TMO vs. DHR

Last updated Apr 2, 2026

Compare and contrast key facts about Thermo Fisher Scientific Inc. (TMO) and Danaher Corporation (DHR).

Performance

TMO vs. DHR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Thermo Fisher Scientific Inc. (TMO) and Danaher Corporation (DHR). The values are adjusted to include any dividend payments, if applicable.

TMO vs. DHR - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
TMO Thermo Fisher Scientific Inc.	-14.57%	11.78%	-1.72%	-3.36%	-17.29%	43.54%	43.72%	45.55%	18.21%	35.03%
DHR Danaher Corporation	-16.48%	0.35%	-0.35%	-1.22%	-19.02%	48.57%	45.34%	49.55%	11.80%	20.01%

Fundamentals

Market Cap TMO : $186.44B DHR : $135.65B
EPS TMO : $17.77 DHR : $5.06
PE Ratio TMO : 27.83 DHR : 37.73
PS Ratio TMO : 4.19 DHR : 5.55
PB Ratio TMO : 3.49 DHR : 2.58
Total Revenue (TTM) TMO : $44.56B DHR : $24.57B
Gross Profit (TTM) TMO : $18.02B DHR : $14.97B
EBITDA (TTM) TMO : $11.35B DHR : $7.02B

Returns By Period

In the year-to-date period, TMO achieves a -14.57% return, which is significantly higher than DHR's -16.48% return. Over the past 10 years, TMO has outperformed DHR with an annualized return of 13.56%, while DHR has yielded a comparatively lower 12.07% annualized return.

TMO

• 1D: 0.61%
• 1M: -2.66%
• YTD: -14.57%
• 6M: -6.66%
• 1Y: 2.77%
• 3Y*: -4.68%
• 5Y*: 1.90%
• 10Y*: 13.56%

DHR

• 1D: 0.63%
• 1M: -7.19%
• YTD: -16.48%
• 6M: -10.06%
• 1Y: -4.13%
• 3Y*: -4.61%
• 5Y*: -0.43%
• 10Y*: 12.07%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

TMO vs. DHR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TMO

TMO Risk / Return Rank: 39
TMO Sharpe Ratio Rank: 43
TMO Sortino Ratio Rank: 38
TMO Omega Ratio Rank: 37
TMO Calmar Ratio Rank: 40
TMO Martin Ratio Rank: 40

DHR

DHR Risk / Return Rank: 31
DHR Sharpe Ratio Rank: 34
DHR Sortino Ratio Rank: 30
DHR Omega Ratio Rank: 30
DHR Calmar Ratio Rank: 33
DHR Martin Ratio Rank: 28

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

TMO vs. DHR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Thermo Fisher Scientific Inc. (TMO) and Danaher Corporation (DHR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	TMO	DHR	Difference
Sharpe ratio Return per unit of total volatility	0.09	-0.13	+0.21
Sortino ratio Return per unit of downside risk	0.38	0.04	+0.33
Omega ratio Gain probability vs. loss probability	1.04	1.01	+0.04
Calmar ratio Return relative to maximum drawdown	-0.01	-0.25	+0.24
Martin ratio Return relative to average drawdown	-0.02	-0.75	+0.72
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

TMO vs. DHR - Sharpe Ratio Comparison

The current TMO Sharpe Ratio is 0.09, which is higher than the DHR Sharpe Ratio of -0.13. The chart below compares the historical Sharpe Ratios of TMO and DHR, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	TMO	DHR	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.09	-0.13	+0.21
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.07	-0.02	+0.09
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.52	0.48	+0.05
Sharpe Ratio (All Time) Calculated using the full available price history	0.41	0.66	-0.25

Correlation

The correlation between TMO and DHR is 0.44, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.

Dividends

TMO vs. DHR - Dividend Comparison

TMO's dividend yield for the trailing twelve months is around 0.36%, less than DHR's 0.71% yield.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
TMO Thermo Fisher Scientific Inc.	0.36%	0.30%	0.30%	0.26%	0.22%	0.16%	0.19%	0.23%	0.30%	0.32%	0.43%	0.42%
DHR Danaher Corporation	0.71%	0.56%	0.47%	12.64%	0.38%	0.26%	0.32%	0.44%	0.62%	0.60%	32.55%	0.58%

Drawdowns

TMO vs. DHR - Drawdown Comparison

The maximum TMO drawdown since its inception was -71.16%, which is greater than DHR's maximum drawdown of -45.80%. Use the drawdown chart below to compare losses from any high point for TMO and DHR.

Drawdown Indicators

	TMO	DHR	Difference
Max Drawdown Largest peak-to-trough decline	-71.16%	-45.80%	-25.36%
Max Drawdown (1Y) Largest decline over 1 year	-27.31%	-24.85%	-2.46%
Max Drawdown (5Y) Largest decline over 5 years	-40.95%	-39.81%	-1.14%
Max Drawdown (10Y) Largest decline over 10 years	-40.95%	-39.81%	-1.14%
Current Drawdown Current decline from peak	-24.98%	-33.79%	+8.81%
Average Drawdown Average peak-to-trough decline	-17.97%	-10.09%	-7.88%
Ulcer Index Depth and duration of drawdowns from previous peaks	12.13%	8.44%	+3.69%

Volatility

TMO vs. DHR - Volatility Comparison

Thermo Fisher Scientific Inc. (TMO) and Danaher Corporation (DHR) have volatilities of 8.84% and 8.96%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	TMO	DHR	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.84%	8.96%	-0.12%
Volatility (6M) Calculated over the trailing 6-month period	19.06%	19.14%	-0.08%
Volatility (1Y) Calculated over the trailing 1-year period	32.87%	32.46%	+0.41%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	26.59%	27.75%	-1.16%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.93%	25.24%	+0.69%

Financials

TMO vs. DHR - Profitability Comparison

The chart below illustrates the profitability comparison between Thermo Fisher Scientific Inc. and Danaher Corporation over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

TMO - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Thermo Fisher Scientific Inc. reported a gross profit of 5.07B and revenue of 12.22B. Therefore, the gross margin over that period was 41.5%.

DHR - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Danaher Corporation reported a gross profit of 3.97B and revenue of 6.84B. Therefore, the gross margin over that period was 58.0%.

TMO - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Thermo Fisher Scientific Inc. reported an operating income of 2.26B and revenue of 12.22B, resulting in an operating margin of 18.5%.

DHR - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Danaher Corporation reported an operating income of 1.50B and revenue of 6.84B, resulting in an operating margin of 22.0%.

TMO - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Thermo Fisher Scientific Inc. reported a net income of 1.97B and revenue of 12.22B, resulting in a net margin of 16.1%.

DHR - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Danaher Corporation reported a net income of 1.20B and revenue of 6.84B, resulting in a net margin of 17.5%.