TDOC.TO vs. XDNA.TO
TDOC.TO (TD Global Healthcare Leaders Index ETF) and XDNA.TO (iShares Genomics Immunology and Healthcare Index ETF) are both Health & Biotech Equities funds. TDOC.TO is actively managed, while XDNA.TO is passively managed. Over the past 3 years, TDOC.TO returned 6.84%/yr vs 14.77%/yr for XDNA.TO. At a 0.22 correlation, their price movements are largely independent.
Performance
TDOC.TO vs. XDNA.TO - Performance Comparison
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Returns By Period
In the year-to-date period, TDOC.TO achieves a 0.57% return, which is significantly lower than XDNA.TO's 29.19% return.
TDOC.TO
- 1D
- 0.00%
- 1M
- 3.81%
- 6M
- -3.26%
- YTD
- 0.57%
- 1Y
- 12.75%
- 3Y*
- 6.84%
- 5Y*
- 5.10%
- 10Y*
- —
XDNA.TO
- 1D
- -0.02%
- 1M
- 10.93%
- 6M
- 18.06%
- YTD
- 29.19%
- 1Y
- 60.37%
- 3Y*
- 14.77%
- 5Y*
- —
- 10Y*
- —
TDOC.TO vs. XDNA.TO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
TDOC.TO TD Global Healthcare Leaders Index ETF | 0.57% | 8.36% | 10.24% | 1.71% | 7.65% |
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 29.19% | 12.10% | 5.54% | -7.84% | -14.85% |
Correlation
The correlation between TDOC.TO and XDNA.TO is 0.29, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.29 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.23 |
Correlation (All Time) Calculated using the full available price history since May 4, 2022 | 0.22 |
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Return for Risk
TDOC.TO vs. XDNA.TO — Risk / Return Rank
TDOC.TO
XDNA.TO
TDOC.TO vs. XDNA.TO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for TD Global Healthcare Leaders Index ETF (TDOC.TO) and iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| TDOC.TO | XDNA.TO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.46 | ||
| Sortino ratioReturn per unit of downside risk | -1.81 | ||
| Omega ratioGain probability vs. loss probability | 1.16 | 1.40 | -0.23 |
| Calmar ratioReturn relative to maximum drawdown | 1.09 | 7.02 | -5.93 |
| Martin ratioReturn relative to average drawdown | 2.58 | 16.10 | -13.52 |
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Drawdowns
TDOC.TO vs. XDNA.TO - Drawdown Comparison
The maximum TDOC.TO drawdown since its inception was -17.52%, smaller than the maximum XDNA.TO drawdown of -45.90%. Use the drawdown chart below to compare losses from any high point for TDOC.TO and XDNA.TO.
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Drawdown Indicators
| TDOC.TO | XDNA.TO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -17.52% | -45.90% | +28.38% |
Max Drawdown (1Y)Largest decline over 1 year | -11.77% | -8.64% | -3.13% |
Max Drawdown (3Y)Largest decline over 3 years | -12.66% | -28.29% | +15.63% |
Max Drawdown (5Y)Largest decline over 5 years | -17.52% | — | — |
Current DrawdownCurrent decline from peak | -4.61% | -6.85% | +2.24% |
Average DrawdownAverage peak-to-trough decline | -4.82% | -22.99% | +18.17% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.94% | 3.76% | +1.18% |
Volatility
TDOC.TO vs. XDNA.TO - Volatility Comparison
The current volatility for TD Global Healthcare Leaders Index ETF (TDOC.TO) is 5.09%, while iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO) has a volatility of 7.84%. This indicates that TDOC.TO experiences smaller price fluctuations and is considered to be less risky than XDNA.TO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TDOC.TO | XDNA.TO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 5.09% | 7.84% | -2.75% |
Volatility (6M)Calculated over the trailing 6-month period | 10.73% | 18.84% | -8.11% |
Volatility (1Y)Calculated over the trailing 1-year period | 14.24% | 25.64% | -11.40% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 13.07% | 25.42% | -12.35% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 12.93% | 25.42% | -12.49% |
Dividends
TDOC.TO vs. XDNA.TO - Dividend Comparison
TDOC.TO's dividend yield for the trailing twelve months is around 1.19%, more than XDNA.TO's 0.25% yield.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
TDOC.TO TD Global Healthcare Leaders Index ETF | 1.19% | 1.09% | 3.68% | 0.98% | 1.16% | 0.60% |
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 0.25% | 0.43% | 0.32% | 0.25% | 0.32% | 0.00% |
Frequently Asked Questions
TDOC.TO and XDNA.TO have a correlation of 0.29, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
They also come from different issuers: TD and iShares.
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