SEI vs. AXSM

Last updated Jun 9, 2026

SEI (Solaris Energy Infrastructure, Inc) and AXSM (Axsome Therapeutics, Inc.) are both stocks. SEI operates in Oil & Gas Equipment & Services (Energy), while AXSM operates in Biotechnology (Healthcare). Over the past 5 years, SEI returned 52.77%/yr vs 29.93%/yr for AXSM. At a 0.18 correlation, their price movements are largely independent.

Performance

SEI vs. AXSM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Solaris Energy Infrastructure, Inc (SEI) and Axsome Therapeutics, Inc. (AXSM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, SEI achieves a 57.74% return, which is significantly higher than AXSM's 28.75% return.

SEI

• 1D: 4.06%
• 1M: -0.85%
• YTD: 57.74%
• 6M: 35.54%
• 1Y: 143.14%
• 3Y*: 111.29%
• 5Y*: 52.77%
• 10Y*: —

AXSM

• 1D: 1.21%
• 1M: 8.17%
• YTD: 28.75%
• 6M: 59.35%
• 1Y: 110.12%
• 3Y*: 47.19%
• 5Y*: 29.93%
• 10Y*: 39.88%

*Multi-year figures are annualized to reflect compound growth (CAGR)

SEI vs. AXSM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
SEI Solaris Energy Infrastructure, Inc	57.74%	62.29%	277.66%	-15.75%	57.46%	-15.55%	-38.09%	19.10%	-43.06%	85.37%
AXSM Axsome Therapeutics, Inc.	28.75%	115.86%	6.31%	3.19%	104.16%	-53.63%	-21.18%	3,565.25%	-49.64%	34.94%

Correlation

The correlation between SEI and AXSM is 0.05, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.05
Correlation (3Y) Calculated over the trailing 3-year period	0.14
Correlation (5Y) Calculated over the trailing 5-year period	0.18
Correlation (All Time) Calculated using the full available price history since May 15, 2017	0.18

The correlation between SEI and AXSM shifts across timeframes, from 0.05 (1 year) to 0.18 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap SEI : $3.57B AXSM : $12.04B
EPS SEI : $1.03 AXSM : -$3.74
PS Ratio SEI : 4.71 AXSM : 16.71
PB Ratio SEI : 4.58 AXSM : 220.54
Total Revenue (TTM) SEI : $692.11M AXSM : $708.24M
Gross Profit (TTM) SEI : $235.28M AXSM : $655.82M
EBITDA (TTM) SEI : $249.65M AXSM : -$172.72M

Return for Risk

SEI vs. AXSM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SEI

SEI Risk / Return Rank: 88
SEI Sharpe Ratio Rank: 89
SEI Sortino Ratio Rank: 83
SEI Omega Ratio Rank: 81
SEI Calmar Ratio Rank: 93
SEI Martin Ratio Rank: 92

AXSM

AXSM Risk / Return Rank: 94
AXSM Sharpe Ratio Rank: 94
AXSM Sortino Ratio Rank: 95
AXSM Omega Ratio Rank: 93
AXSM Calmar Ratio Rank: 94
AXSM Martin Ratio Rank: 94

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

SEI vs. AXSM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Solaris Energy Infrastructure, Inc (SEI) and Axsome Therapeutics, Inc. (AXSM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	SEI	AXSM	Difference
Sharpe ratio: Return per unit of total volatility	1.96	2.65	-0.70
Sortino ratio: Return per unit of downside risk	2.45	4.01	-1.56
Omega ratio: Gain probability vs. loss probability	1.30	1.47	-0.17
Calmar ratio: Return relative to maximum drawdown	5.45	5.99	-0.54
Martin ratio: Return relative to average drawdown	13.72	17.16	-3.44
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

SEI vs. AXSM - Sharpe Ratio Comparison

The current SEI Sharpe Ratio is 1.96, which is comparable to the AXSM Sharpe Ratio of 2.65. The chart below compares the historical Sharpe Ratios of SEI and AXSM, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	SEI	AXSM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.96	2.65	-0.70
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.80	0.43	+0.37
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.44	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.43	0.40	+0.03

Drawdowns

SEI vs. AXSM - Drawdown Comparison

The maximum SEI drawdown since its inception was -79.49%, smaller than the maximum AXSM drawdown of -86.65%. Use the drawdown chart below to compare losses from any high point for SEI and AXSM.

Drawdown Indicators

	SEI	AXSM	Difference
Max Drawdown Largest peak-to-trough decline	-79.49%	-86.65%	+7.16%
Max Drawdown (1Y) Largest decline over 1 year	-26.43%	-18.50%	-7.93%
Max Drawdown (3Y) Largest decline over 3 years	-55.37%	-36.45%	-18.92%
Max Drawdown (5Y) Largest decline over 5 years	-55.37%	-72.91%	+17.54%
Max Drawdown (10Y) Largest decline over 10 years	—	-81.26%	—
Current Drawdown Current decline from peak	-7.95%	-0.35%	-7.60%
Average Drawdown Average peak-to-trough decline	-38.65%	-39.55%	+0.90%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.55%	6.56%	+3.99%

Volatility

SEI vs. AXSM - Volatility Comparison

Solaris Energy Infrastructure, Inc (SEI) has a higher volatility of 17.54% compared to Axsome Therapeutics, Inc. (AXSM) at 9.83%. This indicates that SEI's price experiences larger fluctuations and is considered to be riskier than AXSM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	SEI	AXSM	Difference
Volatility (1M) Calculated over the trailing 1-month period	17.54%	9.83%	+7.71%
Volatility (6M) Calculated over the trailing 6-month period	51.78%	32.98%	+18.80%
Volatility (1Y) Calculated over the trailing 1-year period	73.80%	41.79%	+32.01%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	66.56%	70.31%	-3.75%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	62.17%	90.68%	-28.51%

Dividends

SEI vs. AXSM - Dividend Comparison

SEI's dividend yield for the trailing twelve months is around 0.66%, while AXSM has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018
AXSM Axsome Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
SEI Solaris Energy Infrastructure, Inc	0.66%	1.04%	1.67%	5.65%	4.23%	6.41%	5.16%	2.89%	0.83%

Financials

SEI vs. AXSM - Profitability Comparison

The chart below illustrates the profitability comparison between Solaris Energy Infrastructure, Inc and Axsome Therapeutics, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

SEI - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Solaris Energy Infrastructure, Inc reported a gross profit of 72.72M and revenue of 196.24M. Therefore, the gross margin over that period was 37.1%.

AXSM - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Axsome Therapeutics, Inc. reported a gross profit of 176.48M and revenue of 191.20M. Therefore, the gross margin over that period was 92.3%.

SEI - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Solaris Energy Infrastructure, Inc reported an operating income of 50.56M and revenue of 196.24M, resulting in an operating margin of 25.8%.

AXSM - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Axsome Therapeutics, Inc. reported an operating income of -63.36M and revenue of 191.20M, resulting in an operating margin of -33.1%.

SEI - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Solaris Energy Infrastructure, Inc reported a net income of 21.44M and revenue of 196.24M, resulting in a net margin of 10.9%.

AXSM - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Axsome Therapeutics, Inc. reported a net income of -64.54M and revenue of 191.20M, resulting in a net margin of -33.8%.

Frequently Asked Questions

Can I hold both SEI and AXSM in my portfolio?

SEI and AXSM have a correlation of 0.05, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, SEI or AXSM?

SEI has higher volatility (17.54%) compared to AXSM (9.83%). In terms of maximum drawdown, SEI dropped -79.49% vs AXSM's -86.65%.

Which has better risk-adjusted returns?

AXSM currently has the higher Sharpe Ratio (2.65 vs 1.96), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.