XBIO vs. PFE
XBIO (Xenetic Biosciences, Inc.) and PFE (Pfizer Inc.) are both stocks. Both are in the Healthcare sector — XBIO in Biotechnology, PFE in Drug Manufacturers - General. Over the past 10 years, XBIO returned -42.83%/yr vs 1.94%/yr for PFE. At a 0.07 correlation, their price movements are largely independent.
Performance
XBIO vs. PFE - Performance Comparison
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Returns By Period
In the year-to-date period, XBIO achieves a 55.76% return, which is significantly higher than PFE's 6.05% return. Over the past 10 years, XBIO has underperformed PFE with an annualized return of -42.83%, while PFE has yielded a comparatively higher 1.94% annualized return.
XBIO
- 1D
- 2.11%
- 1M
- 13.80%
- YTD
- 55.76%
- 6M
- 37.96%
- 1Y
- 2.74%
- 3Y*
- 1.95%
- 5Y*
- -31.79%
- 10Y*
- -42.83%
PFE
- 1D
- -0.31%
- 1M
- -1.36%
- YTD
- 6.05%
- 6M
- 5.00%
- 1Y
- 16.52%
- 3Y*
- -7.06%
- 5Y*
- -3.26%
- 10Y*
- 1.94%
XBIO vs. PFE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
XBIO Xenetic Biosciences, Inc. | 55.76% | -45.61% | 15.65% | 21.01% | -77.90% | -36.76% | 41.67% | -92.68% | -14.54% | -55.37% |
PFE Pfizer Inc. | 6.05% | 0.65% | -2.22% | -41.26% | -10.41% | 66.70% | 3.07% | -6.91% | 24.82% | 15.90% |
Correlation
The correlation between XBIO and PFE is 0.11, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.11 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.09 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.07 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.07 |
Correlation (All Time) Calculated using the full available price history since Jul 1, 2014 | 0.07 |
Fundamentals
XBIO:
$7.74M
PFE:
$146.43B
XBIO:
-$1.17
PFE:
$1.31
XBIO:
2.03
PFE:
2.30
XBIO:
1.11
PFE:
1.63
XBIO:
$3.19M
PFE:
$63.32B
XBIO:
$2.38M
PFE:
$43.91B
XBIO:
-$2.37M
PFE:
$16.94B
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Return for Risk
XBIO vs. PFE — Risk / Return Rank
XBIO
PFE
XBIO vs. PFE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Xenetic Biosciences, Inc. (XBIO) and Pfizer Inc. (PFE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| XBIO | PFE | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 0.02 | 0.70 | -0.68 |
Sortino ratioReturn per unit of downside risk | 1.59 | 1.20 | +0.38 |
Omega ratioGain probability vs. loss probability | 1.19 | 1.14 | +0.05 |
Calmar ratioReturn relative to maximum drawdown | 0.16 | 1.43 | -1.27 |
Martin ratioReturn relative to average drawdown | 0.21 | 2.97 | -2.76 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| XBIO | PFE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.02 | 0.70 | -0.68 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.30 | -0.13 | -0.17 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | -0.32 | 0.08 | -0.40 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.31 | 0.23 | -0.54 |
Drawdowns
XBIO vs. PFE - Drawdown Comparison
The maximum XBIO drawdown since its inception was -99.95%, which is greater than PFE's maximum drawdown of -58.96%. Use the drawdown chart below to compare losses from any high point for XBIO and PFE.
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Drawdown Indicators
| XBIO | PFE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.95% | -58.96% | -40.99% |
Max Drawdown (1Y)Largest decline over 1 year | -80.50% | -11.47% | -69.03% |
Max Drawdown (3Y)Largest decline over 3 years | -80.50% | -40.75% | -39.75% |
Max Drawdown (5Y)Largest decline over 5 years | -96.19% | -58.96% | -37.23% |
Max Drawdown (10Y)Largest decline over 10 years | -99.78% | -58.96% | -40.82% |
Current DrawdownCurrent decline from peak | -99.91% | -47.05% | -52.86% |
Average DrawdownAverage peak-to-trough decline | -91.40% | -17.68% | -73.72% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 59.71% | 5.51% | +54.20% |
Volatility
XBIO vs. PFE - Volatility Comparison
Xenetic Biosciences, Inc. (XBIO) has a higher volatility of 12.74% compared to Pfizer Inc. (PFE) at 4.00%. This indicates that XBIO's price experiences larger fluctuations and is considered to be riskier than PFE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| XBIO | PFE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 12.74% | 4.00% | +8.74% |
Volatility (6M)Calculated over the trailing 6-month period | 51.15% | 14.73% | +36.42% |
Volatility (1Y)Calculated over the trailing 1-year period | 168.93% | 23.84% | +145.09% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 108.03% | 25.49% | +82.54% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 134.15% | 23.88% | +110.27% |
Dividends
XBIO vs. PFE - Dividend Comparison
XBIO has not paid dividends to shareholders, while PFE's dividend yield for the trailing twelve months is around 6.73%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
PFE Pfizer Inc. | 6.73% | 6.91% | 6.33% | 5.70% | 3.12% | 2.64% | 3.92% | 3.68% | 3.12% | 3.53% | 3.69% | 3.47% |
XBIO Xenetic Biosciences, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
XBIO vs. PFE - Financials Comparison
This section allows you to compare key financial metrics between Xenetic Biosciences, Inc. and Pfizer Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
XBIO vs. PFE - Profitability Comparison
XBIO - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Xenetic Biosciences, Inc. reported a gross profit of 0.00 and revenue of 806.92K. Therefore, the gross margin over that period was 0.0%.
PFE - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Pfizer Inc. reported a gross profit of 9.72B and revenue of 14.45B. Therefore, the gross margin over that period was 67.3%.
XBIO - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Xenetic Biosciences, Inc. reported an operating income of -502.12K and revenue of 806.92K, resulting in an operating margin of -62.2%.
PFE - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Pfizer Inc. reported an operating income of 4.03B and revenue of 14.45B, resulting in an operating margin of 27.9%.
XBIO - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Xenetic Biosciences, Inc. reported a net income of -456.38K and revenue of 806.92K, resulting in a net margin of -56.6%.
PFE - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Pfizer Inc. reported a net income of 2.69B and revenue of 14.45B, resulting in a net margin of 18.6%.
Frequently Asked Questions
XBIO and PFE have a correlation of 0.11, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
XBIO has higher volatility (12.74%) compared to PFE (4.00%). In terms of maximum drawdown, XBIO dropped -99.95% vs PFE's -58.96%.
PFE currently has the higher Sharpe Ratio (0.70 vs 0.02), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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