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Tiziana Life Sciences PLC (TLSA)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
BMG889121031
CUSIP
88875G101
IPO Date
Mar 24, 2000

Highlights

Market Cap
$68.34M
Enterprise Value
$61.31M
EPS (TTM)
-$0.53
Gross Profit (TTM)
-$316.00K
EBITDA (TTM)
-$38.66M
Year Range
$0.73 - $2.60
ROA (TTM)
-188.12%
ROE (TTM)
-339.38%

Share Price Chart


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Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Tiziana Life Sciences PLC, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

Tiziana Life Sciences PLC (TLSA) has returned -21.48% so far this year and 8.33% over the past 12 months.


Tiziana Life Sciences PLC

1D
-5.65%
1M
-19.31%
YTD
-21.48%
6M
-45.83%
1Y
8.33%
3Y*
2.34%
5Y*
-15.71%
10Y*

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Nov 20, 2018, TLSA's average daily return is +0.22%, while the average monthly return is +3.54%. At this rate, your investment would double in approximately 1.7 years.

Historically, 31% of months were positive and 69% were negative. The best month was Jul 2020 with a return of +172.1%, while the worst month was Aug 2020 at -49.5%. The longest winning streak lasted 2 consecutive months, and the longest losing streak was 8 months.

On a daily basis, TLSA closed higher 44% of trading days. The best single day was Mar 11, 2020 with a return of +95.5%, while the worst single day was Mar 13, 2020 at -36.5%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
20261.34%-3.97%-19.31%-21.48%
2025-1.61%88.32%-16.28%25.93%0.00%16.18%58.23%-27.60%19.34%-11.11%-6.25%-17.22%114.02%
2024-5.18%-9.49%-5.53%44.66%52.25%-8.09%16.43%-6.54%-4.00%1.56%-2.56%-26.72%24.32%
20237.77%-13.63%95.94%-28.08%8.28%-19.84%-4.61%11.85%-9.23%-0.86%-9.81%-5.08%-6.43%
2022-13.54%-21.67%61.51%-2.86%-34.85%12.19%-1.92%4.32%2.25%-10.90%-5.28%-9.08%-37.66%
202182.18%-18.21%-7.97%-5.78%-9.96%-0.21%-9.17%-22.07%-12.05%6.85%-19.23%-23.81%-52.48%

Benchmark Metrics

Tiziana Life Sciences PLC has an annualized alpha of 65.70%, beta of 0.31, and R² of 0.00 versus S&P 500 Index. Calculated based on daily prices since November 21, 2018.

  • This stock participated in 37.54% of S&P 500 Index downside but only 2.50% of its upside — more exposed to losses than it benefited from rallies.
  • Beta of 0.31 may look defensive, but with R² of 0.00 this stock is largely uncorrelated with S&P 500 Index — low beta reflects independence, not downside protection. See the Volatility section for a true picture of this stock's risk.
  • R² of 0.00 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
65.70%
Beta
0.31
0.00
Upside Capture
2.50%
Downside Capture
37.54%

Return for Risk

Risk / Return Rank

TLSA ranks 45 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


TLSA Risk / Return Rank: 4545
Overall Rank
TLSA Sharpe Ratio Rank: 4444
Sharpe Ratio Rank
TLSA Sortino Ratio Rank: 5252
Sortino Ratio Rank
TLSA Omega Ratio Rank: 4646
Omega Ratio Rank
TLSA Calmar Ratio Rank: 4242
Calmar Ratio Rank
TLSA Martin Ratio Rank: 4242
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Tiziana Life Sciences PLC (TLSA) and compare them to a chosen benchmark (S&P 500 Index).


TLSABenchmarkDifference

Sharpe ratio

Return per unit of total volatility

0.09

0.90

-0.80

Sortino ratio

Return per unit of downside risk

0.87

1.39

-0.51

Omega ratio

Gain probability vs. loss probability

1.09

1.21

-0.12

Calmar ratio

Return relative to maximum drawdown

0.08

1.40

-1.32

Martin ratio

Return relative to average drawdown

0.16

6.61

-6.45

Explore TLSA risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


Tiziana Life Sciences PLC doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Tiziana Life Sciences PLC. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Tiziana Life Sciences PLC was 94.03%, occurring on Mar 27, 2024. The portfolio has not yet recovered.

The current Tiziana Life Sciences PLC drawdown is 83.26%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-94.03%Aug 3, 2020919Mar 27, 2024
-68.27%Nov 23, 2018313Feb 24, 202058May 15, 2020371
-28.1%Jul 21, 20203Jul 23, 20205Jul 30, 20208
-21.46%Jun 2, 20208Jun 11, 202016Jul 6, 202024
-19.49%May 19, 20202May 20, 20203May 26, 20205

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Tiziana Life Sciences PLC over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Tiziana Life Sciences PLC is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for TLSA in comparison with other companies in the Biotechnology industry. Currently, TLSA has a P/B value of 7.4. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items