QURE vs. ESPR
QURE (uniQure N.V.) and ESPR (Esperion Therapeutics, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, QURE returned 11.46%/yr vs -14.95%/yr for ESPR. At a 0.32 correlation, their price movements are largely independent.
Performance
QURE vs. ESPR - Performance Comparison
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Returns By Period
In the year-to-date period, QURE achieves a 15.21% return, which is significantly higher than ESPR's -14.86% return. Over the past 10 years, QURE has outperformed ESPR with an annualized return of 11.46%, while ESPR has yielded a comparatively lower -14.95% annualized return.
QURE
- 1D
- 2.80%
- 1M
- -5.49%
- YTD
- 15.21%
- 6M
- 41.31%
- 1Y
- 72.42%
- 3Y*
- 10.96%
- 5Y*
- -5.23%
- 10Y*
- 11.46%
ESPR
- 1D
- 0.00%
- 1M
- 0.96%
- YTD
- -14.86%
- 6M
- -18.18%
- 1Y
- 162.50%
- 3Y*
- 35.36%
- 5Y*
- -34.62%
- 10Y*
- -14.95%
QURE vs. ESPR - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
QURE uniQure N.V. | 15.21% | 35.50% | 160.86% | -70.14% | 9.31% | -42.60% | -49.58% | 148.65% | 47.12% | 249.82% |
ESPR Esperion Therapeutics, Inc. | -14.86% | 68.18% | -26.42% | -52.01% | 24.60% | -80.77% | -56.40% | 29.63% | -30.13% | 425.88% |
Correlation
The correlation between QURE and ESPR is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.24 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.28 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.31 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.32 |
Correlation (All Time) Calculated using the full available price history since Feb 5, 2014 | 0.32 |
Fundamentals
QURE:
$1.73B
ESPR:
$791.76M
QURE:
-$3.58
ESPR:
-$0.03
QURE:
88.98
ESPR:
1.75
QURE:
$18.09M
ESPR:
$418.24M
QURE:
$13.42M
ESPR:
$226.32M
QURE:
-$164.53M
ESPR:
$77.18M
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Return for Risk
QURE vs. ESPR — Risk / Return Rank
QURE
ESPR
QURE vs. ESPR - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for uniQure N.V. (QURE) and Esperion Therapeutics, Inc. (ESPR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| QURE | ESPR | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.50 | ||
| Sortino ratioReturn per unit of downside risk | +0.13 | ||
| Omega ratioGain probability vs. loss probability | 1.45 | 1.36 | +0.09 |
| Calmar ratioReturn relative to maximum drawdown | 0.83 | 3.07 | -2.24 |
| Martin ratioReturn relative to average drawdown | 1.35 | 7.68 | -6.33 |
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Drawdowns
QURE vs. ESPR - Drawdown Comparison
The maximum QURE drawdown since its inception was -95.40%, roughly equal to the maximum ESPR drawdown of -99.37%. Use the drawdown chart below to compare losses from any high point for QURE and ESPR.
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Drawdown Indicators
| QURE | ESPR | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -95.40% | -99.37% | +3.97% |
Max Drawdown (1Y)Largest decline over 1 year | -87.21% | -53.19% | -34.02% |
Max Drawdown (3Y)Largest decline over 3 years | -87.21% | -80.94% | -6.27% |
Max Drawdown (5Y)Largest decline over 5 years | -90.11% | -97.16% | +7.05% |
Max Drawdown (10Y)Largest decline over 10 years | -95.40% | -99.10% | +3.70% |
Current DrawdownCurrent decline from peak | -66.46% | -97.27% | +30.81% |
Average DrawdownAverage peak-to-trough decline | -56.61% | -69.99% | +13.38% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 53.75% | 21.30% | +32.45% |
Volatility
QURE vs. ESPR - Volatility Comparison
uniQure N.V. (QURE) has a higher volatility of 24.13% compared to Esperion Therapeutics, Inc. (ESPR) at 1.06%. This indicates that QURE's price experiences larger fluctuations and is considered to be riskier than ESPR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| QURE | ESPR | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 24.13% | 1.06% | +23.07% |
Volatility (6M)Calculated over the trailing 6-month period | 92.07% | 61.44% | +30.63% |
Volatility (1Y)Calculated over the trailing 1-year period | 273.03% | 92.66% | +180.37% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 154.02% | 91.79% | +62.23% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 119.76% | 84.61% | +35.15% |
Dividends
QURE vs. ESPR - Dividend Comparison
Neither QURE nor ESPR has paid dividends to shareholders.
Financials
QURE vs. ESPR - Financials Comparison
This section allows you to compare key financial metrics between uniQure N.V. and Esperion Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
QURE and ESPR have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
QURE has higher volatility (24.13%) compared to ESPR (1.06%). In terms of maximum drawdown, QURE dropped -95.40% vs ESPR's -99.37%.
ESPR currently has the higher Sharpe Ratio (1.76 vs 0.27), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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