REPL vs. COIN

Last updated Jun 6, 2026

REPL (Replimune Group, Inc.) and COIN (Coinbase Global, Inc.) are both stocks. REPL operates in Biotechnology (Healthcare), while COIN operates in Financial Data & Stock Exchanges (Financial Services). Over the past 5 years, REPL returned -21.61%/yr vs -7.80%/yr for COIN. At a 0.22 correlation, their price movements are largely independent.

Performance

REPL vs. COIN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Replimune Group, Inc. (REPL) and Coinbase Global, Inc. (COIN). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, REPL achieves a -2.57% return, which is significantly higher than COIN's -32.61% return.

REPL

• 1D: -4.05%
• 1M: 183.53%
• YTD: -2.57%
• 6M: -10.74%
• 1Y: -8.77%
• 3Y*: -26.27%
• 5Y*: -21.61%
• 10Y*: —

COIN

• 1D: -7.15%
• 1M: -21.02%
• YTD: -32.61%
• 6M: -43.50%
• 1Y: -39.35%
• 3Y*: 43.47%
• 5Y*: -7.80%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

REPL vs. COIN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
REPL Replimune Group, Inc.	-2.57%	-19.74%	43.65%	-69.01%	0.37%	-11.15%
COIN Coinbase Global, Inc.	-32.61%	-8.92%	42.77%	391.44%	-85.98%	-23.12%

Correlation

The correlation between REPL and COIN is 0.06, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.06
Correlation (3Y) Calculated over the trailing 3-year period	0.13
Correlation (5Y) Calculated over the trailing 5-year period	0.22
Correlation (All Time) Calculated using the full available price history since Apr 15, 2021	0.22

The correlation between REPL and COIN shifts across timeframes, from 0.06 (1 year) to 0.22 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap REPL : $873.02M COIN : $40.35B
EPS REPL : -$3.43 COIN : $2.90
PB Ratio REPL : 4.15 COIN : 2.99
Total Revenue (TTM) REPL : $0.00 COIN : $5.81B
Gross Profit (TTM) REPL : -$2.49M COIN : $4.65B
EBITDA (TTM) REPL : -$315.29M COIN : $1.68B

Return for Risk

REPL vs. COIN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

REPL

REPL Risk / Return Rank: 57
REPL Sharpe Ratio Rank: 41
REPL Sortino Ratio Rank: 77
REPL Omega Ratio Rank: 88
REPL Calmar Ratio Rank: 40
REPL Martin Ratio Rank: 40

COIN

COIN Risk / Return Rank: 21
COIN Sharpe Ratio Rank: 18
COIN Sortino Ratio Rank: 20
COIN Omega Ratio Rank: 21
COIN Calmar Ratio Rank: 21
COIN Martin Ratio Rank: 23

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

REPL vs. COIN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Replimune Group, Inc. (REPL) and Coinbase Global, Inc. (COIN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	REPL	COIN	Difference
Sharpe ratio: Return per unit of total volatility	-0.01	-0.54	+0.52
Sortino ratio: Return per unit of downside risk	2.11	-0.48	+2.59
Omega ratio: Gain probability vs. loss probability	1.39	0.95	+0.44
Calmar ratio: Return relative to maximum drawdown	-0.03	-0.57	+0.53
Martin ratio: Return relative to average drawdown	-0.06	-0.94	+0.88
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

REPL vs. COIN - Sharpe Ratio Comparison

The current REPL Sharpe Ratio is -0.01, which is higher than the COIN Sharpe Ratio of -0.54. The chart below compares the historical Sharpe Ratios of REPL and COIN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	REPL	COIN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.01	-0.54	+0.52
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.18	-0.09	-0.09
Sharpe Ratio (All Time) Calculated using the full available price history	-0.05	-0.16	+0.11

Drawdowns

REPL vs. COIN - Drawdown Comparison

The maximum REPL drawdown since its inception was -96.77%, which is greater than COIN's maximum drawdown of -90.90%. Use the drawdown chart below to compare losses from any high point for REPL and COIN.

Drawdown Indicators

	REPL	COIN	Difference
Max Drawdown Largest peak-to-trough decline	-96.77%	-90.90%	-5.87%
Max Drawdown (1Y) Largest decline over 1 year	-86.54%	-66.39%	-20.15%
Max Drawdown (3Y) Largest decline over 3 years	-92.95%	-66.39%	-26.56%
Max Drawdown (5Y) Largest decline over 5 years	-95.70%	-90.90%	-4.80%
Current Drawdown Current decline from peak	-82.01%	-63.70%	-18.31%
Average Drawdown Average peak-to-trough decline	-55.55%	-49.85%	-5.70%
Ulcer Index Depth and duration of drawdowns from previous peaks	47.15%	40.06%	+7.09%

Volatility

REPL vs. COIN - Volatility Comparison

Replimune Group, Inc. (REPL) has a higher volatility of 72.83% compared to Coinbase Global, Inc. (COIN) at 20.16%. This indicates that REPL's price experiences larger fluctuations and is considered to be riskier than COIN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	REPL	COIN	Difference
Volatility (1M) Calculated over the trailing 1-month period	72.83%	20.16%	+52.67%
Volatility (6M) Calculated over the trailing 6-month period	148.44%	51.15%	+97.29%
Volatility (1Y) Calculated over the trailing 1-year period	226.75%	70.37%	+156.38%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	119.74%	85.87%	+33.87%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	108.24%	85.38%	+22.86%

Dividends

REPL vs. COIN - Dividend Comparison

Neither REPL nor COIN has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both REPL and COIN in my portfolio?

REPL and COIN have a correlation of 0.06, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, REPL or COIN?

REPL has higher volatility (72.83%) compared to COIN (20.16%). In terms of maximum drawdown, REPL dropped -96.77% vs COIN's -90.90%.

Which has better risk-adjusted returns?

REPL currently has the higher Sharpe Ratio (-0.01 vs -0.54), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.