TRDA vs. VOO
TRDA (Entrada Therapeutics, Inc.) is a stock, while VOO (Vanguard S&P 500 ETF) is S&P 500 fund tracking the S&P 500 Index. Over the past 3 years, TRDA returned -21.10%/yr vs 20.78%/yr for VOO. At a 0.26 correlation, their price movements are largely independent.
Performance
TRDA vs. VOO - Performance Comparison
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Returns By Period
In the year-to-date period, TRDA achieves a -29.57% return, which is significantly lower than VOO's 8.19% return.
TRDA
- 1D
- 2.40%
- 1M
- 10.37%
- YTD
- -29.57%
- 6M
- -31.89%
- 1Y
- 2.84%
- 3Y*
- -21.10%
- 5Y*
- —
- 10Y*
- —
VOO
- 1D
- -1.42%
- 1M
- -1.34%
- YTD
- 8.19%
- 6M
- 7.24%
- 1Y
- 23.69%
- 3Y*
- 20.78%
- 5Y*
- 13.13%
- 10Y*
- 15.61%
TRDA vs. VOO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
TRDA Entrada Therapeutics, Inc. | -29.57% | -40.54% | 14.58% | 11.61% | -21.03% | -35.40% |
VOO Vanguard S&P 500 ETF | 8.19% | 17.82% | 24.98% | 26.32% | -18.17% | 3.98% |
Correlation
The correlation between TRDA and VOO is 0.29, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.29 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.32 |
Correlation (All Time) Calculated using the full available price history since Oct 29, 2021 | 0.26 |
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Return for Risk
TRDA vs. VOO — Risk / Return Rank
TRDA
VOO
TRDA vs. VOO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Entrada Therapeutics, Inc. (TRDA) and Vanguard S&P 500 ETF (VOO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| TRDA | VOO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.88 | ||
| Sortino ratioReturn per unit of downside risk | -1.88 | ||
| Omega ratioGain probability vs. loss probability | 1.13 | 1.35 | -0.22 |
| Calmar ratioReturn relative to maximum drawdown | 0.04 | 2.67 | -2.63 |
| Martin ratioReturn relative to average drawdown | 0.11 | 11.96 | -11.85 |
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Drawdowns
TRDA vs. VOO - Drawdown Comparison
The maximum TRDA drawdown since its inception was -85.66%, which is greater than VOO's maximum drawdown of -33.99%. Use the drawdown chart below to compare losses from any high point for TRDA and VOO.
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Drawdown Indicators
| TRDA | VOO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -85.66% | -33.99% | -51.67% |
Max Drawdown (1Y)Largest decline over 1 year | -64.75% | -8.90% | -55.85% |
Max Drawdown (3Y)Largest decline over 3 years | -76.75% | -18.69% | -58.06% |
Max Drawdown (5Y)Largest decline over 5 years | — | -24.52% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.99% | — |
Current DrawdownCurrent decline from peak | -79.31% | -3.14% | -76.17% |
Average DrawdownAverage peak-to-trough decline | -62.86% | -3.68% | -59.18% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 25.24% | 1.99% | +23.25% |
Volatility
TRDA vs. VOO - Volatility Comparison
Entrada Therapeutics, Inc. (TRDA) has a higher volatility of 18.16% compared to Vanguard S&P 500 ETF (VOO) at 4.83%. This indicates that TRDA's price experiences larger fluctuations and is considered to be riskier than VOO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TRDA | VOO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 18.16% | 4.83% | +13.33% |
Volatility (6M)Calculated over the trailing 6-month period | 95.59% | 9.82% | +85.77% |
Volatility (1Y)Calculated over the trailing 1-year period | 85.55% | 12.46% | +73.09% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 89.86% | 16.91% | +72.95% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 89.86% | 18.02% | +71.84% |
Dividends
TRDA vs. VOO - Dividend Comparison
TRDA has not paid dividends to shareholders, while VOO's dividend yield for the trailing twelve months is around 1.05%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
TRDA Entrada Therapeutics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
VOO Vanguard S&P 500 ETF | 1.05% | 1.13% | 1.24% | 1.46% | 1.69% | 1.25% | 1.54% | 1.88% | 2.06% | 1.78% | 2.02% | 2.10% |
Frequently Asked Questions
TRDA and VOO have a correlation of 0.29, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TRDA has higher volatility (18.16%) compared to VOO (4.83%). In terms of maximum drawdown, TRDA dropped -85.66% vs VOO's -33.99%.
VOO currently has the higher Sharpe Ratio (1.91 vs 0.03), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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