TSLL vs. TLSA
TSLL (Direxion Daily TSLA Bull 2X ETF) is Leveraged Equities fund actively managed by Direxion, while TLSA (Tiziana Life Sciences PLC) is a stock. Over the past 3 years, TSLL returned -7.94%/yr vs 15.87%/yr for TLSA. At a 0.09 correlation, their price movements are largely independent.
Performance
TSLL vs. TLSA - Performance Comparison
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Returns By Period
In the year-to-date period, TSLL achieves a -39.31% return, which is significantly lower than TLSA's -24.83% return.
TSLL
- 1D
- -3.38%
- 1M
- -24.58%
- YTD
- -39.31%
- 6M
- -48.10%
- 1Y
- -11.43%
- 3Y*
- -7.94%
- 5Y*
- —
- 10Y*
- —
TLSA
- 1D
- -3.45%
- 1M
- -24.32%
- YTD
- -24.83%
- 6M
- -26.80%
- 1Y
- -29.11%
- 3Y*
- 15.87%
- 5Y*
- -14.84%
- 10Y*
- —
TSLL vs. TLSA - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
TSLL Direxion Daily TSLA Bull 2X ETF | -39.31% | -26.80% | 99.63% | 139.86% | -74.99% |
TLSA Tiziana Life Sciences PLC | -24.83% | 114.02% | 24.32% | -6.43% | -18.01% |
Correlation
The correlation between TSLL and TLSA is 0.15, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.15 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.07 |
Correlation (All Time) Calculated using the full available price history since Aug 9, 2022 | 0.09 |
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Return for Risk
TSLL vs. TLSA — Risk / Return Rank
TSLL
TLSA
TSLL vs. TLSA - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Direxion Daily TSLA Bull 2X ETF (TSLL) and Tiziana Life Sciences PLC (TLSA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| TSLL | TLSA | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.24 | ||
| Sortino ratioReturn per unit of downside risk | +0.50 | ||
| Omega ratioGain probability vs. loss probability | 1.05 | 0.99 | +0.06 |
| Calmar ratioReturn relative to maximum drawdown | -0.21 | -0.51 | +0.30 |
| Martin ratioReturn relative to average drawdown | -0.42 | -0.80 | +0.38 |
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Drawdowns
TSLL vs. TLSA - Drawdown Comparison
The maximum TSLL drawdown since its inception was -82.88%, smaller than the maximum TLSA drawdown of -94.03%. Use the drawdown chart below to compare losses from any high point for TSLL and TLSA.
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Drawdown Indicators
| TSLL | TLSA | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -82.88% | -94.03% | +11.15% |
Max Drawdown (1Y)Largest decline over 1 year | -54.75% | -56.80% | +2.05% |
Max Drawdown (3Y)Largest decline over 3 years | -82.88% | -56.80% | -26.08% |
Max Drawdown (5Y)Largest decline over 5 years | — | -83.32% | — |
Current DrawdownCurrent decline from peak | -69.35% | -83.98% | +14.63% |
Average DrawdownAverage peak-to-trough decline | -53.93% | -70.36% | +16.43% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 27.51% | 36.36% | -8.85% |
Volatility
TSLL vs. TLSA - Volatility Comparison
Direxion Daily TSLA Bull 2X ETF (TSLL) has a higher volatility of 28.32% compared to Tiziana Life Sciences PLC (TLSA) at 19.69%. This indicates that TSLL's price experiences larger fluctuations and is considered to be riskier than TLSA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TSLL | TLSA | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 28.32% | 19.69% | +8.63% |
Volatility (6M)Calculated over the trailing 6-month period | 56.74% | 53.43% | +3.31% |
Volatility (1Y)Calculated over the trailing 1-year period | 87.53% | 79.29% | +8.24% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 106.85% | 92.69% | +14.16% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 106.85% | 112.52% | -5.67% |
Dividends
TSLL vs. TLSA - Dividend Comparison
TSLL's dividend yield for the trailing twelve months is around 8.63%, while TLSA has not paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
TLSA Tiziana Life Sciences PLC | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
TSLL Direxion Daily TSLA Bull 2X ETF | 8.63% | 5.00% | 2.47% | 4.44% | 1.57% |
Frequently Asked Questions
TSLL and TLSA have a correlation of 0.15, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TSLL has higher volatility (28.32%) compared to TLSA (19.69%). In terms of maximum drawdown, TSLL dropped -82.88% vs TLSA's -94.03%.
TSLL currently has the higher Sharpe Ratio (-0.13 vs -0.37), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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