PHSZX vs. JFNAX

Last updated Jul 14, 2026

PHSZX (PGIM Jennison Health Sciences Fund) and JFNAX (Janus Henderson Global Life Sciences Fund Class A) are both Health & Biotech Equities funds. Over the past 10 years, PHSZX returned 13.88%/yr vs 11.60%/yr for JFNAX. Their correlation of 0.93 suggests significant overlap in exposure. PHSZX charges 0.86%/yr vs 0.98%/yr for JFNAX.

Performance

PHSZX vs. JFNAX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in PGIM Jennison Health Sciences Fund (PHSZX) and Janus Henderson Global Life Sciences Fund Class A (JFNAX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

The year-to-date returns for both stocks are quite close, with PHSZX having a 9.85% return and JFNAX slightly lower at 9.84%. Over the past 10 years, PHSZX has outperformed JFNAX with an annualized return of 13.88%, while JFNAX has yielded a comparatively lower 11.60% annualized return.

PHSZX

• 1D: -1.53%
• 1M: 11.10%
• 6M: 8.67%
• YTD: 9.85%
• 1Y: 36.67%
• 3Y*: 20.39%
• 5Y*: 9.55%
• 10Y*: 13.88%

JFNAX

• 1D: -1.57%
• 1M: 8.14%
• 6M: 8.21%
• YTD: 9.84%
• 1Y: 39.56%
• 3Y*: 14.54%
• 5Y*: 8.39%
• 10Y*: 11.60%

*Multi-year figures are annualized to reflect compound growth (CAGR)

PHSZX vs. JFNAX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
PHSZX PGIM Jennison Health Sciences Fund	9.85%	19.73%	23.04%	12.50%	-10.06%	6.09%	41.72%	18.62%	-3.77%	31.41%
JFNAX Janus Henderson Global Life Sciences Fund Class A	9.84%	24.61%	3.41%	7.35%	-2.86%	6.59%	25.42%	28.98%	4.00%	22.35%

Correlation

The correlation between PHSZX and JFNAX is 0.92, indicating a strong positive relationship between their price movements. Combining them offers limited diversification - they tend to fall together during downturns.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.92
Correlation (3Y) Calculated over the trailing 3-year period	0.90
Correlation (5Y) Calculated over the trailing 5-year period	0.93
Correlation (10Y) Calculated over the trailing 10-year period	0.92
Correlation (All Time) Calculated using the full available price history since Jul 6, 2009	0.93

The correlation between PHSZX and JFNAX has been stable across timeframes, ranging from 0.90 to 0.93 - a consistent structural relationship.

Return for Risk

PHSZX vs. JFNAX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PHSZX

PHSZX Risk / Return Rank: 67
PHSZX Sharpe Ratio Rank: 73
PHSZX Sortino Ratio Rank: 73
PHSZX Omega Ratio Rank: 58
PHSZX Calmar Ratio Rank: 79
PHSZX Martin Ratio Rank: 52

JFNAX

JFNAX Risk / Return Rank: 88
JFNAX Sharpe Ratio Rank: 90
JFNAX Sortino Ratio Rank: 88
JFNAX Omega Ratio Rank: 82
JFNAX Calmar Ratio Rank: 92
JFNAX Martin Ratio Rank: 87

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PHSZX vs. JFNAX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for PGIM Jennison Health Sciences Fund (PHSZX) and Janus Henderson Global Life Sciences Fund Class A (JFNAX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	PHSZX	JFNAX	Difference
Sharpe ratio: Return per unit of total volatility	1.89	2.44	-0.55
Sortino ratio: Return per unit of downside risk	2.71	3.53	-0.82
Omega ratio: Gain probability vs. loss probability	1.31	1.42	-0.11
Calmar ratio: Return relative to maximum drawdown	2.88	3.97	-1.08
Martin ratio: Return relative to average drawdown	8.43	12.58	-4.14

PHSZX vs. JFNAX - Sharpe Ratio Comparison

The current PHSZX Sharpe Ratio is 1.89, which is comparable to the JFNAX Sharpe Ratio of 2.44. The chart below compares the historical Sharpe Ratios of PHSZX and JFNAX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

PHSZX vs. JFNAX - Drawdown Comparison

The maximum PHSZX drawdown since its inception was -42.77%, which is greater than JFNAX's maximum drawdown of -31.07%. Use the drawdown chart below to compare losses from any high point for PHSZX and JFNAX.

Drawdown Indicators

	PHSZX	JFNAX	Difference
Max Drawdown Largest peak-to-trough decline	-42.77%	-31.07%	-11.70%
Max Drawdown (1Y) Largest decline over 1 year	-12.24%	-9.71%	-2.53%
Max Drawdown (3Y) Largest decline over 3 years	-22.06%	-21.28%	-0.78%
Max Drawdown (5Y) Largest decline over 5 years	-29.36%	-22.29%	-7.07%
Max Drawdown (10Y) Largest decline over 10 years	-30.92%	-27.39%	-3.53%
Current Drawdown Current decline from peak	-1.70%	-2.13%	+0.43%
Average Drawdown Average peak-to-trough decline	-9.90%	-6.26%	-3.64%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.19%	3.06%	+1.13%

Volatility

PHSZX vs. JFNAX - Volatility Comparison

PGIM Jennison Health Sciences Fund (PHSZX) has a higher volatility of 6.25% compared to Janus Henderson Global Life Sciences Fund Class A (JFNAX) at 5.75%. This indicates that PHSZX's price experiences larger fluctuations and is considered to be riskier than JFNAX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PHSZX	JFNAX	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.25%	5.75%	+0.50%
Volatility (6M) Calculated over the trailing 6-month period	14.78%	12.10%	+2.68%
Volatility (1Y) Calculated over the trailing 1-year period	18.71%	15.82%	+2.89%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	22.03%	16.08%	+5.95%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	23.11%	17.35%	+5.76%

PHSZX vs. JFNAX - Expense Ratio Comparison

PHSZX has a 0.86% expense ratio, which is lower than JFNAX's 0.98% expense ratio.

Dividends

PHSZX vs. JFNAX - Dividend Comparison

PHSZX's dividend yield for the trailing twelve months is around 9.95%, more than JFNAX's 4.15% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
JFNAX Janus Henderson Global Life Sciences Fund Class A	4.15%	4.56%	5.74%	4.28%	0.08%	9.90%	7.82%	6.18%	13.55%	1.03%	0.97%	8.93%
PHSZX PGIM Jennison Health Sciences Fund	9.95%	10.93%	23.93%	4.26%	1.48%	29.82%	20.26%	2.92%	11.21%	4.43%	3.44%	13.45%

Frequently Asked Questions

Can I hold both PHSZX and JFNAX in my portfolio?

With a correlation of 0.92, PHSZX and JFNAX move almost identically. Holding both adds very little diversification - you're essentially doubling your position in the same market segment. Choosing one is usually more capital-efficient.

Which is riskier, PHSZX or JFNAX?

PHSZX has higher volatility (6.25%) compared to JFNAX (5.75%). In terms of maximum drawdown, PHSZX dropped -42.77% vs JFNAX's -31.07%.

Which has better risk-adjusted returns?

JFNAX currently has the higher Sharpe Ratio (2.44 vs 1.89), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.