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Tiziana Life Sciences PLC (TLSA)
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN

BMG889121031

CUSIP

88875G101

IPO Date

Mar 24, 2000

Highlights

Market Cap

$162.42M

EPS (TTM)

-$0.11

Year Range

$0.63 - $1.91

Target Price

$3.00

Short %

1.17%

Short Ratio

1.88

Share Price Chart


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Compare to other instruments

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Performance

Performance Chart


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S&P 500

Returns By Period

Tiziana Life Sciences PLC (TLSA) returned 95.35% year-to-date (YTD) and 44.68% over the past 12 months.


TLSA

YTD

95.35%

1M

0.00%

6M

42.78%

1Y

44.68%

3Y*

26.96%

5Y*

-12.29%

10Y*

N/A

^GSPC (Benchmark)

YTD

0.51%

1M

6.15%

6M

-2.00%

1Y

12.92%

3Y*

12.68%

5Y*

14.19%

10Y*

10.85%

*Annualized

Monthly Returns

The table below presents the monthly returns of TLSA, with color gradation from worst to best to easily spot seasonal factors. Returns are adjusted for dividends.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2025-1.61%88.32%-16.28%25.93%0.00%95.35%
2024-5.18%-9.49%-5.53%44.67%52.24%-8.09%16.43%-6.54%-4.00%1.56%-2.31%-26.91%24.32%
20237.77%-13.63%95.94%-28.08%8.28%-19.84%-4.61%11.85%-9.23%-0.86%-9.81%-5.08%-6.43%
2022-13.54%-21.67%61.51%-2.86%-34.85%12.19%-1.92%4.32%2.25%-10.90%-5.28%-9.08%-37.66%
202182.18%-18.21%-7.97%-5.78%-9.96%-0.21%-8.36%-22.07%-12.05%6.85%-19.23%-23.81%-52.05%
2020-11.91%-9.91%-4.80%35.80%138.62%-2.87%172.19%-49.50%-5.67%14.71%-34.82%-18.88%87.03%
2019-9.40%-11.41%1.16%36.37%-14.79%2.42%-2.37%-10.66%-1.92%-0.65%-11.72%-0.05%-27.52%
2018-5.99%-5.09%-10.78%
Go deeper with the Portfolio Analysis tool — backtest performance, assess risk, compare to benchmarks, and more

Risk-Adjusted Performance

Risk-Adjusted Performance Rank

The current rank of TLSA is 71, indicating average performance compared to other stocks on our website. Here’s a breakdown of how it compares using common performance measures.


The Risk-Adjusted Performance Rank of TLSA is 7171
Overall Rank
The Sharpe Ratio Rank of TLSA is 6565
Sharpe Ratio Rank
The Sortino Ratio Rank of TLSA is 7575
Sortino Ratio Rank
The Omega Ratio Rank of TLSA is 7171
Omega Ratio Rank
The Calmar Ratio Rank of TLSA is 7373
Calmar Ratio Rank
The Martin Ratio Rank of TLSA is 6868
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

Risk-Adjusted Performance Indicators

The charts below present risk-adjusted performance metrics for Tiziana Life Sciences PLC (TLSA) and compare them to a chosen benchmark (^GSPC). These indicators evaluate an investment's returns against its associated risks.


The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

Tiziana Life Sciences PLC Sharpe ratios as of May 31, 2025 (values are recalculated daily):

  • 1-Year: 0.40
  • 5-Year: -0.12
  • All Time: -0.03

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

The chart below shows the rolling Sharpe ratio of Tiziana Life Sciences PLC compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time.


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Go to the full Sharpe Ratio tool to analyze any stock or portfolio. Customize time frames, set your own risk-free rate, and more

Dividends

Dividend History


Tiziana Life Sciences PLC doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Tiziana Life Sciences PLC. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Tiziana Life Sciences PLC was 93.98%, occurring on Mar 27, 2024. The portfolio has not yet recovered.

The current Tiziana Life Sciences PLC drawdown is 80.37%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-93.98%Aug 3, 2020919Mar 27, 2024
-68.27%Nov 23, 2018280Feb 24, 202058May 15, 2020338
-28.11%Jul 21, 20203Jul 23, 20205Jul 30, 20208
-21.46%Jun 2, 20208Jun 11, 202016Jul 6, 202024
-19.49%May 19, 20202May 20, 20203May 26, 20205
Go to the full Drawdowns tool for more analysis options, including inflation-adjusted drawdowns, and more

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Tiziana Life Sciences PLC over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Earnings Per Share

The chart presents the Earnings Per Share (EPS) performance of Tiziana Life Sciences PLC, comparing actual results with analytics estimates. In the past quarter, the company did not meet analyst expectations for EPS, resulting in a surprise of -200.0%.


-0.25-0.20-0.15-0.10-0.050.00AprilJulyOctober2021AprilJulyOctober2022AprilJuly
-0.05
0
Actual
Estimate

Valuation

The Valuation section provides an overview of how Tiziana Life Sciences PLC is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for TLSA relative to other companies in the Biotechnology industry. Currently, TLSA has a P/S ratio of 0.0. This P/S ratio is low compared to the industry average. It may indicate that the stock is undervalued relative to its revenue, or that the market expects slower growth or lower margins.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for TLSA in comparison with other companies in the Biotechnology industry. Currently, TLSA has a P/B value of 41.0. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items