TMO vs. A

Last updated Apr 2, 2026

Compare and contrast key facts about Thermo Fisher Scientific Inc. (TMO) and Agilent Technologies, Inc. (A).

Performance

TMO vs. A - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Thermo Fisher Scientific Inc. (TMO) and Agilent Technologies, Inc. (A). The values are adjusted to include any dividend payments, if applicable.

TMO vs. A - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
TMO Thermo Fisher Scientific Inc.	-14.57%	11.78%	-1.72%	-3.36%	-17.29%	43.54%	43.72%	45.55%	18.21%	35.03%
A Agilent Technologies, Inc.	-15.48%	1.92%	-2.70%	-6.42%	-5.52%	35.51%	39.79%	27.54%	1.67%	48.32%

Fundamentals

Market Cap TMO : $186.44B A : $32.53B
EPS TMO : $17.77 A : $4.53
PE Ratio TMO : 27.83 A : 25.26
PS Ratio TMO : 4.19 A : 4.61
PB Ratio TMO : 3.49 A : 4.71
Total Revenue (TTM) TMO : $44.56B A : $7.07B
Gross Profit (TTM) TMO : $18.02B A : $2.74B
EBITDA (TTM) TMO : $11.35B A : $1.72B

Returns By Period

In the year-to-date period, TMO achieves a -14.57% return, which is significantly higher than A's -15.48% return. Over the past 10 years, TMO has outperformed A with an annualized return of 13.56%, while A has yielded a comparatively lower 11.89% annualized return.

TMO

• 1D: 0.61%
• 1M: -2.66%
• YTD: -14.57%
• 6M: -6.66%
• 1Y: 2.77%
• 3Y*: -4.68%
• 5Y*: 1.90%
• 10Y*: 13.56%

A

• 1D: 0.49%
• 1M: -2.85%
• YTD: -15.48%
• 6M: -17.01%
• 1Y: 1.25%
• 3Y*: -5.33%
• 5Y*: -1.44%
• 10Y*: 11.89%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

TMO vs. A — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TMO

TMO Risk / Return Rank: 39
TMO Sharpe Ratio Rank: 43
TMO Sortino Ratio Rank: 38
TMO Omega Ratio Rank: 37
TMO Calmar Ratio Rank: 40
TMO Martin Ratio Rank: 40

A

A Risk / Return Rank: 38
A Sharpe Ratio Rank: 41
A Sortino Ratio Rank: 35
A Omega Ratio Rank: 35
A Calmar Ratio Rank: 39
A Martin Ratio Rank: 39

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

TMO vs. A - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Thermo Fisher Scientific Inc. (TMO) and Agilent Technologies, Inc. (A). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	TMO	A	Difference
Sharpe ratio Return per unit of total volatility	0.09	0.04	+0.05
Sortino ratio Return per unit of downside risk	0.38	0.29	+0.09
Omega ratio Gain probability vs. loss probability	1.04	1.03	+0.01
Calmar ratio Return relative to maximum drawdown	-0.01	-0.04	+0.03
Martin ratio Return relative to average drawdown	-0.02	-0.09	+0.07
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

TMO vs. A - Sharpe Ratio Comparison

The current TMO Sharpe Ratio is 0.09, which is higher than the A Sharpe Ratio of 0.04. The chart below compares the historical Sharpe Ratios of TMO and A, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	TMO	A	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.09	0.04	+0.05
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.07	-0.05	+0.12
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.52	0.43	+0.09
Sharpe Ratio (All Time) Calculated using the full available price history	0.41	0.14	+0.27

Correlation

The correlation between TMO and A is 0.58, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.

Dividends

TMO vs. A - Dividend Comparison

TMO's dividend yield for the trailing twelve months is around 0.36%, less than A's 0.88% yield.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
TMO Thermo Fisher Scientific Inc.	0.36%	0.30%	0.30%	0.26%	0.22%	0.16%	0.19%	0.23%	0.30%	0.32%	0.43%	0.42%
A Agilent Technologies, Inc.	0.88%	0.55%	0.71%	0.66%	0.71%	0.49%	0.46%	0.79%	0.91%	0.81%	1.05%	1.23%

Drawdowns

TMO vs. A - Drawdown Comparison

The maximum TMO drawdown since its inception was -71.16%, smaller than the maximum A drawdown of -93.18%. Use the drawdown chart below to compare losses from any high point for TMO and A.

Drawdown Indicators

	TMO	A	Difference
Max Drawdown Largest peak-to-trough decline	-71.16%	-93.18%	+22.02%
Max Drawdown (1Y) Largest decline over 1 year	-27.31%	-29.75%	+2.44%
Max Drawdown (5Y) Largest decline over 5 years	-40.95%	-43.19%	+2.24%
Max Drawdown (10Y) Largest decline over 10 years	-40.95%	-43.19%	+2.24%
Current Drawdown Current decline from peak	-24.98%	-33.93%	+8.95%
Average Drawdown Average peak-to-trough decline	-17.97%	-57.45%	+39.48%
Ulcer Index Depth and duration of drawdowns from previous peaks	12.13%	11.50%	+0.63%

Volatility

TMO vs. A - Volatility Comparison

Thermo Fisher Scientific Inc. (TMO) has a higher volatility of 8.84% compared to Agilent Technologies, Inc. (A) at 7.15%. This indicates that TMO's price experiences larger fluctuations and is considered to be riskier than A based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	TMO	A	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.84%	7.15%	+1.69%
Volatility (6M) Calculated over the trailing 6-month period	19.06%	19.15%	-0.09%
Volatility (1Y) Calculated over the trailing 1-year period	32.87%	31.81%	+1.06%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	26.59%	28.60%	-2.01%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.93%	27.44%	-1.51%

Financials

TMO vs. A - Profitability Comparison

The chart below illustrates the profitability comparison between Thermo Fisher Scientific Inc. and Agilent Technologies, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

TMO - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Thermo Fisher Scientific Inc. reported a gross profit of 5.07B and revenue of 12.22B. Therefore, the gross margin over that period was 41.5%.

A - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Agilent Technologies, Inc. reported a gross profit of 0.00 and revenue of 1.80B. Therefore, the gross margin over that period was 0.0%.

TMO - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Thermo Fisher Scientific Inc. reported an operating income of 2.26B and revenue of 12.22B, resulting in an operating margin of 18.5%.

A - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Agilent Technologies, Inc. reported an operating income of 353.00M and revenue of 1.80B, resulting in an operating margin of 19.6%.

TMO - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Thermo Fisher Scientific Inc. reported a net income of 1.97B and revenue of 12.22B, resulting in a net margin of 16.1%.

A - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Agilent Technologies, Inc. reported a net income of 305.00M and revenue of 1.80B, resulting in a net margin of 17.0%.