SBIO vs. GSG
SBIO (ALPS Medical Breakthroughs ETF) and GSG (iShares S&P GSCI Commodity-Indexed Trust) are both exchange-traded funds - SBIO is a Health & Biotech Equities fund tracking the S-Network Medical Breakthroughs Index, while GSG is a Commodities fund tracking the S&P GSCI Total Return Index. Both are passively managed. Over the past 10 years, SBIO returned 11.19%/yr vs 7.61%/yr for GSG. At a 0.12 correlation, their price movements are largely independent. SBIO charges 0.50%/yr vs 0.75%/yr for GSG.
Performance
SBIO vs. GSG - Performance Comparison
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Returns By Period
In the year-to-date period, SBIO achieves a 23.86% return, which is significantly lower than GSG's 33.95% return. Over the past 10 years, SBIO has outperformed GSG with an annualized return of 11.19%, while GSG has yielded a comparatively lower 7.61% annualized return.
SBIO
- 1D
- -3.19%
- 1M
- 19.11%
- 6M
- 23.86%
- YTD
- 23.86%
- 1Y
- 91.90%
- 3Y*
- 26.50%
- 5Y*
- 7.62%
- 10Y*
- 11.19%
GSG
- 1D
- -0.93%
- 1M
- 4.15%
- 6M
- 29.74%
- YTD
- 33.95%
- 1Y
- 37.41%
- 3Y*
- 15.32%
- 5Y*
- 14.20%
- 10Y*
- 7.61%
SBIO vs. GSG - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
SBIO ALPS Medical Breakthroughs ETF | 23.86% | 55.07% | 3.81% | 8.68% | -28.08% | -17.55% | 21.17% | 50.30% | -11.81% | 45.67% |
GSG iShares S&P GSCI Commodity-Indexed Trust | 33.95% | 5.93% | 8.52% | -5.51% | 24.08% | 38.77% | -23.94% | 15.62% | -13.88% | 3.89% |
Correlation
The correlation between SBIO and GSG is -0.22, meaning they tend to move in opposite directions. This is especially valuable for risk management - when one declines, the other has historically tended to hold steady or rise.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | -0.22 |
Correlation (3Y) Calculated over the trailing 3-year period | -0.08 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.02 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.12 |
Correlation (All Time) Calculated using the full available price history since Dec 31, 2014 | 0.12 |
The correlation between SBIO and GSG shifts across timeframes, from -0.22 (1 year) to 0.12 (all time), reflecting how their relationship changes across market environments.
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Return for Risk
SBIO vs. GSG — Risk / Return Rank
SBIO
GSG
SBIO vs. GSG - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for ALPS Medical Breakthroughs ETF (SBIO) and iShares S&P GSCI Commodity-Indexed Trust (GSG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| SBIO | GSG | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.42 | ||
| Sortino ratioReturn per unit of downside risk | +1.64 | ||
| Omega ratioGain probability vs. loss probability | 1.46 | 1.29 | +0.17 |
| Calmar ratioReturn relative to maximum drawdown | 7.30 | 2.00 | +5.30 |
| Martin ratioReturn relative to average drawdown | 20.11 | 6.66 | +13.45 |
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Drawdowns
SBIO vs. GSG - Drawdown Comparison
The maximum SBIO drawdown since its inception was -63.06%, smaller than the maximum GSG drawdown of -89.62%. Use the drawdown chart below to compare losses from any high point for SBIO and GSG.
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Drawdown Indicators
| SBIO | GSG | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -63.06% | -89.62% | +26.56% |
Max Drawdown (1Y)Largest decline over 1 year | -12.66% | -18.81% | +6.15% |
Max Drawdown (3Y)Largest decline over 3 years | -42.44% | -18.81% | -23.63% |
Max Drawdown (5Y)Largest decline over 5 years | -52.49% | -29.12% | -23.37% |
Max Drawdown (10Y)Largest decline over 10 years | -63.06% | -57.64% | -5.42% |
Current DrawdownCurrent decline from peak | -7.98% | -59.56% | +51.58% |
Average DrawdownAverage peak-to-trough decline | -28.22% | -63.68% | +35.46% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.59% | 5.63% | -1.04% |
Volatility
SBIO vs. GSG - Volatility Comparison
ALPS Medical Breakthroughs ETF (SBIO) has a higher volatility of 10.80% compared to iShares S&P GSCI Commodity-Indexed Trust (GSG) at 7.17%. This indicates that SBIO's price experiences larger fluctuations and is considered to be riskier than GSG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| SBIO | GSG | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 10.80% | 7.17% | +3.63% |
Volatility (6M)Calculated over the trailing 6-month period | 24.13% | 21.54% | +2.59% |
Volatility (1Y)Calculated over the trailing 1-year period | 30.61% | 23.48% | +7.13% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 33.88% | 22.80% | +11.08% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 33.16% | 22.00% | +11.16% |
SBIO vs. GSG - Expense Ratio Comparison
SBIO has a 0.50% expense ratio, which is lower than GSG's 0.75% expense ratio.
Dividends
SBIO vs. GSG - Dividend Comparison
Neither SBIO nor GSG has paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
GSG iShares S&P GSCI Commodity-Indexed Trust | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SBIO ALPS Medical Breakthroughs ETF | 0.00% | 0.00% | 3.55% | 0.22% | 0.00% | 0.00% | 0.00% | 0.04% | 2.79% | 1.77% |
Frequently Asked Questions
SBIO and GSG have a correlation of -0.22, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SBIO has higher volatility (10.80%) compared to GSG (7.17%). In terms of maximum drawdown, SBIO dropped -63.06% vs GSG's -89.62%.
On 10-year performance, SBIO leads with 11.19% vs 7.61% for GSG. On fees, SBIO is cheaper at 0.50% per year. On volatility, GSG has been the lower-risk option at 7.17%. The better choice depends on whether you care most about return, fees, risk, or income.
Over the 10-year period, SBIO has performed better with a 11.19% return vs 7.61%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.
SBIO is cheaper with a 0.50% expense ratio, compared with 0.75% for GSG.
SBIO and GSG have nearly identical dividend yields, around 0.00%.
SBIO is categorized as Health & Biotech Equities, while GSG is Commodities. SBIO tracks S-Network Medical Breakthroughs Index, while GSG tracks S&P GSCI Total Return Index. They also come from different issuers: SS&C and iShares. Their fees differ too: 0.50% for SBIO and 0.75% for GSG.
SBIO currently has the higher Sharpe Ratio (3.02 vs 1.60), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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