OPEN vs. ENTA

Last updated Jun 9, 2026

OPEN (Opendoor Technologies Inc.) and ENTA (Enanta Pharmaceuticals, Inc.) are both stocks. OPEN operates in Real Estate - Services (Real Estate), while ENTA operates in Biotechnology (Healthcare). Over the past 5 years, OPEN returned -24.01%/yr vs -25.36%/yr for ENTA. At a 0.22 correlation, their price movements are largely independent.

Performance

OPEN vs. ENTA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Opendoor Technologies Inc. (OPEN) and Enanta Pharmaceuticals, Inc. (ENTA). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, OPEN achieves a -26.07% return, which is significantly higher than ENTA's -29.80% return.

OPEN

• 1D: -2.49%
• 1M: -13.97%
• YTD: -26.07%
• 6M: -38.87%
• 1Y: 555.14%
• 3Y*: 22.89%
• 5Y*: -24.01%
• 10Y*: —

ENTA

• 1D: -1.86%
• 1M: -27.84%
• YTD: -29.80%
• 6M: -21.93%
• 1Y: 48.19%
• 3Y*: -24.76%
• 5Y*: -25.36%
• 10Y*: -7.18%

*Multi-year figures are annualized to reflect compound growth (CAGR)

OPEN vs. ENTA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
OPEN Opendoor Technologies Inc.	-26.07%	276.52%	-64.29%	286.21%	-92.06%	-35.72%	110.39%
ENTA Enanta Pharmaceuticals, Inc.	-29.80%	174.26%	-38.89%	-79.77%	-37.79%	77.62%	-14.81%

Correlation

The correlation between OPEN and ENTA is 0.14, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.14
Correlation (3Y) Calculated over the trailing 3-year period	0.21
Correlation (5Y) Calculated over the trailing 5-year period	0.23
Correlation (All Time) Calculated using the full available price history since Jun 19, 2020	0.22

Fundamentals

Market Cap OPEN : $4.13B ENTA : $319.83M
EPS OPEN : -$1.74 ENTA : -$2.67
PS Ratio OPEN : 0.87 ENTA : 3.72
PB Ratio OPEN : 4.33 ENTA : 2.77
Total Revenue (TTM) OPEN : $3.94B ENTA : $69.21M
Gross Profit (TTM) OPEN : $312.00M ENTA : $33.44M
EBITDA (TTM) OPEN : -$1.25B ENTA : -$61.85M

Return for Risk

OPEN vs. ENTA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

OPEN

OPEN Risk / Return Rank: 95
OPEN Sharpe Ratio Rank: 97
OPEN Sortino Ratio Rank: 95
OPEN Omega Ratio Rank: 92
OPEN Calmar Ratio Rank: 97
OPEN Martin Ratio Rank: 93

ENTA

ENTA Risk / Return Rank: 68
ENTA Sharpe Ratio Rank: 58
ENTA Sortino Ratio Rank: 74
ENTA Omega Ratio Rank: 73
ENTA Calmar Ratio Rank: 69
ENTA Martin Ratio Rank: 66

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

OPEN vs. ENTA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Opendoor Technologies Inc. (OPEN) and Enanta Pharmaceuticals, Inc. (ENTA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	OPEN	ENTA	Difference
Sharpe ratio: Return per unit of total volatility	3.48	0.44	+3.04
Sortino ratio: Return per unit of downside risk	4.04	1.88	+2.16
Omega ratio: Gain probability vs. loss probability	1.47	1.24	+0.23
Calmar ratio: Return relative to maximum drawdown	9.66	1.41	+8.25
Martin ratio: Return relative to average drawdown	15.03	2.72	+12.31
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

OPEN vs. ENTA - Sharpe Ratio Comparison

The current OPEN Sharpe Ratio is 3.48, which is higher than the ENTA Sharpe Ratio of 0.44. The chart below compares the historical Sharpe Ratios of OPEN and ENTA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	OPEN	ENTA	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	3.48	0.44	+3.04
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.21	-0.35	+0.13
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.12	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.13	-0.05	-0.07

Drawdowns

OPEN vs. ENTA - Drawdown Comparison

The maximum OPEN drawdown since its inception was -98.57%, roughly equal to the maximum ENTA drawdown of -96.63%. Use the drawdown chart below to compare losses from any high point for OPEN and ENTA.

Drawdown Indicators

	OPEN	ENTA	Difference
Max Drawdown Largest peak-to-trough decline	-98.57%	-96.63%	-1.94%
Max Drawdown (1Y) Largest decline over 1 year	-57.96%	-34.30%	-23.66%
Max Drawdown (3Y) Largest decline over 3 years	-90.28%	-83.61%	-6.67%
Max Drawdown (5Y) Largest decline over 5 years	-97.93%	-95.62%	-2.31%
Max Drawdown (10Y) Largest decline over 10 years	—	-96.63%	—
Current Drawdown Current decline from peak	-87.59%	-91.24%	+3.65%
Average Drawdown Average peak-to-trough decline	-74.59%	-49.23%	-25.36%
Ulcer Index Depth and duration of drawdowns from previous peaks	37.43%	17.76%	+19.67%

Volatility

OPEN vs. ENTA - Volatility Comparison

Opendoor Technologies Inc. (OPEN) has a higher volatility of 21.37% compared to Enanta Pharmaceuticals, Inc. (ENTA) at 13.36%. This indicates that OPEN's price experiences larger fluctuations and is considered to be riskier than ENTA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	OPEN	ENTA	Difference
Volatility (1M) Calculated over the trailing 1-month period	21.37%	13.36%	+8.01%
Volatility (6M) Calculated over the trailing 6-month period	52.74%	35.53%	+17.21%
Volatility (1Y) Calculated over the trailing 1-year period	161.11%	109.93%	+51.18%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	113.51%	73.36%	+40.15%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	110.45%	60.70%	+49.75%

Dividends

OPEN vs. ENTA - Dividend Comparison

Neither OPEN nor ENTA has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both OPEN and ENTA in my portfolio?

OPEN and ENTA have a correlation of 0.14, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, OPEN or ENTA?

OPEN has higher volatility (21.37%) compared to ENTA (13.36%). In terms of maximum drawdown, OPEN dropped -98.57% vs ENTA's -96.63%.

Which has better risk-adjusted returns?

OPEN currently has the higher Sharpe Ratio (3.48 vs 0.44), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.