TSHA vs. AXGN
TSHA (Taysha Gene Therapies, Inc.) and AXGN (AxoGen, Inc.) are both stocks. Both are in the Healthcare sector — TSHA in Biotechnology, AXGN in Medical Devices. Over the past 5 years, TSHA returned -23.63%/yr vs 15.47%/yr for AXGN. At a 0.23 correlation, their price movements are largely independent.
Performance
TSHA vs. AXGN - Performance Comparison
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Returns By Period
In the year-to-date period, TSHA achieves a 18.73% return, which is significantly lower than AXGN's 37.34% return.
TSHA
- 1D
- 1.71%
- 1M
- 18.94%
- YTD
- 18.73%
- 6M
- 11.43%
- 1Y
- 165.45%
- 3Y*
- 114.68%
- 5Y*
- -23.63%
- 10Y*
- —
AXGN
- 1D
- 0.25%
- 1M
- 9.90%
- YTD
- 37.34%
- 6M
- 37.29%
- 1Y
- 361.97%
- 3Y*
- 71.00%
- 5Y*
- 15.47%
- 10Y*
- 21.87%
TSHA vs. AXGN - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|---|
TSHA Taysha Gene Therapies, Inc. | 18.73% | 217.92% | -2.26% | -21.68% | -80.60% | -56.10% | 19.28% |
AXGN AxoGen, Inc. | 37.34% | 98.60% | 141.29% | -31.56% | 6.51% | -47.65% | 47.69% |
Correlation
The correlation between TSHA and AXGN is 0.12, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.12 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.16 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.24 |
Correlation (All Time) Calculated using the full available price history since Sep 24, 2020 | 0.24 |
The correlation between TSHA and AXGN shifts across timeframes, from 0.12 (1 year) to 0.24 (5 years), reflecting how their relationship changes across market environments.
Fundamentals
TSHA:
$2.39B
AXGN:
$2.32B
TSHA:
-$0.39
AXGN:
-$0.66
TSHA:
292.29
AXGN:
8.97
TSHA:
11.30
AXGN:
9.47
TSHA:
$7.47M
AXGN:
$238.11M
TSHA:
$6.89M
AXGN:
$178.61M
TSHA:
-$130.51M
AXGN:
$5.69M
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Return for Risk
TSHA vs. AXGN — Risk / Return Rank
TSHA
AXGN
TSHA vs. AXGN - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Taysha Gene Therapies, Inc. (TSHA) and AxoGen, Inc. (AXGN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| TSHA | AXGN | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -4.90 | ||
| Sortino ratioReturn per unit of downside risk | -2.87 | ||
| Omega ratioGain probability vs. loss probability | 1.36 | 1.76 | -0.40 |
| Calmar ratioReturn relative to maximum drawdown | 5.35 | 18.90 | -13.55 |
| Martin ratioReturn relative to average drawdown | 11.14 | 65.69 | -54.55 |
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Drawdowns
TSHA vs. AXGN - Drawdown Comparison
The maximum TSHA drawdown since its inception was -98.14%, roughly equal to the maximum AXGN drawdown of -98.49%. Use the drawdown chart below to compare losses from any high point for TSHA and AXGN.
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Drawdown Indicators
| TSHA | AXGN | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.14% | -98.49% | +0.35% |
Max Drawdown (1Y)Largest decline over 1 year | -31.13% | -19.30% | -11.83% |
Max Drawdown (3Y)Largest decline over 3 years | -72.90% | -61.02% | -11.88% |
Max Drawdown (5Y)Largest decline over 5 years | -97.76% | -83.69% | -14.07% |
Max Drawdown (10Y)Largest decline over 10 years | — | -93.54% | — |
Current DrawdownCurrent decline from peak | -79.43% | -19.59% | -59.84% |
Average DrawdownAverage peak-to-trough decline | -76.85% | -64.83% | -12.02% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 14.91% | 5.54% | +9.37% |
Volatility
TSHA vs. AXGN - Volatility Comparison
Taysha Gene Therapies, Inc. (TSHA) has a higher volatility of 15.00% compared to AxoGen, Inc. (AXGN) at 11.38%. This indicates that TSHA's price experiences larger fluctuations and is considered to be riskier than AXGN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TSHA | AXGN | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 15.00% | 11.38% | +3.62% |
Volatility (6M)Calculated over the trailing 6-month period | 49.27% | 33.36% | +15.91% |
Volatility (1Y)Calculated over the trailing 1-year period | 87.56% | 53.70% | +33.86% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 136.69% | 64.07% | +72.62% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 130.29% | 62.09% | +68.20% |
Dividends
TSHA vs. AXGN - Dividend Comparison
Neither TSHA nor AXGN has paid dividends to shareholders.
Financials
TSHA vs. AXGN - Financials Comparison
This section allows you to compare key financial metrics between Taysha Gene Therapies, Inc. and AxoGen, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
TSHA and AXGN have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TSHA has higher volatility (15.00%) compared to AXGN (11.38%). In terms of maximum drawdown, TSHA dropped -98.14% vs AXGN's -98.49%.
AXGN currently has the higher Sharpe Ratio (6.81 vs 1.91), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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