ODFL vs. TMO

Last updated Jun 9, 2026

ODFL (Old Dominion Freight Line, Inc.) and TMO (Thermo Fisher Scientific Inc.) are both stocks. ODFL operates in Trucking (Industrials), while TMO operates in Diagnostics & Research (Healthcare). Over the past 10 years, ODFL returned 29.12%/yr vs 12.28%/yr for TMO. At a 0.26 correlation, their price movements are largely independent.

Performance

ODFL vs. TMO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Old Dominion Freight Line, Inc. (ODFL) and Thermo Fisher Scientific Inc. (TMO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ODFL achieves a 57.95% return, which is significantly higher than TMO's -18.87% return. Over the past 10 years, ODFL has outperformed TMO with an annualized return of 29.12%, while TMO has yielded a comparatively lower 12.28% annualized return.

ODFL

• 1D: 1.83%
• 1M: 24.70%
• YTD: 57.95%
• 6M: 63.28%
• 1Y: 55.07%
• 3Y*: 17.95%
• 5Y*: 15.19%
• 10Y*: 29.12%

TMO

• 1D: -0.67%
• 1M: 1.00%
• YTD: -18.87%
• 6M: -17.21%
• 1Y: 17.28%
• 3Y*: -2.93%
• 5Y*: 1.21%
• 10Y*: 12.28%

*Multi-year figures are annualized to reflect compound growth (CAGR)

ODFL vs. TMO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ODFL Old Dominion Freight Line, Inc.	57.95%	-10.47%	-12.51%	43.46%	-20.48%	84.15%	54.81%	54.36%	-5.79%	54.11%
TMO Thermo Fisher Scientific Inc.	-18.87%	11.78%	-1.72%	-3.36%	-17.29%	43.54%	43.72%	45.55%	18.21%	35.03%

Correlation

The correlation between ODFL and TMO is 0.36, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.36
Correlation (3Y) Calculated over the trailing 3-year period	0.33
Correlation (5Y) Calculated over the trailing 5-year period	0.42
Correlation (10Y) Calculated over the trailing 10-year period	0.39
Correlation (All Time) Calculated using the full available price history since Oct 25, 1991	0.26

The correlation between ODFL and TMO shifts across timeframes, from 0.26 (all time) to 0.42 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap ODFL : $51.70B TMO : $175.17B
EPS ODFL : $4.78 TMO : $18.22
PE Ratio ODFL : 51.64 TMO : 25.78
PS Ratio ODFL : 9.53 TMO : 3.91
PB Ratio ODFL : 11.75 TMO : 3.37
Total Revenue (TTM) ODFL : $5.46B TMO : $45.20B
Gross Profit (TTM) ODFL : $1.69B TMO : $17.81B
EBITDA (TTM) ODFL : $1.71B TMO : $11.16B

Return for Risk

ODFL vs. TMO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ODFL

ODFL Risk / Return Rank: 77
ODFL Sharpe Ratio Rank: 81
ODFL Sortino Ratio Rank: 76
ODFL Omega Ratio Rank: 75
ODFL Calmar Ratio Rank: 77
ODFL Martin Ratio Rank: 75

TMO

TMO Risk / Return Rank: 57
TMO Sharpe Ratio Rank: 61
TMO Sortino Ratio Rank: 57
TMO Omega Ratio Rank: 54
TMO Calmar Ratio Rank: 55
TMO Martin Ratio Rank: 55

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ODFL vs. TMO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Old Dominion Freight Line, Inc. (ODFL) and Thermo Fisher Scientific Inc. (TMO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ODFL	TMO	Difference
Sharpe ratio: Return per unit of total volatility	1.43	0.56	+0.87
Sortino ratio: Return per unit of downside risk	1.99	1.04	+0.95
Omega ratio: Gain probability vs. loss probability	1.26	1.13	+0.13
Calmar ratio: Return relative to maximum drawdown	2.12	0.55	+1.57
Martin ratio: Return relative to average drawdown	4.72	1.23	+3.49
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ODFL vs. TMO - Sharpe Ratio Comparison

The current ODFL Sharpe Ratio is 1.43, which is higher than the TMO Sharpe Ratio of 0.56. The chart below compares the historical Sharpe Ratios of ODFL and TMO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ODFL	TMO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.43	0.56	+0.87
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.42	0.04	+0.38
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.88	0.47	+0.42
Sharpe Ratio (All Time) Calculated using the full available price history	0.40	0.40	0.00

Drawdowns

ODFL vs. TMO - Drawdown Comparison

The maximum ODFL drawdown since its inception was -66.29%, smaller than the maximum TMO drawdown of -71.16%. Use the drawdown chart below to compare losses from any high point for ODFL and TMO.

Drawdown Indicators

	ODFL	TMO	Difference
Max Drawdown Largest peak-to-trough decline	-66.29%	-71.16%	+4.87%
Max Drawdown (1Y) Largest decline over 1 year	-26.06%	-31.38%	+5.32%
Max Drawdown (3Y) Largest decline over 3 years	-45.18%	-37.28%	-7.90%
Max Drawdown (5Y) Largest decline over 5 years	-45.18%	-40.95%	-4.23%
Max Drawdown (10Y) Largest decline over 10 years	-45.18%	-40.95%	-4.23%
Current Drawdown Current decline from peak	0.00%	-28.76%	+28.76%
Average Drawdown Average peak-to-trough decline	-19.10%	-18.02%	-1.08%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.69%	14.09%	-2.40%

Volatility

ODFL vs. TMO - Volatility Comparison

The current volatility for Old Dominion Freight Line, Inc. (ODFL) is 8.57%, while Thermo Fisher Scientific Inc. (TMO) has a volatility of 9.96%. This indicates that ODFL experiences smaller price fluctuations and is considered to be less risky than TMO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ODFL	TMO	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.57%	9.96%	-1.39%
Volatility (6M) Calculated over the trailing 6-month period	28.99%	21.57%	+7.42%
Volatility (1Y) Calculated over the trailing 1-year period	38.66%	31.02%	+7.64%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	36.33%	27.13%	+9.20%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	33.06%	26.33%	+6.73%

Dividends

ODFL vs. TMO - Dividend Comparison

ODFL's dividend yield for the trailing twelve months is around 0.46%, more than TMO's 0.37% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ODFL Old Dominion Freight Line, Inc.	0.46%	0.71%	0.59%	0.39%	0.42%	0.22%	0.31%	0.36%	0.42%	0.38%	0.00%	0.00%
TMO Thermo Fisher Scientific Inc.	0.37%	0.30%	0.30%	0.26%	0.22%	0.16%	0.19%	0.23%	0.30%	0.32%	0.43%	0.42%

Financials

ODFL vs. TMO - Profitability Comparison

The chart below illustrates the profitability comparison between Old Dominion Freight Line, Inc. and Thermo Fisher Scientific Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

ODFL - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Old Dominion Freight Line, Inc. reported a gross profit of 369.26M and revenue of 1.33B. Therefore, the gross margin over that period was 27.7%.

TMO - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Thermo Fisher Scientific Inc. reported a gross profit of 4.48B and revenue of 11.01B. Therefore, the gross margin over that period was 40.7%.

ODFL - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Old Dominion Freight Line, Inc. reported an operating income of 317.34M and revenue of 1.33B, resulting in an operating margin of 23.8%.

TMO - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Thermo Fisher Scientific Inc. reported an operating income of 1.86B and revenue of 11.01B, resulting in an operating margin of 16.9%.

ODFL - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Old Dominion Freight Line, Inc. reported a net income of 238.26M and revenue of 1.33B, resulting in a net margin of 17.9%.

TMO - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Thermo Fisher Scientific Inc. reported a net income of 1.65B and revenue of 11.01B, resulting in a net margin of 15.0%.

Frequently Asked Questions

Can I hold both ODFL and TMO in my portfolio?

ODFL and TMO have a correlation of 0.36, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ODFL or TMO?

TMO has higher volatility (9.96%) compared to ODFL (8.57%). In terms of maximum drawdown, ODFL dropped -66.29% vs TMO's -71.16%.

Which has better risk-adjusted returns?

ODFL currently has the higher Sharpe Ratio (1.43 vs 0.56), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.