XBIT vs. VHT

Last updated Apr 1, 2026

Compare and contrast key facts about XBiotech Inc. (XBIT) and Vanguard Health Care ETF (VHT).

VHT is a passively managed fund by Vanguard that tracks the performance of the MSCI US Investable Market Health Care 25/50 Index. It was launched on Jan 26, 2004.

Performance

XBIT vs. VHT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in XBiotech Inc. (XBIT) and Vanguard Health Care ETF (VHT). The values are adjusted to include any dividend payments, if applicable.

XBIT vs. VHT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
XBIT XBiotech Inc.	-1.67%	-39.49%	-1.25%	13.96%	-68.46%	-17.46%	-16.15%	267.42%	28.93%	-61.07%
VHT Vanguard Health Care ETF	-5.04%	15.46%	2.66%	2.52%	-5.60%	20.57%	18.29%	21.87%	5.58%	23.26%

Returns By Period

In the year-to-date period, XBIT achieves a -1.67% return, which is significantly higher than VHT's -5.04% return. Over the past 10 years, XBIT has underperformed VHT with an annualized return of -11.70%, while VHT has yielded a comparatively higher 9.72% annualized return.

XBIT

• 1D: 3.52%
• 1M: 3.98%
• YTD: -1.67%
• 6M: -11.65%
• 1Y: -27.47%
• 3Y*: -12.01%
• 5Y*: -30.75%
• 10Y*: -11.70%

VHT

• 1D: 2.24%
• 1M: -7.50%
• YTD: -5.04%
• 6M: 5.91%
• 1Y: 4.70%
• 3Y*: 6.16%
• 5Y*: 5.09%
• 10Y*: 9.72%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

XBIT vs. VHT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

XBIT

XBIT Risk / Return Rank: 22
XBIT Sharpe Ratio Rank: 21
XBIT Sortino Ratio Rank: 22
XBIT Omega Ratio Rank: 23
XBIT Calmar Ratio Rank: 21
XBIT Martin Ratio Rank: 24

VHT

VHT Risk / Return Rank: 21
VHT Sharpe Ratio Rank: 20
VHT Sortino Ratio Rank: 20
VHT Omega Ratio Rank: 19
VHT Calmar Ratio Rank: 25
VHT Martin Ratio Rank: 21

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

XBIT vs. VHT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for XBiotech Inc. (XBIT) and Vanguard Health Care ETF (VHT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	XBIT	VHT	Difference
Sharpe ratio Return per unit of total volatility	-0.46	0.27	-0.73
Sortino ratio Return per unit of downside risk	-0.38	0.49	-0.87
Omega ratio Gain probability vs. loss probability	0.96	1.06	-0.11
Calmar ratio Return relative to maximum drawdown	-0.61	0.51	-1.13
Martin ratio Return relative to average drawdown	-1.02	1.09	-2.11
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

XBIT vs. VHT - Sharpe Ratio Comparison

The current XBIT Sharpe Ratio is -0.46, which is lower than the VHT Sharpe Ratio of 0.27. The chart below compares the historical Sharpe Ratios of XBIT and VHT, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	XBIT	VHT	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.46	0.27	-0.73
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.48	0.34	-0.83
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.15	0.58	-0.73
Sharpe Ratio (All Time) Calculated using the full available price history	-0.23	0.56	-0.79

Correlation

The correlation between XBIT and VHT is 0.26, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

XBIT vs. VHT - Dividend Comparison

XBIT has not paid dividends to shareholders, while VHT's dividend yield for the trailing twelve months is around 1.73%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
XBIT XBiotech Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	22.46%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
VHT Vanguard Health Care ETF	1.73%	1.61%	1.53%	1.36%	1.33%	1.14%	1.21%	1.89%	1.38%	1.31%	1.45%	1.22%

Drawdowns

XBIT vs. VHT - Drawdown Comparison

The maximum XBIT drawdown since its inception was -92.67%, which is greater than VHT's maximum drawdown of -39.12%. Use the drawdown chart below to compare losses from any high point for XBIT and VHT.

Drawdown Indicators

	XBIT	VHT	Difference
Max Drawdown Largest peak-to-trough decline	-92.67%	-39.12%	-53.55%
Max Drawdown (1Y) Largest decline over 1 year	-39.43%	-10.40%	-29.03%
Max Drawdown (5Y) Largest decline over 5 years	-87.21%	-17.71%	-69.50%
Max Drawdown (10Y) Largest decline over 10 years	-90.72%	-28.85%	-61.87%
Current Drawdown Current decline from peak	-91.34%	-8.05%	-83.29%
Average Drawdown Average peak-to-trough decline	-69.77%	-5.98%	-63.79%
Ulcer Index Depth and duration of drawdowns from previous peaks	23.77%	4.96%	+18.81%

Volatility

XBIT vs. VHT - Volatility Comparison

XBiotech Inc. (XBIT) has a higher volatility of 7.80% compared to Vanguard Health Care ETF (VHT) at 5.10%. This indicates that XBIT's price experiences larger fluctuations and is considered to be riskier than VHT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	XBIT	VHT	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.80%	5.10%	+2.70%
Volatility (6M) Calculated over the trailing 6-month period	40.38%	10.28%	+30.10%
Volatility (1Y) Calculated over the trailing 1-year period	60.04%	17.61%	+42.43%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	64.08%	14.85%	+49.23%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	75.93%	16.94%	+58.99%