NTLA vs. MSFT
NTLA (Intellia Therapeutics, Inc.) and MSFT (Microsoft Corporation) are both stocks. NTLA operates in Biotechnology (Healthcare), while MSFT operates in Software - Infrastructure (Technology). Over the past 10 years, NTLA returned -7.62%/yr vs 24.39%/yr for MSFT. At a 0.30 correlation, their price movements are largely independent.
Performance
NTLA vs. MSFT - Performance Comparison
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Returns By Period
In the year-to-date period, NTLA achieves a 34.71% return, which is significantly higher than MSFT's -18.85% return. Over the past 10 years, NTLA has underperformed MSFT with an annualized return of -7.62%, while MSFT has yielded a comparatively higher 24.39% annualized return.
NTLA
- 1D
- -1.94%
- 1M
- -7.49%
- YTD
- 34.71%
- 6M
- 34.26%
- 1Y
- 45.73%
- 3Y*
- -35.92%
- 5Y*
- -32.32%
- 10Y*
- -7.62%
MSFT
- 1D
- 0.10%
- 1M
- -7.19%
- YTD
- -18.85%
- 6M
- -17.98%
- 1Y
- -17.07%
- 3Y*
- 6.16%
- 5Y*
- 9.56%
- 10Y*
- 24.39%
NTLA vs. MSFT - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
NTLA Intellia Therapeutics, Inc. | 34.71% | -22.90% | -61.76% | -12.61% | -70.49% | 117.35% | 270.82% | 7.47% | -28.98% | 46.61% |
MSFT Microsoft Corporation | -18.85% | 15.58% | 12.93% | 58.19% | -28.02% | 52.48% | 42.53% | 57.56% | 20.80% | 40.73% |
Correlation
The correlation between NTLA and MSFT is 0.11, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.11 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.17 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.29 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.30 |
Correlation (All Time) Calculated using the full available price history since May 6, 2016 | 0.30 |
The correlation between NTLA and MSFT shifts across timeframes, from 0.11 (1 year) to 0.30 (10 years), reflecting how their relationship changes across market environments.
Fundamentals
NTLA:
$1.43B
MSFT:
$2.91T
NTLA:
-$3.58
MSFT:
$16.79
NTLA:
20.19
MSFT:
9.16
NTLA:
2.31
MSFT:
7.02
NTLA:
$66.09M
MSFT:
$318.27B
NTLA:
-$33.92M
MSFT:
$217.41B
NTLA:
-$299.32M
MSFT:
$200.96B
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Return for Risk
NTLA vs. MSFT — Risk / Return Rank
NTLA
MSFT
NTLA vs. MSFT - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Intellia Therapeutics, Inc. (NTLA) and Microsoft Corporation (MSFT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| NTLA | MSFT | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.17 | ||
| Sortino ratioReturn per unit of downside risk | +2.12 | ||
| Omega ratioGain probability vs. loss probability | 1.18 | 0.89 | +0.29 |
| Calmar ratioReturn relative to maximum drawdown | 0.63 | -0.53 | +1.16 |
| Martin ratioReturn relative to average drawdown | 0.99 | -1.08 | +2.06 |
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Drawdowns
NTLA vs. MSFT - Drawdown Comparison
The maximum NTLA drawdown since its inception was -96.45%, which is greater than MSFT's maximum drawdown of -69.38%. Use the drawdown chart below to compare losses from any high point for NTLA and MSFT.
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Drawdown Indicators
| NTLA | MSFT | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -96.45% | -69.38% | -27.07% |
Max Drawdown (1Y)Largest decline over 1 year | -71.27% | -33.91% | -37.36% |
Max Drawdown (3Y)Largest decline over 3 years | -86.28% | -33.91% | -52.37% |
Max Drawdown (5Y)Largest decline over 5 years | -96.45% | -37.15% | -59.30% |
Max Drawdown (10Y)Largest decline over 10 years | -96.45% | -37.15% | -59.30% |
Current DrawdownCurrent decline from peak | -93.15% | -27.46% | -65.69% |
Average DrawdownAverage peak-to-trough decline | -57.11% | -21.78% | -35.33% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 45.80% | 16.48% | +29.32% |
Volatility
NTLA vs. MSFT - Volatility Comparison
Intellia Therapeutics, Inc. (NTLA) has a higher volatility of 24.01% compared to Microsoft Corporation (MSFT) at 10.52%. This indicates that NTLA's price experiences larger fluctuations and is considered to be riskier than MSFT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| NTLA | MSFT | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 24.01% | 10.52% | +13.49% |
Volatility (6M)Calculated over the trailing 6-month period | 54.68% | 22.31% | +32.37% |
Volatility (1Y)Calculated over the trailing 1-year period | 96.60% | 25.42% | +71.18% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 80.85% | 26.66% | +54.19% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 78.41% | 27.06% | +51.35% |
Dividends
NTLA vs. MSFT - Dividend Comparison
NTLA has not paid dividends to shareholders, while MSFT's dividend yield for the trailing twelve months is around 0.91%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MSFT Microsoft Corporation | 0.91% | 0.70% | 0.73% | 0.74% | 1.06% | 0.68% | 0.94% | 1.20% | 1.69% | 1.86% | 2.37% | 2.33% |
NTLA Intellia Therapeutics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
NTLA vs. MSFT - Financials Comparison
This section allows you to compare key financial metrics between Intellia Therapeutics, Inc. and Microsoft Corporation. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
NTLA and MSFT have a correlation of 0.11, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
NTLA has higher volatility (24.01%) compared to MSFT (10.52%). In terms of maximum drawdown, NTLA dropped -96.45% vs MSFT's -69.38%.
NTLA currently has the higher Sharpe Ratio (0.47 vs -0.70), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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