TLSA vs. TSLY
TLSA (Tiziana Life Sciences PLC) is a stock, while TSLY (YieldMax TSLA Option Income Strategy ETF) is Options Trading fund actively managed by YieldMax. Over the past 3 years, TLSA returned 21.25%/yr vs 7.64%/yr for TSLY. At a 0.06 correlation, their price movements are largely independent.
Performance
TLSA vs. TSLY - Performance Comparison
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Returns By Period
In the year-to-date period, TLSA achieves a -17.45% return, which is significantly lower than TSLY's -4.21% return.
TLSA
- 1D
- -2.38%
- 1M
- 11.82%
- 6M
- -13.99%
- YTD
- -17.45%
- 1Y
- -16.89%
- 3Y*
- 21.25%
- 5Y*
- -10.98%
- 10Y*
- —
TSLY
- 1D
- -0.04%
- 1M
- 1.06%
- 6M
- -3.60%
- YTD
- -4.21%
- 1Y
- 32.01%
- 3Y*
- 7.64%
- 5Y*
- —
- 10Y*
- —
TLSA vs. TSLY - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
TLSA Tiziana Life Sciences PLC | -17.45% | 114.02% | 24.32% | -6.43% | -6.50% |
TSLY YieldMax TSLA Option Income Strategy ETF | -4.21% | 13.62% | 27.83% | 50.69% | -27.09% |
Correlation
The correlation between TLSA and TSLY is 0.14, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.14 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.06 |
Correlation (All Time) Calculated using the full available price history since Nov 23, 2022 | 0.06 |
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Return for Risk
TLSA vs. TSLY — Risk / Return Rank
TLSA
TSLY
TLSA vs. TSLY - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Tiziana Life Sciences PLC (TLSA) and YieldMax TSLA Option Income Strategy ETF (TSLY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| TLSA | TSLY | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.13 | ||
| Sortino ratioReturn per unit of downside risk | -1.16 | ||
| Omega ratioGain probability vs. loss probability | 1.03 | 1.17 | -0.14 |
| Calmar ratioReturn relative to maximum drawdown | -0.29 | 1.54 | -1.83 |
| Martin ratioReturn relative to average drawdown | -0.43 | 3.58 | -4.01 |
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Drawdowns
TLSA vs. TSLY - Drawdown Comparison
The maximum TLSA drawdown since its inception was -94.03%, which is greater than TSLY's maximum drawdown of -49.52%. Use the drawdown chart below to compare losses from any high point for TLSA and TSLY.
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Drawdown Indicators
| TLSA | TSLY | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -94.03% | -49.52% | -44.51% |
Max Drawdown (1Y)Largest decline over 1 year | -56.80% | -21.64% | -35.16% |
Max Drawdown (3Y)Largest decline over 3 years | -56.80% | -49.52% | -7.28% |
Max Drawdown (5Y)Largest decline over 5 years | -80.42% | — | — |
Current DrawdownCurrent decline from peak | -82.40% | -10.44% | -71.96% |
Average DrawdownAverage peak-to-trough decline | -70.43% | -19.76% | -50.67% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 37.70% | 9.31% | +28.39% |
Volatility
TLSA vs. TSLY - Volatility Comparison
Tiziana Life Sciences PLC (TLSA) has a higher volatility of 20.68% compared to YieldMax TSLA Option Income Strategy ETF (TSLY) at 14.40%. This indicates that TLSA's price experiences larger fluctuations and is considered to be riskier than TSLY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TLSA | TSLY | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 20.68% | 14.40% | +6.28% |
Volatility (6M)Calculated over the trailing 6-month period | 54.58% | 25.81% | +28.77% |
Volatility (1Y)Calculated over the trailing 1-year period | 79.52% | 36.25% | +43.27% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 92.90% | 45.65% | +47.25% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 112.36% | 45.65% | +66.71% |
Dividends
TLSA vs. TSLY - Dividend Comparison
TLSA has not paid dividends to shareholders, while TSLY's dividend yield for the trailing twelve months is around 83.40%.
| Position | TTM | 2025 | 2024 | 2023 |
|---|---|---|---|---|
TLSA Tiziana Life Sciences PLC | 0.00% | 0.00% | 0.00% | 0.00% |
TSLY YieldMax TSLA Option Income Strategy ETF | 83.40% | 91.19% | 82.30% | 76.47% |
Frequently Asked Questions
TLSA and TSLY have a correlation of 0.14, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TLSA has higher volatility (20.68%) compared to TSLY (14.40%). In terms of maximum drawdown, TLSA dropped -94.03% vs TSLY's -49.52%.
TSLY currently has the higher Sharpe Ratio (0.93 vs -0.21), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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