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QURE vs. MPWR
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

QURE vs. MPWR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in uniQure N.V. (QURE) and Monolithic Power Systems, Inc. (MPWR). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, QURE achieves a 15.21% return, which is significantly lower than MPWR's 74.38% return. Over the past 10 years, QURE has underperformed MPWR with an annualized return of 11.46%, while MPWR has yielded a comparatively higher 37.94% annualized return.


QURE

1D
2.80%
1M
-5.49%
YTD
15.21%
6M
41.31%
1Y
72.42%
3Y*
10.96%
5Y*
-5.23%
10Y*
11.46%

MPWR

1D
-0.77%
1M
-4.43%
YTD
74.38%
6M
67.26%
1Y
121.18%
3Y*
44.43%
5Y*
36.35%
10Y*
37.94%
*Multi-year figures are annualized to reflect compound growth (CAGR)

QURE vs. MPWR - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
QURE
uniQure N.V.
15.21%35.50%160.86%-70.14%9.31%-42.60%-49.58%148.65%47.12%249.82%
MPWR
Monolithic Power Systems, Inc.
74.38%54.45%-5.55%79.78%-27.78%35.49%107.49%54.80%4.49%38.23%

Correlation

The correlation between QURE and MPWR is 0.07, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.07

Correlation (3Y)
Calculated over the trailing 3-year period

0.15

Correlation (5Y)
Calculated over the trailing 5-year period

0.26

Correlation (10Y)
Calculated over the trailing 10-year period

0.27

Correlation (All Time)
Calculated using the full available price history since Feb 5, 2014

0.26

The correlation between QURE and MPWR shifts across timeframes, from 0.07 (1 year) to 0.27 (10 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

QURE:

$1.73B

MPWR:

$77.67B

EPS

QURE:

-$3.58

MPWR:

$13.89

PS Ratio

QURE:

88.98

MPWR:

25.93

PB Ratio

QURE:

11.58

MPWR:

21.12

Total Revenue (TTM)

QURE:

$18.09M

MPWR:

$2.96B

Gross Profit (TTM)

QURE:

$13.42M

MPWR:

$1.63B

EBITDA (TTM)

QURE:

-$164.53M

MPWR:

$861.78M

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Return for Risk

QURE vs. MPWR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

QURE
QURE Risk / Return Rank: 7070
Overall Rank
QURE Sharpe Ratio Rank: 5353
Sharpe Ratio Rank
QURE Sortino Ratio Rank: 8989
Sortino Ratio Rank
QURE Omega Ratio Rank: 9292
Omega Ratio Rank
QURE Calmar Ratio Rank: 6161
Calmar Ratio Rank
QURE Martin Ratio Rank: 5757
Martin Ratio Rank

MPWR
MPWR Risk / Return Rank: 9191
Overall Rank
MPWR Sharpe Ratio Rank: 9393
Sharpe Ratio Rank
MPWR Sortino Ratio Rank: 9090
Sortino Ratio Rank
MPWR Omega Ratio Rank: 8888
Omega Ratio Rank
MPWR Calmar Ratio Rank: 9393
Calmar Ratio Rank
MPWR Martin Ratio Rank: 9393
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

QURE vs. MPWR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for uniQure N.V. (QURE) and Monolithic Power Systems, Inc. (MPWR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


QUREMPWRDifference
Sharpe ratioReturn per unit of total volatility

-2.25

Sortino ratioReturn per unit of downside risk

-0.01

Omega ratioGain probability vs. loss probability

1.45

1.37

+0.08

Calmar ratioReturn relative to maximum drawdown

0.83

5.43

-4.59

Martin ratioReturn relative to average drawdown

1.35

14.45

-13.10

QURE vs. MPWR - Sharpe Ratio Comparison

The current QURE Sharpe Ratio is 0.27, which is lower than the MPWR Sharpe Ratio of 2.51. The chart below compares the historical Sharpe Ratios of QURE and MPWR, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

QURE vs. MPWR - Drawdown Comparison

The maximum QURE drawdown since its inception was -95.40%, which is greater than MPWR's maximum drawdown of -72.27%. Use the drawdown chart below to compare losses from any high point for QURE and MPWR.


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Drawdown Indicators


QUREMPWRDifference

Max Drawdown

Largest peak-to-trough decline

-95.40%

-72.27%

-23.13%

Max Drawdown (1Y)

Largest decline over 1 year

-87.21%

-22.45%

-64.76%

Max Drawdown (3Y)

Largest decline over 3 years

-87.21%

-51.65%

-35.56%

Max Drawdown (5Y)

Largest decline over 5 years

-90.11%

-51.65%

-38.46%

Max Drawdown (10Y)

Largest decline over 10 years

-95.40%

-51.65%

-43.75%

Current Drawdown

Current decline from peak

-66.46%

-6.66%

-59.80%

Average Drawdown

Average peak-to-trough decline

-56.61%

-17.71%

-38.90%

Ulcer Index

Depth and duration of drawdowns from previous peaks

53.75%

8.44%

+45.31%

Volatility

QURE vs. MPWR - Volatility Comparison

uniQure N.V. (QURE) has a higher volatility of 24.13% compared to Monolithic Power Systems, Inc. (MPWR) at 20.33%. This indicates that QURE's price experiences larger fluctuations and is considered to be riskier than MPWR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


QUREMPWRDifference

Volatility (1M)

Calculated over the trailing 1-month period

24.13%

20.33%

+3.80%

Volatility (6M)

Calculated over the trailing 6-month period

92.07%

37.42%

+54.65%

Volatility (1Y)

Calculated over the trailing 1-year period

273.03%

48.53%

+224.50%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

154.02%

53.53%

+100.49%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

119.76%

47.23%

+72.53%

Dividends

QURE vs. MPWR - Dividend Comparison

QURE has not paid dividends to shareholders, while MPWR's dividend yield for the trailing twelve months is around 0.42%.


PositionTTM20252024202320222021202020192018201720162015
MPWR
Monolithic Power Systems, Inc.
0.42%0.69%0.85%0.63%0.85%0.49%0.55%0.90%1.03%0.71%0.98%1.26%
QURE
uniQure N.V.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

Financials

QURE vs. MPWR - Financials Comparison

This section allows you to compare key financial metrics between uniQure N.V. and Monolithic Power Systems, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00200.00M400.00M600.00M800.00M20222023202420252026
3.56M
804.19M
(QURE) Total Revenue
(MPWR) Total Revenue
Values in USD except per share items

Frequently Asked Questions


QURE and MPWR have a correlation of 0.07, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

QURE has higher volatility (24.13%) compared to MPWR (20.33%). In terms of maximum drawdown, QURE dropped -95.40% vs MPWR's -72.27%.

MPWR currently has the higher Sharpe Ratio (2.51 vs 0.27), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for QURE and MPWR

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

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