OPRX vs. NBIS

Last updated Jun 4, 2026

OPRX (OptimizeRx Corporation) and NBIS (Nebius Group N.V.) are both stocks. OPRX operates in Health Information Services (Healthcare), while NBIS operates in Internet Content & Information (Communication Services). Over the past year, OPRX returned -62.56% vs 575.29% for NBIS. At a 0.23 correlation, their price movements are largely independent.

Performance

OPRX vs. NBIS - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in OptimizeRx Corporation (OPRX) and Nebius Group N.V. (NBIS). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, OPRX achieves a -59.62% return, which is significantly lower than NBIS's 200.67% return.

OPRX

• 1D: -6.25%
• 1M: -26.88%
• YTD: -59.62%
• 6M: -65.43%
• 1Y: -62.56%
• 3Y*: -30.27%
• 5Y*: -37.33%
• 10Y*: 16.13%

NBIS

• 1D: -3.42%
• 1M: 42.66%
• YTD: 200.67%
• 6M: 154.43%
• 1Y: 575.29%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

OPRX vs. NBIS - Yearly Performance Comparison

	2026 (YTD)	2025	2024
OPRX OptimizeRx Corporation	-59.62%	152.26%	-27.57%
NBIS Nebius Group N.V.	200.67%	202.18%	46.25%

Correlation

The correlation between OPRX and NBIS is 0.18, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.18
Correlation (All Time) Calculated using the full available price history since Oct 21, 2024	0.23

Fundamentals

Market Cap OPRX : $92.87M NBIS : $77.76B
EPS OPRX : $0.36 NBIS : $3.17
PE Ratio OPRX : 13.79 NBIS : 79.27
PEG Ratio OPRX : 0.02 NBIS : 27.24
PS Ratio OPRX : 0.88 NBIS : 75.53
PB Ratio OPRX : 0.72 NBIS : 10.74
Total Revenue (TTM) OPRX : $107.35M NBIS : $877.90M
Gross Profit (TTM) OPRX : $70.86M NBIS : $420.60M
EBITDA (TTM) OPRX : $16.55M NBIS : -$52.78M

Return for Risk

OPRX vs. NBIS — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

OPRX

OPRX Risk / Return Rank: 9
OPRX Sharpe Ratio Rank: 9
OPRX Sortino Ratio Rank: 8
OPRX Omega Ratio Rank: 10
OPRX Calmar Ratio Rank: 10
OPRX Martin Ratio Rank: 8

NBIS

NBIS Risk / Return Rank: 97
NBIS Sharpe Ratio Rank: 99
NBIS Sortino Ratio Rank: 96
NBIS Omega Ratio Rank: 93
NBIS Calmar Ratio Rank: 98
NBIS Martin Ratio Rank: 97

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

OPRX vs. NBIS - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for OptimizeRx Corporation (OPRX) and Nebius Group N.V. (NBIS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	OPRX	NBIS	Difference
Sharpe ratio: Return per unit of total volatility	-0.80	5.52	-6.33
Sortino ratio: Return per unit of downside risk	-1.25	4.59	-5.84
Omega ratio: Gain probability vs. loss probability	0.86	1.51	-0.66
Calmar ratio: Return relative to maximum drawdown	-0.81	12.77	-13.57
Martin ratio: Return relative to average drawdown	-1.41	29.34	-30.76
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

OPRX vs. NBIS - Sharpe Ratio Comparison

The current OPRX Sharpe Ratio is -0.80, which is lower than the NBIS Sharpe Ratio of 5.52. The chart below compares the historical Sharpe Ratios of OPRX and NBIS, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	OPRX	NBIS	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.80	5.52	-6.33
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.49	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.14	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.00	3.62	-3.62

Drawdowns

OPRX vs. NBIS - Drawdown Comparison

The maximum OPRX drawdown since its inception was -99.32%, which is greater than NBIS's maximum drawdown of -58.27%. Use the drawdown chart below to compare losses from any high point for OPRX and NBIS.

Drawdown Indicators

	OPRX	NBIS	Difference
Max Drawdown Largest peak-to-trough decline	-99.32%	-58.27%	-41.05%
Max Drawdown (1Y) Largest decline over 1 year	-77.72%	-45.47%	-32.25%
Max Drawdown (3Y) Largest decline over 3 years	-77.72%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-96.10%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-96.10%	—	—
Current Drawdown Current decline from peak	-94.95%	-4.85%	-90.10%
Average Drawdown Average peak-to-trough decline	-60.53%	-19.07%	-41.46%
Ulcer Index Depth and duration of drawdowns from previous peaks	44.32%	19.74%	+24.58%

Volatility

OPRX vs. NBIS - Volatility Comparison

The current volatility for OptimizeRx Corporation (OPRX) is 28.98%, while Nebius Group N.V. (NBIS) has a volatility of 31.82%. This indicates that OPRX experiences smaller price fluctuations and is considered to be less risky than NBIS based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	OPRX	NBIS	Difference
Volatility (1M) Calculated over the trailing 1-month period	28.98%	31.82%	-2.84%
Volatility (6M) Calculated over the trailing 6-month period	52.61%	70.20%	-17.59%
Volatility (1Y) Calculated over the trailing 1-year period	78.56%	105.12%	-26.56%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	75.83%	110.56%	-34.73%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	114.56%	110.56%	+4.00%

Dividends

OPRX vs. NBIS - Dividend Comparison

Neither OPRX nor NBIS has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both OPRX and NBIS in my portfolio?

OPRX and NBIS have a correlation of 0.18, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, OPRX or NBIS?

NBIS has higher volatility (31.82%) compared to OPRX (28.98%). In terms of maximum drawdown, OPRX dropped -99.32% vs NBIS's -58.27%.

Which has better risk-adjusted returns?

NBIS currently has the higher Sharpe Ratio (5.52 vs -0.80), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.