XBIO vs. VT

Last updated Jul 11, 2026

XBIO (Xenetic Biosciences, Inc.) is a stock, while VT (Vanguard Total World Stock ETF) is Global Equities fund tracking the FTSE Global All Cap Index. Over the past 10 years, XBIO returned -41.53%/yr vs 12.58%/yr for VT. At a 0.13 correlation, their price movements are largely independent.

Performance

XBIO vs. VT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Xenetic Biosciences, Inc. (XBIO) and Vanguard Total World Stock ETF (VT). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, XBIO achieves a 26.04% return, which is significantly higher than VT's 12.41% return. Over the past 10 years, XBIO has underperformed VT with an annualized return of -41.53%, while VT has yielded a comparatively higher 12.58% annualized return.

XBIO

• 1D: -1.44%
• 1M: -14.53%
• 6M: 23.98%
• YTD: 26.04%
• 1Y: -31.28%
• 3Y*: -13.12%
• 5Y*: -32.42%
• 10Y*: -41.53%

VT

• 1D: 0.40%
• 1M: 1.22%
• 6M: 9.67%
• YTD: 12.41%
• 1Y: 24.11%
• 3Y*: 19.87%
• 5Y*: 10.78%
• 10Y*: 12.58%

*Multi-year figures are annualized to reflect compound growth (CAGR)

XBIO vs. VT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
XBIO Xenetic Biosciences, Inc.	26.04%	-45.61%	15.65%	21.01%	-77.90%	-36.76%	41.67%	-92.68%	-14.54%	-55.37%
VT Vanguard Total World Stock ETF	12.41%	22.43%	16.49%	22.02%	-18.00%	18.27%	16.59%	26.81%	-9.76%	24.50%

Correlation

The correlation between XBIO and VT is 0.23, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.23
Correlation (3Y) Calculated over the trailing 3-year period	0.16
Correlation (5Y) Calculated over the trailing 5-year period	0.20
Correlation (10Y) Calculated over the trailing 10-year period	0.14
Correlation (All Time) Calculated using the full available price history since Jun 30, 2014	0.13

Return for Risk

XBIO vs. VT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

XBIO

XBIO Risk / Return Rank: 44
XBIO Sharpe Ratio Rank: 38
XBIO Sortino Ratio Rank: 58
XBIO Omega Ratio Rank: 56
XBIO Calmar Ratio Rank: 33
XBIO Martin Ratio Rank: 37

VT

VT Risk / Return Rank: 66
VT Sharpe Ratio Rank: 66
VT Sortino Ratio Rank: 65
VT Omega Ratio Rank: 66
VT Calmar Ratio Rank: 61
VT Martin Ratio Rank: 71

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

XBIO vs. VT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Xenetic Biosciences, Inc. (XBIO) and Vanguard Total World Stock ETF (VT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	XBIO	VT	Difference
Sharpe ratio: Return per unit of total volatility	-0.17	1.73	-1.91
Sortino ratio: Return per unit of downside risk	0.93	2.41	-1.48
Omega ratio: Gain probability vs. loss probability	1.11	1.31	-0.20
Calmar ratio: Return relative to maximum drawdown	-0.36	2.44	-2.80
Martin ratio: Return relative to average drawdown	-0.45	10.41	-10.86

XBIO vs. VT - Sharpe Ratio Comparison

The current XBIO Sharpe Ratio is -0.17, which is lower than the VT Sharpe Ratio of 1.73. The chart below compares the historical Sharpe Ratios of XBIO and VT, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

XBIO vs. VT - Drawdown Comparison

The maximum XBIO drawdown since its inception was -99.95%, which is greater than VT's maximum drawdown of -50.27%. Use the drawdown chart below to compare losses from any high point for XBIO and VT.

Drawdown Indicators

	XBIO	VT	Difference
Max Drawdown Largest peak-to-trough decline	-99.95%	-50.27%	-49.68%
Max Drawdown (1Y) Largest decline over 1 year	-80.50%	-9.67%	-70.83%
Max Drawdown (3Y) Largest decline over 3 years	-80.50%	-16.51%	-63.99%
Max Drawdown (5Y) Largest decline over 5 years	-96.19%	-26.38%	-69.81%
Max Drawdown (10Y) Largest decline over 10 years	-99.72%	-34.24%	-65.48%
Current Drawdown Current decline from peak	-99.93%	-0.72%	-99.21%
Average Drawdown Average peak-to-trough decline	-91.44%	-6.99%	-84.45%
Ulcer Index Depth and duration of drawdowns from previous peaks	63.70%	2.26%	+61.44%

Volatility

XBIO vs. VT - Volatility Comparison

Xenetic Biosciences, Inc. (XBIO) has a higher volatility of 17.59% compared to Vanguard Total World Stock ETF (VT) at 4.90%. This indicates that XBIO's price experiences larger fluctuations and is considered to be riskier than VT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	XBIO	VT	Difference
Volatility (1M) Calculated over the trailing 1-month period	17.59%	4.90%	+12.69%
Volatility (6M) Calculated over the trailing 6-month period	51.42%	11.41%	+40.01%
Volatility (1Y) Calculated over the trailing 1-year period	165.55%	13.61%	+151.94%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	107.83%	16.19%	+91.64%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	134.14%	17.15%	+116.99%

Dividends

XBIO vs. VT - Dividend Comparison

XBIO has not paid dividends to shareholders, while VT's dividend yield for the trailing twelve months is around 1.58%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
VT Vanguard Total World Stock ETF	1.58%	1.82%	1.95%	2.08%	2.20%	1.82%	1.66%	2.32%	2.53%	2.11%	2.39%	2.45%
XBIO Xenetic Biosciences, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both XBIO and VT in my portfolio?

XBIO and VT have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, XBIO or VT?

XBIO has higher volatility (17.59%) compared to VT (4.90%). In terms of maximum drawdown, XBIO dropped -99.95% vs VT's -50.27%.

Which has better risk-adjusted returns?

VT currently has the higher Sharpe Ratio (1.73 vs -0.17), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.