REPL vs. DNN

Last updated Jun 6, 2026

REPL (Replimune Group, Inc.) and DNN (Denison Mines Corp) are both stocks. REPL operates in Biotechnology (Healthcare), while DNN operates in Uranium (Energy). Over the past 5 years, REPL returned -21.61%/yr vs 17.20%/yr for DNN. At a 0.19 correlation, their price movements are largely independent.

Performance

REPL vs. DNN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Replimune Group, Inc. (REPL) and Denison Mines Corp (DNN). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, REPL achieves a -2.57% return, which is significantly lower than DNN's 13.91% return.

REPL

• 1D: -4.05%
• 1M: 183.53%
• YTD: -2.57%
• 6M: -10.74%
• 1Y: -8.77%
• 3Y*: -26.27%
• 5Y*: -21.61%
• 10Y*: —

DNN

• 1D: -11.14%
• 1M: -18.98%
• YTD: 13.91%
• 6M: 10.58%
• 1Y: 80.36%
• 3Y*: 36.94%
• 5Y*: 17.20%
• 10Y*: 18.41%

*Multi-year figures are annualized to reflect compound growth (CAGR)

REPL vs. DNN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
REPL Replimune Group, Inc.	-2.57%	-19.74%	43.65%	-69.01%	0.37%	-28.96%	165.85%	43.50%	-34.04%
DNN Denison Mines Corp	13.91%	47.78%	1.69%	53.91%	-16.06%	111.75%	54.05%	-9.48%	-3.33%

Correlation

The correlation between REPL and DNN is 0.15, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.15
Correlation (3Y) Calculated over the trailing 3-year period	0.10
Correlation (5Y) Calculated over the trailing 5-year period	0.21
Correlation (All Time) Calculated using the full available price history since Jul 23, 2018	0.19

The correlation between REPL and DNN shifts across timeframes, from 0.10 (3 years) to 0.21 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap REPL : $873.02M DNN : $2.74B
EPS REPL : -$3.43 DNN : -$0.28
PB Ratio REPL : 4.15 DNN : 10.49
Total Revenue (TTM) REPL : $0.00 DNN : $4.34M
Gross Profit (TTM) REPL : -$2.49M DNN : -$12.87M
EBITDA (TTM) REPL : -$315.29M DNN : -$155.36M

Return for Risk

REPL vs. DNN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

REPL

REPL Risk / Return Rank: 57
REPL Sharpe Ratio Rank: 41
REPL Sortino Ratio Rank: 77
REPL Omega Ratio Rank: 88
REPL Calmar Ratio Rank: 40
REPL Martin Ratio Rank: 40

DNN

DNN Risk / Return Rank: 78
DNN Sharpe Ratio Rank: 80
DNN Sortino Ratio Rank: 76
DNN Omega Ratio Rank: 72
DNN Calmar Ratio Rank: 81
DNN Martin Ratio Rank: 81

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

REPL vs. DNN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Replimune Group, Inc. (REPL) and Denison Mines Corp (DNN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	REPL	DNN	Difference
Sharpe ratio: Return per unit of total volatility	-0.01	1.42	-1.44
Sortino ratio: Return per unit of downside risk	2.11	2.04	+0.06
Omega ratio: Gain probability vs. loss probability	1.39	1.24	+0.15
Calmar ratio: Return relative to maximum drawdown	-0.03	2.85	-2.89
Martin ratio: Return relative to average drawdown	-0.06	6.71	-6.77
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

REPL vs. DNN - Sharpe Ratio Comparison

The current REPL Sharpe Ratio is -0.01, which is lower than the DNN Sharpe Ratio of 1.42. The chart below compares the historical Sharpe Ratios of REPL and DNN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	REPL	DNN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.01	1.42	-1.44
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.18	0.27	-0.45
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.29	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.05	-0.08	+0.03

Drawdowns

REPL vs. DNN - Drawdown Comparison

The maximum REPL drawdown since its inception was -96.77%, roughly equal to the maximum DNN drawdown of -98.96%. Use the drawdown chart below to compare losses from any high point for REPL and DNN.

Drawdown Indicators

	REPL	DNN	Difference
Max Drawdown Largest peak-to-trough decline	-96.77%	-98.96%	+2.19%
Max Drawdown (1Y) Largest decline over 1 year	-86.54%	-30.66%	-55.88%
Max Drawdown (3Y) Largest decline over 3 years	-92.95%	-52.48%	-40.47%
Max Drawdown (5Y) Largest decline over 5 years	-95.70%	-55.66%	-40.04%
Max Drawdown (10Y) Largest decline over 10 years	—	-75.90%	—
Current Drawdown Current decline from peak	-82.01%	-84.29%	+2.28%
Average Drawdown Average peak-to-trough decline	-55.55%	-85.07%	+29.52%
Ulcer Index Depth and duration of drawdowns from previous peaks	47.15%	13.01%	+34.14%

Volatility

REPL vs. DNN - Volatility Comparison

Replimune Group, Inc. (REPL) has a higher volatility of 72.83% compared to Denison Mines Corp (DNN) at 18.58%. This indicates that REPL's price experiences larger fluctuations and is considered to be riskier than DNN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	REPL	DNN	Difference
Volatility (1M) Calculated over the trailing 1-month period	72.83%	18.58%	+54.25%
Volatility (6M) Calculated over the trailing 6-month period	148.44%	46.42%	+102.02%
Volatility (1Y) Calculated over the trailing 1-year period	226.75%	61.50%	+165.25%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	119.74%	63.54%	+56.20%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	108.24%	64.27%	+43.97%

Dividends

REPL vs. DNN - Dividend Comparison

Neither REPL nor DNN has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both REPL and DNN in my portfolio?

REPL and DNN have a correlation of 0.15, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, REPL or DNN?

REPL has higher volatility (72.83%) compared to DNN (18.58%). In terms of maximum drawdown, REPL dropped -96.77% vs DNN's -98.96%.

Which has better risk-adjusted returns?

DNN currently has the higher Sharpe Ratio (1.42 vs -0.01), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.