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Taysha Gene Therapies, Inc. (TSHA)
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN

US8776191061

CUSIP

877619106

IPO Date

Sep 24, 2020

Highlights

Market Cap

$579.59M

EPS (TTM)

-$0.34

Total Revenue (TTM)

$7.22M

Gross Profit (TTM)

$5.25M

EBITDA (TTM)

-$85.67M

Year Range

$1.05 - $4.32

Target Price

$7.05

Short %

14.78%

Short Ratio

10.16

Share Price Chart


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Compare to other instruments

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.


Performance

Performance Chart


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Returns By Period

Taysha Gene Therapies, Inc. (TSHA) returned 56.07% year-to-date (YTD) and -12.62% over the past 12 months.


TSHA

YTD

56.07%

1M

117.74%

6M

31.07%

1Y

-12.62%

5Y*

N/A

10Y*

N/A

^GSPC (Benchmark)

YTD

1.30%

1M

12.79%

6M

1.49%

1Y

12.35%

5Y*

15.12%

10Y*

10.89%

*Annualized

Monthly Returns

The table below presents the monthly returns of TSHA, with color gradation from worst to best to easily spot seasonal factors. Returns are adjusted for dividends.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2025-13.29%6.67%-13.12%39.57%39.18%56.07%
2024-14.12%107.89%-9.18%-15.33%41.15%-34.69%-1.34%1.36%-10.27%-15.92%91.72%-46.60%-2.26%
2023-27.43%-38.41%-20.99%-2.88%-9.81%-5.44%1.82%375.48%-1.25%-25.95%-24.79%0.57%-21.68%
2022-31.76%-19.87%2.35%-43.87%-30.33%45.88%9.41%-22.36%-38.92%-10.88%28.49%2.26%-80.60%
2021-2.03%-1.58%-20.67%27.14%-12.82%-5.78%-18.44%14.98%-6.34%-16.00%-17.01%-10.25%-56.10%
2020-6.90%-7.14%8.75%17.33%10.31%

Risk-Adjusted Performance

Risk-Adjusted Performance Rank

The current rank of TSHA is 55, indicating average performance compared to other stocks on our website. Here’s a breakdown of how it compares using common performance measures.


The Risk-Adjusted Performance Rank of TSHA is 5555
Overall Rank
The Sharpe Ratio Rank of TSHA is 4444
Sharpe Ratio Rank
The Sortino Ratio Rank of TSHA is 6262
Sortino Ratio Rank
The Omega Ratio Rank of TSHA is 6262
Omega Ratio Rank
The Calmar Ratio Rank of TSHA is 5353
Calmar Ratio Rank
The Martin Ratio Rank of TSHA is 5252
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

Risk-Adjusted Performance Indicators

The charts below present risk-adjusted performance metrics for Taysha Gene Therapies, Inc. (TSHA) and compare them to a chosen benchmark (^GSPC). These indicators evaluate an investment's returns against its associated risks.


The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

Taysha Gene Therapies, Inc. Sharpe ratios as of May 18, 2025 (values are recalculated daily):

  • 1-Year: -0.13
  • All Time: -0.27

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

The chart below shows the rolling Sharpe ratio of Taysha Gene Therapies, Inc. compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time. For deeper analysis or to customize the calculation, use the Sharpe ratio tool.


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Dividends

Dividend History


Taysha Gene Therapies, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Taysha Gene Therapies, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Taysha Gene Therapies, Inc. was 98.14%, occurring on Jun 28, 2023. The portfolio has not yet recovered.

The current Taysha Gene Therapies, Inc. drawdown is 91.50%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-98.14%Jan 21, 2021613Jun 28, 2023
-21.78%Sep 28, 202050Dec 7, 202012Dec 23, 202062
-10.74%Dec 24, 20208Jan 6, 20216Jan 14, 202114

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Taysha Gene Therapies, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Earnings Per Share

The chart presents the Earnings Per Share (EPS) performance of Taysha Gene Therapies, Inc., comparing actual results with analytics estimates. The company has exceeded analyst expectations for EPS in the past quarter, achieving a 17.1% positive surprise.


-1.00-0.500.000.501.00JulyOctober2021AprilJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025
-0.07
-0.09
Actual
Estimate

Valuation

The Valuation section provides an overview of how Taysha Gene Therapies, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for TSHA relative to other companies in the Biotechnology industry. Currently, TSHA has a P/S ratio of 80.2. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for TSHA in comparison with other companies in the Biotechnology industry. Currently, TSHA has a P/B value of 10.5. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items