PRME vs. HIMS

Last updated Jun 4, 2026

PRME (Prime Medicine Inc. Common Stock) and HIMS (Hims & Hers Health, Inc.) are both stocks. PRME operates in Biotechnology (Healthcare), while HIMS operates in Household & Personal Products (Consumer Defensive). Over the past 3 years, PRME returned -42.02%/yr vs 45.13%/yr for HIMS. At a 0.31 correlation, their price movements are largely independent.

Performance

PRME vs. HIMS - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Prime Medicine Inc. Common Stock (PRME) and Hims & Hers Health, Inc. (HIMS). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PRME achieves a -9.51% return, which is significantly higher than HIMS's -15.28% return.

PRME

• 1D: -2.18%
• 1M: -9.51%
• YTD: -9.51%
• 6M: -13.02%
• 1Y: 136.09%
• 3Y*: -42.02%
• 5Y*: —
• 10Y*: —

HIMS

• 1D: 0.00%
• 1M: 0.88%
• YTD: -15.28%
• 6M: -25.79%
• 1Y: -49.74%
• 3Y*: 45.13%
• 5Y*: 14.51%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

PRME vs. HIMS - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022
PRME Prime Medicine Inc. Common Stock	-9.51%	18.84%	-67.04%	-52.31%	20.88%
HIMS Hims & Hers Health, Inc.	-15.28%	34.28%	171.69%	38.85%	49.77%

Correlation

The correlation between PRME and HIMS is 0.37, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.37
Correlation (3Y) Calculated over the trailing 3-year period	0.34
Correlation (All Time) Calculated using the full available price history since Oct 21, 2022	0.31

Fundamentals

Market Cap PRME : $556.08M HIMS : $6.28B
EPS PRME : -$1.29 HIMS : -$0.05
PS Ratio PRME : 152.05 HIMS : 2.85
PB Ratio PRME : 7.25 HIMS : 14.08
Total Revenue (TTM) PRME : $3.18M HIMS : $2.37B
Gross Profit (TTM) PRME : -$4.14M HIMS : $1.70B
EBITDA (TTM) PRME : -$195.72M HIMS : $16.04M

Return for Risk

PRME vs. HIMS — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PRME

PRME Risk / Return Rank: 76
PRME Sharpe Ratio Rank: 79
PRME Sortino Ratio Rank: 81
PRME Omega Ratio Rank: 73
PRME Calmar Ratio Rank: 77
PRME Martin Ratio Rank: 70

HIMS

HIMS Risk / Return Rank: 20
HIMS Sharpe Ratio Rank: 18
HIMS Sortino Ratio Rank: 22
HIMS Omega Ratio Rank: 22
HIMS Calmar Ratio Rank: 17
HIMS Martin Ratio Rank: 19

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PRME vs. HIMS - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Prime Medicine Inc. Common Stock (PRME) and Hims & Hers Health, Inc. (HIMS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	PRME	HIMS	Difference
Sharpe ratio: Return per unit of total volatility	1.38	-0.52	+1.90
Sortino ratio: Return per unit of downside risk	2.39	-0.35	+2.74
Omega ratio: Gain probability vs. loss probability	1.25	0.96	+0.29
Calmar ratio: Return relative to maximum drawdown	2.30	-0.64	+2.94
Martin ratio: Return relative to average drawdown	3.78	-1.06	+4.84
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

PRME vs. HIMS - Sharpe Ratio Comparison

The current PRME Sharpe Ratio is 1.38, which is higher than the HIMS Sharpe Ratio of -0.52. The chart below compares the historical Sharpe Ratios of PRME and HIMS, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	PRME	HIMS	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.38	-0.52	+1.90
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.18	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.40	0.22	-0.61

Drawdowns

PRME vs. HIMS - Drawdown Comparison

The maximum PRME drawdown since its inception was -94.55%, which is greater than HIMS's maximum drawdown of -87.29%. Use the drawdown chart below to compare losses from any high point for PRME and HIMS.

Drawdown Indicators

	PRME	HIMS	Difference
Max Drawdown Largest peak-to-trough decline	-94.55%	-87.29%	-7.26%
Max Drawdown (1Y) Largest decline over 1 year	-59.52%	-78.06%	+18.54%
Max Drawdown (3Y) Largest decline over 3 years	-93.26%	-78.88%	-14.38%
Max Drawdown (5Y) Largest decline over 5 years	—	-79.74%	—
Current Drawdown Current decline from peak	-85.13%	-59.98%	-25.15%
Average Drawdown Average peak-to-trough decline	-65.32%	-43.19%	-22.13%
Ulcer Index Depth and duration of drawdowns from previous peaks	36.12%	47.08%	-10.96%

Volatility

PRME vs. HIMS - Volatility Comparison

The current volatility for Prime Medicine Inc. Common Stock (PRME) is 21.20%, while Hims & Hers Health, Inc. (HIMS) has a volatility of 25.84%. This indicates that PRME experiences smaller price fluctuations and is considered to be less risky than HIMS based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PRME	HIMS	Difference
Volatility (1M) Calculated over the trailing 1-month period	21.20%	25.84%	-4.64%
Volatility (6M) Calculated over the trailing 6-month period	52.94%	66.58%	-13.64%
Volatility (1Y) Calculated over the trailing 1-year period	99.57%	95.97%	+3.60%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	89.75%	83.37%	+6.38%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	89.75%	77.20%	+12.55%

Dividends

PRME vs. HIMS - Dividend Comparison

Neither PRME nor HIMS has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both PRME and HIMS in my portfolio?

PRME and HIMS have a correlation of 0.37, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PRME or HIMS?

HIMS has higher volatility (25.84%) compared to PRME (21.20%). In terms of maximum drawdown, PRME dropped -94.55% vs HIMS's -87.29%.

Which has better risk-adjusted returns?

PRME currently has the higher Sharpe Ratio (1.38 vs -0.52), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.