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NTLA vs. PRME
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Correlation

The correlation between NTLA and PRME is 0.37, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


Performance

NTLA vs. PRME - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Intellia Therapeutics, Inc. (NTLA) and Prime Medicine Inc. Common Stock (PRME). The values are adjusted to include any dividend payments, if applicable.

-90.00%-85.00%-80.00%-75.00%-70.00%-65.00%December2025FebruaryMarchAprilMay
-83.24%
-91.41%
NTLA
PRME

Key characteristics

Sharpe Ratio

NTLA:

-0.87

PRME:

-0.80

Sortino Ratio

NTLA:

-1.43

PRME:

-1.47

Omega Ratio

NTLA:

0.84

PRME:

0.84

Calmar Ratio

NTLA:

-0.67

PRME:

-0.80

Martin Ratio

NTLA:

-1.43

PRME:

-1.34

Ulcer Index

NTLA:

45.68%

PRME:

56.27%

Daily Std Dev

NTLA:

73.44%

PRME:

93.92%

Max Drawdown

NTLA:

-96.45%

PRME:

-94.55%

Current Drawdown

NTLA:

-95.32%

PRME:

-93.75%

Fundamentals

Market Cap

NTLA:

$915.67M

PRME:

$220.35M

EPS

NTLA:

-$5.25

PRME:

-$1.65

PS Ratio

NTLA:

15.46

PRME:

73.87

PB Ratio

NTLA:

1.03

PRME:

1.44

Total Revenue (TTM)

NTLA:

$28.94M

PRME:

$40.17M

Gross Profit (TTM)

NTLA:

$23.78M

PRME:

$38.45M

EBITDA (TTM)

NTLA:

-$412.49M

PRME:

-$149.31M

Returns By Period

In the year-to-date period, NTLA achieves a -28.99% return, which is significantly higher than PRME's -54.79% return.


NTLA

YTD

-28.99%

1M

31.85%

6M

-48.25%

1Y

-64.00%

5Y*

-9.53%

10Y*

N/A

PRME

YTD

-54.79%

1M

14.78%

6M

-67.80%

1Y

-75.37%

5Y*

N/A

10Y*

N/A

*Annualized

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Risk-Adjusted Performance

NTLA vs. PRME — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NTLA
The Risk-Adjusted Performance Rank of NTLA is 99
Overall Rank
The Sharpe Ratio Rank of NTLA is 88
Sharpe Ratio Rank
The Sortino Ratio Rank of NTLA is 77
Sortino Ratio Rank
The Omega Ratio Rank of NTLA is 1010
Omega Ratio Rank
The Calmar Ratio Rank of NTLA is 1111
Calmar Ratio Rank
The Martin Ratio Rank of NTLA is 1010
Martin Ratio Rank

PRME
The Risk-Adjusted Performance Rank of PRME is 99
Overall Rank
The Sharpe Ratio Rank of PRME is 1010
Sharpe Ratio Rank
The Sortino Ratio Rank of PRME is 66
Sortino Ratio Rank
The Omega Ratio Rank of PRME is 1010
Omega Ratio Rank
The Calmar Ratio Rank of PRME is 55
Calmar Ratio Rank
The Martin Ratio Rank of PRME is 1313
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

NTLA vs. PRME - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Intellia Therapeutics, Inc. (NTLA) and Prime Medicine Inc. Common Stock (PRME). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current NTLA Sharpe Ratio is -0.87, which is comparable to the PRME Sharpe Ratio of -0.80. The chart below compares the historical Sharpe Ratios of NTLA and PRME, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.20-1.00-0.80-0.60-0.40December2025FebruaryMarchAprilMay
-0.87
-0.80
NTLA
PRME

Dividends

NTLA vs. PRME - Dividend Comparison

Neither NTLA nor PRME has paid dividends to shareholders.


Tickers have no history of dividend payments

Drawdowns

NTLA vs. PRME - Drawdown Comparison

The maximum NTLA drawdown since its inception was -96.45%, roughly equal to the maximum PRME drawdown of -94.55%. Use the drawdown chart below to compare losses from any high point for NTLA and PRME. For additional features, visit the drawdowns tool.


-95.00%-90.00%-85.00%-80.00%-75.00%-70.00%December2025FebruaryMarchAprilMay
-84.93%
-93.75%
NTLA
PRME

Volatility

NTLA vs. PRME - Volatility Comparison

The current volatility for Intellia Therapeutics, Inc. (NTLA) is 30.95%, while Prime Medicine Inc. Common Stock (PRME) has a volatility of 37.93%. This indicates that NTLA experiences smaller price fluctuations and is considered to be less risky than PRME based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


15.00%20.00%25.00%30.00%35.00%40.00%December2025FebruaryMarchAprilMay
30.95%
37.93%
NTLA
PRME

Financials

NTLA vs. PRME - Financials Comparison

This section allows you to compare key financial metrics between Intellia Therapeutics, Inc. and Prime Medicine Inc. Common Stock. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.0010.00M20.00M30.00M40.00MAprilJulyOctober2021AprilJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober
12.87M
2.18M
(NTLA) Total Revenue
(PRME) Total Revenue
Values in USD except per share items