SBIO vs. SLV
SBIO (ALPS Medical Breakthroughs ETF) and SLV (iShares Silver Trust) are both exchange-traded funds - SBIO is a Health & Biotech Equities fund tracking the S-Network Medical Breakthroughs Index, while SLV is a Silver fund tracking the LBMA Silver Price. Both are passively managed. Over the past 10 years, SBIO returned 10.96%/yr vs 10.57%/yr for SLV. At a 0.12 correlation, their price movements are largely independent. Both charge a 0.50% expense ratio.
Performance
SBIO vs. SLV - Performance Comparison
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Returns By Period
In the year-to-date period, SBIO achieves a 24.17% return, which is significantly higher than SLV's -20.86% return. Both investments have delivered pretty close results over the past 10 years, with SBIO having a 10.96% annualized return and SLV not far behind at 10.57%.
SBIO
- 1D
- -2.45%
- 1M
- 15.41%
- 6M
- 24.53%
- YTD
- 24.17%
- 1Y
- 93.61%
- 3Y*
- 27.21%
- 5Y*
- 6.86%
- 10Y*
- 10.96%
- ALL TIME*
- 9.19%
SLV
- 1D
- 0.39%
- 1M
- -14.33%
- 6M
- -37.08%
- YTD
- -20.86%
- 1Y
- 47.30%
- 3Y*
- 31.21%
- 5Y*
- 16.83%
- 10Y*
- 10.57%
- ALL TIME*
- 7.03%
SBIO vs. SLV - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
SBIO ALPS Medical Breakthroughs ETF | 24.17% | 55.07% | 3.81% | 8.68% | -28.08% | -17.55% | 21.17% | 50.30% | -11.81% | 45.67% |
SLV iShares Silver Trust | -20.86% | 144.66% | 20.89% | -1.09% | 2.37% | -12.45% | 47.30% | 14.88% | -9.19% | 5.82% |
Correlation
The correlation between SBIO and SLV is 0.17, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.17 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.20 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.18 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.15 |
Correlation (All Time) Calculated using the full available price history since Dec 31, 2014 | 0.12 |
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Return for Risk
SBIO vs. SLV — Risk / Return Rank
SBIO
SLV
SBIO vs. SLV - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for ALPS Medical Breakthroughs ETF (SBIO) and iShares Silver Trust (SLV). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| SBIO | SLV | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +2.29 | ||
| Sortino ratioReturn per unit of downside risk | +2.64 | ||
| Omega ratioGain probability vs. loss probability | 1.46 | 1.19 | +0.27 |
| Calmar ratioReturn relative to maximum drawdown | 7.44 | 0.91 | +6.53 |
| Martin ratioReturn relative to average drawdown | 20.36 | 1.85 | +18.51 |
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Drawdowns
SBIO vs. SLV - Drawdown Comparison
The maximum SBIO drawdown since its inception was -63.06%, smaller than the maximum SLV drawdown of -76.28%. Use the drawdown chart below to compare losses from any high point for SBIO and SLV.
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Drawdown Indicators
| SBIO | SLV | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -63.06% | -76.28% | +13.22% |
Max Drawdown (1Y)Largest decline over 1 year | -12.66% | -52.28% | +39.62% |
Max Drawdown (3Y)Largest decline over 3 years | -42.44% | -52.28% | +9.84% |
Max Drawdown (5Y)Largest decline over 5 years | -52.49% | -52.28% | -0.21% |
Max Drawdown (10Y)Largest decline over 10 years | -63.06% | -52.28% | -10.78% |
Current DrawdownCurrent decline from peak | -7.75% | -51.72% | +43.97% |
Average DrawdownAverage peak-to-trough decline | -28.20% | -44.67% | +16.47% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.61% | 25.64% | -21.03% |
Volatility
SBIO vs. SLV - Volatility Comparison
The current volatility for ALPS Medical Breakthroughs ETF (SBIO) is 11.36%, while iShares Silver Trust (SLV) has a volatility of 12.54%. This indicates that SBIO experiences smaller price fluctuations and is considered to be less risky than SLV based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| SBIO | SLV | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 11.36% | 12.54% | -1.18% |
Volatility (6M)Calculated over the trailing 6-month period | 24.09% | 56.50% | -32.41% |
Volatility (1Y)Calculated over the trailing 1-year period | 30.73% | 61.24% | -30.51% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 33.90% | 36.87% | -2.97% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 33.16% | 32.18% | +0.98% |
SBIO vs. SLV - Expense Ratio Comparison
Both SBIO and SLV have an expense ratio of 0.50%.
Dividends
SBIO vs. SLV - Dividend Comparison
Neither SBIO nor SLV has paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
SBIO ALPS Medical Breakthroughs ETF | 0.00% | 0.00% | 3.55% | 0.22% | 0.00% | 0.00% | 0.00% | 0.04% | 2.79% | 1.77% |
SLV iShares Silver Trust | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
SBIO and SLV have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SLV has higher volatility (12.54%) compared to SBIO (11.36%). In terms of maximum drawdown, SBIO dropped -63.06% vs SLV's -76.28%.
On 10-year performance, SBIO leads with 10.96% vs 10.57% for SLV. Both ETFs have the same 0.50% expense ratio. On volatility, SBIO has been the lower-risk option at 11.36%. The better choice depends on whether you care most about return, fees, risk, or income.
Over the 10-year period, SBIO has performed better with a 10.96% return vs 10.57%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.
SBIO and SLV have the same expense ratio: 0.50% per year.
SBIO and SLV have nearly identical dividend yields, around 0.00%.
SBIO is categorized as Health & Biotech Equities, while SLV is Silver. SBIO tracks S-Network Medical Breakthroughs Index, while SLV tracks LBMA Silver Price. They also come from different issuers: SS&C and iShares.
SBIO currently has the higher Sharpe Ratio (3.07 vs 0.78), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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