for Risk
XDNA.TO vs. FHH.TO — Risk / Return Rank
XDNA.TO
FHH.TO
XDNA.TO vs. FHH.TO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO) and First Trust AlphaDEX U.S. Health Care Sector Index ETF (FHH.TO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| XDNA.TO | FHH.TO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.94 | ||
| Sortino ratioReturn per unit of downside risk | +1.09 | ||
| Omega ratioGain probability vs. loss probability | 1.39 | 1.25 | +0.14 |
| Calmar ratioReturn relative to maximum drawdown | 6.95 | 1.80 | +5.15 |
| Martin ratioReturn relative to average drawdown | 15.82 | 4.88 | +10.94 |
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Drawdowns
XDNA.TO vs. FHH.TO - Drawdown Comparison
The maximum XDNA.TO drawdown since its inception was -45.90%, which is greater than FHH.TO's maximum drawdown of -25.83%. Use the drawdown chart below to compare losses from any high point for XDNA.TO and FHH.TO.
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Drawdown Indicators
| XDNA.TO | FHH.TO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -45.90% | -25.83% | -20.07% |
Max Drawdown (1Y)Largest decline over 1 year | -8.64% | -12.91% | +4.27% |
Max Drawdown (3Y)Largest decline over 3 years | -28.29% | -20.20% | -8.09% |
Max Drawdown (5Y)Largest decline over 5 years | — | -21.86% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -23.58% | — |
Current DrawdownCurrent decline from peak | -7.51% | -4.65% | -2.86% |
Average DrawdownAverage peak-to-trough decline | -22.98% | -8.37% | -14.61% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.79% | 4.76% | -0.97% |
Volatility
XDNA.TO vs. FHH.TO - Volatility Comparison
iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO) has a higher volatility of 7.90% compared to First Trust AlphaDEX U.S. Health Care Sector Index ETF (FHH.TO) at 5.58%. This indicates that XDNA.TO's price experiences larger fluctuations and is considered to be riskier than FHH.TO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| XDNA.TO | FHH.TO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.90% | 5.58% | +2.32% |
Volatility (6M)Calculated over the trailing 6-month period | 18.84% | 11.85% | +6.99% |
Volatility (1Y)Calculated over the trailing 1-year period | 25.66% | 16.59% | +9.07% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 25.41% | 15.99% | +9.42% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 25.41% | 16.71% | +8.70% |
Dividends
XDNA.TO vs. FHH.TO - Dividend Comparison
XDNA.TO's dividend yield for the trailing twelve months is around 0.25%, less than FHH.TO's 0.59% yield.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
FHH.TO First Trust AlphaDEX U.S. Health Care Sector Index ETF | 0.59% | 0.12% | 0.22% | 0.23% | 0.39% | 5.28% |
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 0.25% | 0.43% | 0.32% | 0.25% | 0.32% | 0.00% |
Frequently Asked Questions
XDNA.TO and FHH.TO have a correlation of 0.42, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
XDNA.TO tracks NYSE FactSet Global Genomics and Immuno Biopharma Index, while FHH.TO tracks StrataQuant Health Care Index. They also come from different issuers: iShares and First Trust.
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