TRDA vs. CI

Last updated Aug 1, 2026

TRDA (Entrada Therapeutics, Inc.) and CI (The Cigna Group) are both stocks. Both are in the Healthcare sector — TRDA in Biotechnology, CI in Healthcare Plans. Over the past 3 years, TRDA returned -26.27%/yr vs -0.02%/yr for CI. Their 0.05 correlation means their historical movements had little consistent relationship.

Performance

TRDA vs. CI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Entrada Therapeutics, Inc. (TRDA) and The Cigna Group (CI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, TRDA achieves a -33.95% return, which is significantly lower than CI's 2.54% return.

TRDA

• 1D: 0.30%
• 1M: -12.05%
• 6M: -40.65%
• YTD: -33.95%
• 1Y: 17.07%
• 3Y*: -26.27%
• 5Y*: —
• 10Y*: —
• ALL TIME*: -24.91%

CI

• 1D: -2.99%
• 1M: -3.03%
• 6M: 2.96%
• YTD: 2.54%
• 1Y: 8.77%
• 3Y*: -0.02%
• 5Y*: 5.92%
• 10Y*: 9.54%
• ALL TIME*: 10.94%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
CI The Cigna Group	$460.57M	$474.33M	$477.27M
TRDA Entrada Therapeutics, Inc.	$3.07M	$2.97M	$3.45M

TRDA vs. CI - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
TRDA Entrada Therapeutics, Inc.	-33.95%	-40.54%	14.58%	11.61%	-21.03%	-35.40%
CI The Cigna Group	2.54%	1.72%	-6.27%	-7.97%	46.68%	6.97%

Correlation

The correlation between TRDA and CI is 0.01, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.01
Correlation (3Y) Balances recent behavior with more history.	0.06
Correlation (All Time) Calculated using the full available price history since Oct 29, 2021	0.05

Fundamentals

Market Cap TRDA : $263.59M CI : $73.82B
EPS TRDA : -$4.00 CI : $24.16
PS Ratio TRDA : 49.18 CI : 0.26
PB Ratio TRDA : 1.05 CI : 1.73
Total Revenue (TTM) TRDA : $5.74M CI : $282.38B
Gross Profit (TTM) TRDA : -$34.38M CI : $17.96B
EBITDA (TTM) TRDA : -$172.23M CI : $9.16B

Return for Risk

TRDA vs. CI — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

TRDA

TRDA Risk / Return Rank: 55
TRDA Sharpe Ratio Rank: 52
TRDA Sortino Ratio Rank: 57
TRDA Omega Ratio Rank: 64
TRDA Calmar Ratio Rank: 51
TRDA Martin Ratio Rank: 51

CI

CI Risk / Return Rank: 51
CI Sharpe Ratio Rank: 54
CI Sortino Ratio Rank: 46
CI Omega Ratio Rank: 47
CI Calmar Ratio Rank: 53
CI Martin Ratio Rank: 54

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

TRDA vs. CI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Entrada Therapeutics, Inc. (TRDA) and The Cigna Group (CI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	TRDA	CI	Difference
Sharpe ratio: Return per unit of total volatility	0.18	0.21	-0.03
Sortino ratio: Return per unit of downside risk	0.89	0.48	+0.41
Omega ratio: Gain probability vs. loss probability	1.16	1.07	+0.09
Calmar ratio: Return relative to maximum drawdown	0.24	0.31	-0.07
Martin ratio: Return relative to average drawdown	0.54	0.74	-0.20

TRDA vs. CI - Sharpe Ratio Comparison

The current TRDA Sharpe Ratio is 0.18, which is comparable to the CI Sharpe Ratio of 0.21. The chart below compares the historical Sharpe Ratios of TRDA and CI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

TRDA vs. CI - Drawdown Comparison

The maximum TRDA drawdown since its inception was -85.66%, roughly equal to the maximum CI drawdown of -84.34%. Use the drawdown chart below to compare losses from any high point for TRDA and CI.

Drawdown Indicators

	TRDA	CI	Difference
Max Drawdown Largest peak-to-trough decline	-85.66%	-84.34%	-1.32%
Max Drawdown (1Y) Largest decline over 1 year	-64.75%	-21.41%	-43.34%
Max Drawdown (3Y) Largest decline over 3 years	-76.75%	-32.10%	-44.65%
Max Drawdown (5Y) Largest decline over 5 years	—	-32.10%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-42.47%	—
Current Drawdown Current decline from peak	-80.60%	-21.16%	-59.44%
Average Drawdown Average peak-to-trough decline	-63.26%	-18.82%	-44.44%
Ulcer Index Depth and duration of drawdowns from previous peaks	28.89%	9.02%	+19.87%

Volatility

TRDA vs. CI - Volatility Comparison

Entrada Therapeutics, Inc. (TRDA) has a higher volatility of 20.66% compared to The Cigna Group (CI) at 10.65%. This indicates that TRDA's price experiences larger fluctuations and is considered to be riskier than CI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	TRDA	CI	Difference
Volatility (1M) Calculated over the trailing 1-month period	20.66%	10.65%	+10.01%
Volatility (6M) Calculated over the trailing 6-month period	97.02%	20.43%	+76.59%
Volatility (1Y) Calculated over the trailing 1-year period	86.69%	33.83%	+52.86%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	89.50%	28.73%	+60.77%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	89.50%	30.70%	+58.80%

Dividends

TRDA vs. CI - Dividend Comparison

TRDA has not paid dividends to shareholders, while CI's dividend yield for the trailing twelve months is around 2.20%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CI The Cigna Group	2.20%	2.19%	2.03%	1.64%	1.35%	1.74%	0.02%	0.02%	0.02%	0.02%	0.03%	0.03%
TRDA Entrada Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both TRDA and CI in my portfolio?

TRDA and CI have a correlation of 0.01, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, TRDA or CI?

TRDA has higher volatility (20.66%) compared to CI (10.65%). In terms of maximum drawdown, TRDA dropped -85.66% vs CI's -84.34%.

Which has better risk-adjusted returns?

CI currently has the higher Sharpe Ratio (0.21 vs 0.18), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.