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AXGN vs. STOK
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

AXGN vs. STOK - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in AxoGen, Inc. (AXGN) and Stoke Therapeutics, Inc. (STOK). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, AXGN achieves a 39.72% return, which is significantly higher than STOK's -6.87% return.


AXGN

1D
8.34%
1M
-0.35%
6M
30.58%
YTD
39.72%
1Y
260.93%
3Y*
75.78%
5Y*
18.83%
10Y*
18.28%
ALL TIME*
7.01%

STOK

1D
2.43%
1M
-9.60%
6M
-3.93%
YTD
-6.87%
1Y
128.97%
3Y*
69.04%
5Y*
2.06%
10Y*
ALL TIME*
1.17%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$52.56M$54.51M$52.29M
$25.25M$22.28M$23.90M

AXGN vs. STOK - Yearly Performance Comparison


2026 (YTD)2025202420232022202120202019
AXGN
AxoGen, Inc.
39.72%98.60%141.29%-31.56%6.51%-47.65%0.06%-8.40%
STOK
Stoke Therapeutics, Inc.
-6.87%187.76%109.70%-43.01%-61.53%-61.26%118.68%4.08%

Correlation

The correlation between AXGN and STOK is 0.18, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.18

Correlation (3Y)
Balances recent behavior with more history.

0.24

Correlation (5Y)
Shows whether the relationship held over a longer period.

0.29

Correlation (All Time)
Calculated using the full available price history since Jun 19, 2019

0.28

The correlation between AXGN and STOK shifts across timeframes, from 0.18 (1 year) to 0.29 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

AXGN:

$2.46B

STOK:

$1.84B

EPS

AXGN:

-$0.68

STOK:

-$3.38

PS Ratio

AXGN:

9.00

STOK:

65.92

PB Ratio

AXGN:

9.52

STOK:

5.65

Total Revenue (TTM)

AXGN:

$251.17M

STOK:

$27.59M

Gross Profit (TTM)

AXGN:

$187.27M

STOK:

$15.17M

EBITDA (TTM)

AXGN:

-$14.77M

STOK:

-$206.50M

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Return for Risk

AXGN vs. STOK — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

AXGN
AXGN Risk / Return Rank: 9999
Overall Rank
AXGN Sharpe Ratio Rank: 9999
Sharpe Ratio Rank
AXGN Sortino Ratio Rank: 9898
Sortino Ratio Rank
AXGN Omega Ratio Rank: 9898
Omega Ratio Rank
AXGN Calmar Ratio Rank: 9999
Calmar Ratio Rank
AXGN Martin Ratio Rank: 9999
Martin Ratio Rank

STOK
STOK Risk / Return Rank: 8989
Overall Rank
STOK Sharpe Ratio Rank: 9191
Sharpe Ratio Rank
STOK Sortino Ratio Rank: 9090
Sortino Ratio Rank
STOK Omega Ratio Rank: 8888
Omega Ratio Rank
STOK Calmar Ratio Rank: 8989
Calmar Ratio Rank
STOK Martin Ratio Rank: 8888
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

AXGN vs. STOK - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for AxoGen, Inc. (AXGN) and Stoke Therapeutics, Inc. (STOK). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


AXGNSTOKDifference
Sharpe ratioReturn per unit of total volatility

+2.80

Sortino ratioReturn per unit of downside risk

+2.07

Omega ratioGain probability vs. loss probability

1.61

1.35

+0.26

Calmar ratioReturn relative to maximum drawdown

13.61

3.49

+10.12

Martin ratioReturn relative to average drawdown

40.64

8.82

+31.82

AXGN vs. STOK - Sharpe Ratio Comparison

The current AXGN Sharpe Ratio is 4.84, which is higher than the STOK Sharpe Ratio of 2.04. The chart below compares the historical Sharpe Ratios of AXGN and STOK, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

AXGN vs. STOK - Drawdown Comparison

The maximum AXGN drawdown since its inception was -98.49%, roughly equal to the maximum STOK drawdown of -95.17%. Use the drawdown chart below to compare losses from any high point for AXGN and STOK.


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Drawdown Indicators


AXGNSTOKDifference

Max Drawdown

Largest peak-to-trough decline

-98.49%

-95.17%

-3.32%

Max Drawdown (1Y)

Largest decline over 1 year

-19.30%

-37.16%

+17.86%

Max Drawdown (3Y)

Largest decline over 3 years

-57.13%

-66.32%

+9.19%

Max Drawdown (5Y)

Largest decline over 5 years

-81.35%

-89.03%

+7.68%

Max Drawdown (10Y)

Largest decline over 10 years

-93.54%

Current Drawdown

Current decline from peak

-18.19%

-57.66%

+39.47%

Average Drawdown

Average peak-to-trough decline

-64.71%

-62.15%

-2.56%

Ulcer Index

Depth and duration of drawdowns from previous peaks

6.45%

14.68%

-8.23%

Volatility

AXGN vs. STOK - Volatility Comparison

AxoGen, Inc. (AXGN) has a higher volatility of 14.40% compared to Stoke Therapeutics, Inc. (STOK) at 12.49%. This indicates that AXGN's price experiences larger fluctuations and is considered to be riskier than STOK based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


AXGNSTOKDifference

Volatility (1M)

Calculated over the trailing 1-month period

14.40%

12.49%

+1.91%

Volatility (6M)

Calculated over the trailing 6-month period

34.65%

35.83%

-1.18%

Volatility (1Y)

Calculated over the trailing 1-year period

54.40%

63.66%

-9.26%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

64.35%

80.70%

-16.35%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

61.87%

79.73%

-17.86%

Dividends

AXGN vs. STOK - Dividend Comparison

Neither AXGN nor STOK has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

AXGN vs. STOK - Financials Comparison

This section allows you to compare key financial metrics between AxoGen, Inc. and Stoke Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

Frequently Asked Questions


AXGN and STOK have a correlation of 0.18, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

AXGN has higher volatility (14.40%) compared to STOK (12.49%). In terms of maximum drawdown, AXGN dropped -98.49% vs STOK's -95.17%.

AXGN currently has the higher Sharpe Ratio (4.84 vs 2.04), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for AXGN and STOK

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