NTLA vs. AAPL

Last updated Jun 3, 2026

NTLA (Intellia Therapeutics, Inc.) and AAPL (Apple Inc) are both stocks. NTLA operates in Biotechnology (Healthcare), while AAPL operates in Consumer Electronics (Technology). Over the past 10 years, NTLA returned -7.55%/yr vs 30.33%/yr for AAPL. At a 0.32 correlation, their price movements are largely independent.

Performance

NTLA vs. AAPL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Intellia Therapeutics, Inc. (NTLA) and Apple Inc (AAPL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, NTLA achieves a 46.05% return, which is significantly higher than AAPL's 16.16% return. Over the past 10 years, NTLA has underperformed AAPL with an annualized return of -7.55%, while AAPL has yielded a comparatively higher 30.33% annualized return.

NTLA

• 1D: -4.37%
• 1M: -0.98%
• YTD: 46.05%
• 6M: 62.10%
• 1Y: 83.38%
• 3Y*: -31.56%
• 5Y*: -28.75%
• 10Y*: -7.55%

AAPL

• 1D: 2.90%
• 1M: 12.62%
• YTD: 16.16%
• 6M: 10.34%
• 1Y: 56.89%
• 3Y*: 20.88%
• 5Y*: 21.22%
• 10Y*: 30.33%

*Multi-year figures are annualized to reflect compound growth (CAGR)

NTLA vs. AAPL - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
NTLA Intellia Therapeutics, Inc.	46.05%	-22.90%	-61.76%	-12.61%	-70.49%	117.35%	270.82%	7.47%	-28.98%	46.61%
AAPL Apple Inc	16.16%	9.05%	30.71%	49.01%	-26.40%	34.65%	82.31%	88.96%	-5.39%	48.46%

Correlation

The correlation between NTLA and AAPL is 0.20, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.20
Correlation (3Y) Calculated over the trailing 3-year period	0.23
Correlation (5Y) Calculated over the trailing 5-year period	0.32
Correlation (10Y) Calculated over the trailing 10-year period	0.32
Correlation (All Time) Calculated using the full available price history since May 9, 2016	0.32

The correlation between NTLA and AAPL shifts across timeframes, from 0.20 (1 year) to 0.32 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap NTLA : $1.56B AAPL : $4.65T
EPS NTLA : -$3.58 AAPL : $8.24
PS Ratio NTLA : 21.89 AAPL : 10.39
PB Ratio NTLA : 2.51 AAPL : 43.71
Total Revenue (TTM) NTLA : $66.09M AAPL : $451.44B
Gross Profit (TTM) NTLA : -$33.92M AAPL : $216.07B
EBITDA (TTM) NTLA : -$299.32M AAPL : $153.63B

Return for Risk

NTLA vs. AAPL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NTLA

NTLA Risk / Return Rank: 66
NTLA Sharpe Ratio Rank: 68
NTLA Sortino Ratio Rank: 67
NTLA Omega Ratio Rank: 71
NTLA Calmar Ratio Rank: 65
NTLA Martin Ratio Rank: 60

AAPL

AAPL Risk / Return Rank: 90
AAPL Sharpe Ratio Rank: 92
AAPL Sortino Ratio Rank: 92
AAPL Omega Ratio Rank: 91
AAPL Calmar Ratio Rank: 88
AAPL Martin Ratio Rank: 88

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NTLA vs. AAPL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Intellia Therapeutics, Inc. (NTLA) and Apple Inc (AAPL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	NTLA	AAPL	Difference
Sharpe ratio Return per unit of total volatility	0.88	2.57	-1.69
Sortino ratio Return per unit of downside risk	1.63	3.56	-1.93
Omega ratio Gain probability vs. loss probability	1.24	1.46	-0.22
Calmar ratio Return relative to maximum drawdown	1.28	4.17	-2.89
Martin ratio Return relative to average drawdown	2.03	10.52	-8.49
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

NTLA vs. AAPL - Sharpe Ratio Comparison

The current NTLA Sharpe Ratio is 0.88, which is lower than the AAPL Sharpe Ratio of 2.57. The chart below compares the historical Sharpe Ratios of NTLA and AAPL, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	NTLA	AAPL	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.88	2.57	-1.69
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.36	0.78	-1.14
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.10	1.05	-1.15
Sharpe Ratio (All Time) Calculated using the full available price history	-0.06	0.44	-0.51

Drawdowns

NTLA vs. AAPL - Drawdown Comparison

The maximum NTLA drawdown since its inception was -96.45%, which is greater than AAPL's maximum drawdown of -81.80%. Use the drawdown chart below to compare losses from any high point for NTLA and AAPL.

Drawdown Indicators

	NTLA	AAPL	Difference
Max Drawdown Largest peak-to-trough decline	-96.45%	-81.80%	-14.65%
Max Drawdown (1Y) Largest decline over 1 year	-71.27%	-13.80%	-57.47%
Max Drawdown (3Y) Largest decline over 3 years	-86.36%	-33.36%	-53.00%
Max Drawdown (5Y) Largest decline over 5 years	-96.45%	-33.36%	-63.09%
Max Drawdown (10Y) Largest decline over 10 years	-96.45%	-38.52%	-57.93%
Current Drawdown Current decline from peak	-92.57%	0.00%	-92.57%
Average Drawdown Average peak-to-trough decline	-57.02%	-29.61%	-27.41%
Ulcer Index Depth and duration of drawdowns from previous peaks	44.80%	5.47%	+39.33%

Volatility

NTLA vs. AAPL - Volatility Comparison

Intellia Therapeutics, Inc. (NTLA) has a higher volatility of 19.33% compared to Apple Inc (AAPL) at 5.32%. This indicates that NTLA's price experiences larger fluctuations and is considered to be riskier than AAPL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	NTLA	AAPL	Difference
Volatility (1M) Calculated over the trailing 1-month period	19.33%	5.32%	+14.01%
Volatility (6M) Calculated over the trailing 6-month period	54.23%	15.89%	+38.34%
Volatility (1Y) Calculated over the trailing 1-year period	95.62%	22.25%	+73.37%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	80.62%	27.46%	+53.16%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	78.27%	28.89%	+49.38%

Dividends

NTLA vs. AAPL - Dividend Comparison

NTLA has not paid dividends to shareholders, while AAPL's dividend yield for the trailing twelve months is around 0.33%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
AAPL Apple Inc	0.33%	0.38%	0.40%	0.49%	0.70%	0.49%	0.61%	1.04%	1.79%	1.45%	1.93%	1.93%
NTLA Intellia Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both NTLA and AAPL in my portfolio?

NTLA and AAPL have a correlation of 0.20, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, NTLA or AAPL?

NTLA has higher volatility (19.33%) compared to AAPL (5.32%). In terms of maximum drawdown, NTLA dropped -96.45% vs AAPL's -81.80%.

Which has better risk-adjusted returns?

AAPL currently has the higher Sharpe Ratio (2.57 vs 0.88), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.