PRME vs. TNGX
PRME (Prime Medicine Inc. Common Stock) and TNGX (Tango Therapeutics, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 3 years, PRME returned -40.00%/yr vs 96.53%/yr for TNGX. At a 0.28 correlation, their price movements are largely independent.
Performance
PRME vs. TNGX - Performance Comparison
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Returns By Period
In the year-to-date period, PRME achieves a -6.63% return, which is significantly lower than TNGX's 220.43% return.
PRME
- 1D
- -3.86%
- 1M
- 9.09%
- YTD
- -6.63%
- 6M
- -12.20%
- 1Y
- 50.00%
- 3Y*
- -40.00%
- 5Y*
- —
- 10Y*
- —
TNGX
- 1D
- -0.39%
- 1M
- 40.27%
- YTD
- 220.43%
- 6M
- 232.83%
- 1Y
- 433.65%
- 3Y*
- 96.53%
- 5Y*
- 20.02%
- 10Y*
- —
PRME vs. TNGX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
PRME Prime Medicine Inc. Common Stock | -6.63% | 18.84% | -67.04% | -52.31% | -2.06% |
TNGX Tango Therapeutics, Inc. | 220.43% | 186.73% | -68.79% | 36.55% | 3.87% |
Correlation
The correlation between PRME and TNGX is 0.27, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.27 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.29 |
Correlation (All Time) Calculated using the full available price history since Oct 20, 2022 | 0.28 |
Fundamentals
PRME:
$573.79M
TNGX:
$4.08B
PRME:
-$1.29
TNGX:
-$0.89
PRME:
156.89
TNGX:
59.93
PRME:
7.48
TNGX:
10.41
PRME:
$3.18M
TNGX:
$56.99M
PRME:
-$4.14M
TNGX:
$55.33M
PRME:
-$195.72M
TNGX:
-$111.92M
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Return for Risk
PRME vs. TNGX — Risk / Return Rank
PRME
TNGX
PRME vs. TNGX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Prime Medicine Inc. Common Stock (PRME) and Tango Therapeutics, Inc. (TNGX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| PRME | TNGX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -3.83 | ||
| Sortino ratioReturn per unit of downside risk | -2.97 | ||
| Omega ratioGain probability vs. loss probability | 1.15 | 1.55 | -0.40 |
| Calmar ratioReturn relative to maximum drawdown | 0.84 | 14.95 | -14.11 |
| Martin ratioReturn relative to average drawdown | 1.31 | 38.53 | -37.22 |
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Drawdowns
PRME vs. TNGX - Drawdown Comparison
The maximum PRME drawdown since its inception was -94.55%, roughly equal to the maximum TNGX drawdown of -93.64%. Use the drawdown chart below to compare losses from any high point for PRME and TNGX.
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Drawdown Indicators
| PRME | TNGX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -94.55% | -93.64% | -0.91% |
Max Drawdown (1Y)Largest decline over 1 year | -59.52% | -29.24% | -30.28% |
Max Drawdown (3Y)Largest decline over 3 years | -92.37% | -91.46% | -0.91% |
Max Drawdown (5Y)Largest decline over 5 years | — | -93.64% | — |
Current DrawdownCurrent decline from peak | -84.66% | -13.71% | -70.95% |
Average DrawdownAverage peak-to-trough decline | -65.64% | -47.81% | -17.83% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 38.15% | 11.32% | +26.83% |
Volatility
PRME vs. TNGX - Volatility Comparison
The current volatility for Prime Medicine Inc. Common Stock (PRME) is 26.62%, while Tango Therapeutics, Inc. (TNGX) has a volatility of 50.81%. This indicates that PRME experiences smaller price fluctuations and is considered to be less risky than TNGX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| PRME | TNGX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 26.62% | 50.81% | -24.19% |
Volatility (6M)Calculated over the trailing 6-month period | 53.91% | 79.15% | -25.24% |
Volatility (1Y)Calculated over the trailing 1-year period | 95.98% | 100.42% | -4.44% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 90.35% | 102.22% | -11.87% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 90.35% | 96.03% | -5.68% |
Dividends
PRME vs. TNGX - Dividend Comparison
Neither PRME nor TNGX has paid dividends to shareholders.
Financials
PRME vs. TNGX - Financials Comparison
This section allows you to compare key financial metrics between Prime Medicine Inc. Common Stock and Tango Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
PRME and TNGX have a correlation of 0.27, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TNGX has higher volatility (50.81%) compared to PRME (26.62%). In terms of maximum drawdown, PRME dropped -94.55% vs TNGX's -93.64%.
TNGX currently has the higher Sharpe Ratio (4.36 vs 0.52), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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