TLSA vs. TSLY
TLSA (Tiziana Life Sciences PLC) is a stock, while TSLY (YieldMax TSLA Option Income Strategy ETF) is Options Trading fund actively managed by YieldMax. Over the past 3 years, TLSA returned 17.81%/yr vs -0.29%/yr for TSLY. Their 0.06 correlation means their historical movements had little consistent relationship.
Performance
TLSA vs. TSLY - Performance Comparison
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Returns By Period
In the year-to-date period, TLSA achieves a -30.87% return, which is significantly lower than TSLY's -24.18% return.
TLSA
- 1D
- 6.19%
- 1M
- -21.37%
- 6M
- -31.79%
- YTD
- -30.87%
- 1Y
- -56.72%
- 3Y*
- 17.81%
- 5Y*
- -13.52%
- 10Y*
- —
- ALL TIME*
- -8.85%
TSLY
- 1D
- 0.62%
- 1M
- -18.26%
- 6M
- -22.89%
- YTD
- -24.18%
- 1Y
- 7.14%
- 3Y*
- -0.29%
- 5Y*
- —
- 10Y*
- —
- ALL TIME*
- 5.31%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $257.99K | $292.00K | $299.82K | |
| $13.88M | $12.88M | $17.43M |
TLSA vs. TSLY - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
TLSA Tiziana Life Sciences PLC | -30.87% | 114.02% | 24.32% | -6.43% | -6.50% |
TSLY YieldMax TSLA Option Income Strategy ETF | -24.18% | 13.62% | 27.83% | 50.69% | -27.09% |
Correlation
The correlation between TLSA and TSLY is 0.12, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.12 |
Correlation (3Y) Balances recent behavior with more history. | 0.06 |
Correlation (All Time) Calculated using the full available price history since Nov 23, 2022 | 0.06 |
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Return for Risk
TLSA vs. TSLY — Risk / Return Rank
TLSA
TSLY
TLSA vs. TSLY - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Tiziana Life Sciences PLC (TLSA) and YieldMax TSLA Option Income Strategy ETF (TSLY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| TLSA | TSLY | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.89 | ||
| Sortino ratioReturn per unit of downside risk | -1.53 | ||
| Omega ratioGain probability vs. loss probability | 0.89 | 1.06 | -0.17 |
| Calmar ratioReturn relative to maximum drawdown | -0.93 | 0.18 | -1.10 |
| Martin ratioReturn relative to average drawdown | -1.49 | 0.52 | -2.01 |
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Drawdowns
TLSA vs. TSLY - Drawdown Comparison
The maximum TLSA drawdown since its inception was -94.03%, which is greater than TSLY's maximum drawdown of -49.52%. Use the drawdown chart below to compare losses from any high point for TLSA and TSLY.
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Drawdown Indicators
| TLSA | TSLY | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -94.03% | -49.52% | -44.51% |
Max Drawdown (1Y)Largest decline over 1 year | -63.72% | -31.78% | -31.94% |
Max Drawdown (3Y)Largest decline over 3 years | -64.30% | -49.52% | -14.78% |
Max Drawdown (5Y)Largest decline over 5 years | -79.95% | — | — |
Current DrawdownCurrent decline from peak | -85.26% | -29.10% | -56.16% |
Average DrawdownAverage peak-to-trough decline | -70.54% | -19.79% | -50.75% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 40.33% | 10.80% | +29.53% |
Volatility
TLSA vs. TSLY - Volatility Comparison
Tiziana Life Sciences PLC (TLSA) has a higher volatility of 29.58% compared to YieldMax TSLA Option Income Strategy ETF (TSLY) at 18.70%. This indicates that TLSA's price experiences larger fluctuations and is considered to be riskier than TSLY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TLSA | TSLY | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 29.58% | 18.70% | +10.88% |
Volatility (6M)Calculated over the trailing 6-month period | 55.75% | 29.69% | +26.06% |
Volatility (1Y)Calculated over the trailing 1-year period | 79.08% | 38.29% | +40.79% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 93.09% | 46.00% | +47.09% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 112.27% | 46.00% | +66.27% |
Dividends
TLSA vs. TSLY - Dividend Comparison
TLSA has not paid dividends to shareholders, while TSLY's dividend yield for the trailing twelve months is around 111.92%.
| Position | TTM | 2025 | 2024 | 2023 |
|---|---|---|---|---|
TLSA Tiziana Life Sciences PLC | 0.00% | 0.00% | 0.00% | 0.00% |
TSLY YieldMax TSLA Option Income Strategy ETF | 111.92% | 91.19% | 82.30% | 76.47% |
Frequently Asked Questions
TLSA and TSLY have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TLSA has higher volatility (29.58%) compared to TSLY (18.70%). In terms of maximum drawdown, TLSA dropped -94.03% vs TSLY's -49.52%.
TSLY currently has the higher Sharpe Ratio (0.15 vs -0.75), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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