SBIO vs. QTUM
Compare and contrast key facts about ALPS Medical Breakthroughs ETF (SBIO) and Defiance Quantum ETF (QTUM).
SBIO and QTUM are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. SBIO is a passively managed fund by SS&C that tracks the performance of the S-Network Medical Breakthroughs Index. It was launched on Dec 31, 2014. QTUM is a passively managed fund by Defiance that tracks the performance of the BlueStar Machine Learning and Quantum Computing Index. It was launched on Sep 5, 2018. Both SBIO and QTUM are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.
Performance
SBIO vs. QTUM - Performance Comparison
Loading graphics...
SBIO vs. QTUM - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | |
|---|---|---|---|---|---|---|---|---|---|
SBIO ALPS Medical Breakthroughs ETF | 3.20% | 55.07% | 3.81% | 8.68% | -28.08% | -17.55% | 21.17% | 50.30% | -24.37% |
QTUM Defiance Quantum ETF | -0.14% | 36.65% | 50.54% | 39.86% | -28.80% | 35.18% | 42.05% | 47.99% | -19.02% |
Returns By Period
In the year-to-date period, SBIO achieves a 3.20% return, which is significantly higher than QTUM's -0.14% return.
SBIO
- 1D
- 0.99%
- 1M
- 3.89%
- YTD
- 3.20%
- 6M
- 36.23%
- 1Y
- 95.78%
- 3Y*
- 26.37%
- 5Y*
- 1.76%
- 10Y*
- 9.75%
QTUM
- 1D
- 1.85%
- 1M
- -6.11%
- YTD
- -0.14%
- 6M
- 3.08%
- 1Y
- 47.58%
- 3Y*
- 34.18%
- 5Y*
- 18.84%
- 10Y*
- —
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
SBIO vs. QTUM - Expense Ratio Comparison
SBIO has a 0.50% expense ratio, which is higher than QTUM's 0.40% expense ratio.
Return for Risk
SBIO vs. QTUM — Risk / Return Rank
SBIO
QTUM
SBIO vs. QTUM - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for ALPS Medical Breakthroughs ETF (SBIO) and Defiance Quantum ETF (QTUM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| SBIO | QTUM | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 2.92 | 1.61 | +1.31 |
Sortino ratioReturn per unit of downside risk | 3.57 | 2.24 | +1.33 |
Omega ratioGain probability vs. loss probability | 1.45 | 1.30 | +0.15 |
Calmar ratioReturn relative to maximum drawdown | 5.66 | 3.16 | +2.49 |
Martin ratioReturn relative to average drawdown | 19.94 | 11.08 | +8.86 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Loading graphics...
Sharpe Ratios by Period
| SBIO | QTUM | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 2.92 | 1.61 | +1.31 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.05 | 0.72 | -0.67 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.29 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.23 | 0.84 | -0.62 |
Correlation
The correlation between SBIO and QTUM is 0.57, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.
Dividends
SBIO vs. QTUM - Dividend Comparison
SBIO has not paid dividends to shareholders, while QTUM's dividend yield for the trailing twelve months is around 1.07%.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
SBIO ALPS Medical Breakthroughs ETF | 0.00% | 0.00% | 3.55% | 0.22% | 0.00% | 0.00% | 0.00% | 0.04% | 2.79% | 1.77% |
QTUM Defiance Quantum ETF | 1.07% | 1.01% | 0.61% | 0.81% | 1.46% | 0.48% | 0.42% | 0.61% | 0.21% | 0.00% |
Drawdowns
SBIO vs. QTUM - Drawdown Comparison
The maximum SBIO drawdown since its inception was -63.06%, which is greater than QTUM's maximum drawdown of -38.45%. Use the drawdown chart below to compare losses from any high point for SBIO and QTUM.
Loading graphics...
Drawdown Indicators
| SBIO | QTUM | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -63.06% | -38.45% | -24.61% |
Max Drawdown (1Y)Largest decline over 1 year | -15.08% | -15.26% | +0.18% |
Max Drawdown (5Y)Largest decline over 5 years | -53.67% | -38.45% | -15.22% |
Max Drawdown (10Y)Largest decline over 10 years | -63.06% | — | — |
Current DrawdownCurrent decline from peak | -13.79% | -9.34% | -4.45% |
Average DrawdownAverage peak-to-trough decline | -28.70% | -8.40% | -20.30% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.28% | 4.36% | -0.08% |
Volatility
SBIO vs. QTUM - Volatility Comparison
ALPS Medical Breakthroughs ETF (SBIO) has a higher volatility of 12.61% compared to Defiance Quantum ETF (QTUM) at 9.77%. This indicates that SBIO's price experiences larger fluctuations and is considered to be riskier than QTUM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading graphics...
Volatility by Period
| SBIO | QTUM | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 12.61% | 9.77% | +2.84% |
Volatility (6M)Calculated over the trailing 6-month period | 22.09% | 20.87% | +1.22% |
Volatility (1Y)Calculated over the trailing 1-year period | 33.43% | 29.70% | +3.73% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 33.55% | 26.21% | +7.34% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 33.34% | 27.05% | +6.29% |