XBIO vs. XBIT

Last updated Apr 2, 2026

Compare and contrast key facts about Xenetic Biosciences, Inc. (XBIO) and XBiotech Inc. (XBIT).

Performance

XBIO vs. XBIT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Xenetic Biosciences, Inc. (XBIO) and XBiotech Inc. (XBIT). The values are adjusted to include any dividend payments, if applicable.

XBIO vs. XBIT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
XBIO Xenetic Biosciences, Inc.	29.95%	-45.61%	15.65%	21.01%	-77.90%	-36.76%	41.67%	-92.68%	-14.54%	-55.37%
XBIT XBiotech Inc.	-2.09%	-39.49%	-1.25%	13.96%	-68.46%	-17.46%	-16.15%	267.42%	28.93%	-61.07%

Fundamentals

EPS XBIO : -$2.05 XBIT : -$0.96
Total Revenue (TTM) XBIO : $2.86M XBIT : $0.00
Gross Profit (TTM) XBIO : $2.86M XBIT : -$427.00K
EBITDA (TTM) XBIO : -$3.29M XBIT : -$27.00M

Returns By Period

In the year-to-date period, XBIO achieves a 29.95% return, which is significantly higher than XBIT's -2.09% return. Over the past 10 years, XBIO has underperformed XBIT with an annualized return of -45.52%, while XBIT has yielded a comparatively higher -11.73% annualized return.

XBIO

• 1D: 5.22%
• 1M: 10.59%
• YTD: 29.95%
• 6M: -9.03%
• 1Y: 14.63%
• 3Y*: -11.44%
• 5Y*: -33.07%
• 10Y*: -45.52%

XBIT

• 1D: -0.43%
• 1M: 0.86%
• YTD: -2.09%
• 6M: -11.36%
• 1Y: -22.52%
• 3Y*: -12.14%
• 5Y*: -30.80%
• 10Y*: -11.73%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

XBIO vs. XBIT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

XBIO

XBIO Risk / Return Rank: 54
XBIO Sharpe Ratio Rank: 43
XBIO Sortino Ratio Rank: 72
XBIO Omega Ratio Rank: 69
XBIO Calmar Ratio Rank: 43
XBIO Martin Ratio Rank: 42

XBIT

XBIT Risk / Return Rank: 21
XBIT Sharpe Ratio Rank: 23
XBIT Sortino Ratio Rank: 24
XBIT Omega Ratio Rank: 24
XBIT Calmar Ratio Rank: 16
XBIT Martin Ratio Rank: 19

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

XBIO vs. XBIT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Xenetic Biosciences, Inc. (XBIO) and XBiotech Inc. (XBIT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	XBIO	XBIT	Difference
Sharpe ratio Return per unit of total volatility	0.09	-0.38	+0.47
Sortino ratio Return per unit of downside risk	1.78	-0.22	+1.99
Omega ratio Gain probability vs. loss probability	1.22	0.98	+0.24
Calmar ratio Return relative to maximum drawdown	0.10	-0.70	+0.80
Martin ratio Return relative to average drawdown	0.15	-1.17	+1.32
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

XBIO vs. XBIT - Sharpe Ratio Comparison

The current XBIO Sharpe Ratio is 0.09, which is higher than the XBIT Sharpe Ratio of -0.38. The chart below compares the historical Sharpe Ratios of XBIO and XBIT, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	XBIO	XBIT	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.09	-0.38	+0.47
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.31	-0.48	+0.18
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.34	-0.15	-0.19
Sharpe Ratio (All Time) Calculated using the full available price history	-0.32	-0.23	-0.09

Correlation

The correlation between XBIO and XBIT is 0.07, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

XBIO vs. XBIT - Dividend Comparison

Neither XBIO nor XBIT has paid dividends to shareholders.

	TTM	2025	2024	2023	2022	2021
XBIO Xenetic Biosciences, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
XBIT XBiotech Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	22.46%

Drawdowns

XBIO vs. XBIT - Drawdown Comparison

The maximum XBIO drawdown since its inception was -99.95%, which is greater than XBIT's maximum drawdown of -92.67%. Use the drawdown chart below to compare losses from any high point for XBIO and XBIT.

Drawdown Indicators

	XBIO	XBIT	Difference
Max Drawdown Largest peak-to-trough decline	-99.95%	-92.67%	-7.28%
Max Drawdown (1Y) Largest decline over 1 year	-80.50%	-39.43%	-41.07%
Max Drawdown (5Y) Largest decline over 5 years	-96.19%	-87.21%	-8.98%
Max Drawdown (10Y) Largest decline over 10 years	-99.83%	-90.72%	-9.11%
Current Drawdown Current decline from peak	-99.93%	-91.38%	-8.55%
Average Drawdown Average peak-to-trough decline	-91.28%	-69.78%	-21.50%
Ulcer Index Depth and duration of drawdowns from previous peaks	52.52%	23.84%	+28.68%

Volatility

XBIO vs. XBIT - Volatility Comparison

Xenetic Biosciences, Inc. (XBIO) has a higher volatility of 30.65% compared to XBiotech Inc. (XBIT) at 7.77%. This indicates that XBIO's price experiences larger fluctuations and is considered to be riskier than XBIT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	XBIO	XBIT	Difference
Volatility (1M) Calculated over the trailing 1-month period	30.65%	7.77%	+22.88%
Volatility (6M) Calculated over the trailing 6-month period	116.33%	40.36%	+75.97%
Volatility (1Y) Calculated over the trailing 1-year period	169.13%	59.87%	+109.26%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	108.22%	64.08%	+44.14%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	134.13%	75.92%	+58.21%

Financials