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NBIX vs. OR
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

NBIX vs. OR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Neurocrine Biosciences, Inc. (NBIX) and Osisko Gold Royalties Ltd (OR). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, NBIX achieves a 24.87% return, which is significantly higher than OR's -16.97% return. Over the past 10 years, NBIX has outperformed OR with an annualized return of 13.85%, while OR has yielded a comparatively lower 9.90% annualized return.


NBIX

1D
-1.91%
1M
8.85%
6M
30.43%
YTD
24.87%
1Y
32.71%
3Y*
21.73%
5Y*
12.33%
10Y*
13.85%

OR

1D
-1.58%
1M
-10.39%
6M
-23.87%
YTD
-16.97%
1Y
5.75%
3Y*
28.20%
5Y*
18.38%
10Y*
9.90%
*Multi-year figures are annualized to reflect compound growth (CAGR)

NBIX vs. OR - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
NBIX
Neurocrine Biosciences, Inc.
24.87%3.90%3.60%10.31%40.24%-11.14%-10.83%50.53%-7.96%100.49%
OR
Osisko Gold Royalties Ltd
-16.97%96.95%28.14%19.96%0.02%-2.01%32.58%12.20%-22.72%20.74%

Correlation

The correlation between NBIX and OR is -0.03, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

-0.03

Correlation (3Y)
Calculated over the trailing 3-year period

0.02

Correlation (5Y)
Calculated over the trailing 5-year period

0.07

Correlation (10Y)
Calculated over the trailing 10-year period

0.04

Correlation (All Time)
Calculated using the full available price history since Jan 4, 2016

0.04

The correlation between NBIX and OR shifts across timeframes, from -0.03 (1 year) to 0.07 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

NBIX:

$17.81B

OR:

$5.49B

EPS

NBIX:

$6.50

OR:

$1.34

PE Ratio

NBIX:

27.23

OR:

21.81

PEG Ratio

NBIX:

0.54

OR:

0.12

PS Ratio

NBIX:

5.87

OR:

17.03

PB Ratio

NBIX:

5.37

OR:

3.74

Total Revenue (TTM)

NBIX:

$3.10B

OR:

$325.18M

Gross Profit (TTM)

NBIX:

$3.05B

OR:

$275.03M

EBITDA (TTM)

NBIX:

$881.20M

OR:

$330.83M

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Return for Risk

NBIX vs. OR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NBIX
NBIX Risk / Return Rank: 7373
Overall Rank
NBIX Sharpe Ratio Rank: 7676
Sharpe Ratio Rank
NBIX Sortino Ratio Rank: 7171
Sortino Ratio Rank
NBIX Omega Ratio Rank: 7171
Omega Ratio Rank
NBIX Calmar Ratio Rank: 7373
Calmar Ratio Rank
NBIX Martin Ratio Rank: 7272
Martin Ratio Rank

OR
OR Risk / Return Rank: 5252
Overall Rank
OR Sharpe Ratio Rank: 5353
Sharpe Ratio Rank
OR Sortino Ratio Rank: 4949
Sortino Ratio Rank
OR Omega Ratio Rank: 5050
Omega Ratio Rank
OR Calmar Ratio Rank: 5252
Calmar Ratio Rank
OR Martin Ratio Rank: 5353
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NBIX vs. OR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Neurocrine Biosciences, Inc. (NBIX) and Osisko Gold Royalties Ltd (OR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


NBIXORDifference
Sharpe ratioReturn per unit of total volatility

+0.77

Sortino ratioReturn per unit of downside risk

+0.91

Omega ratioGain probability vs. loss probability

1.20

1.08

+0.12

Calmar ratioReturn relative to maximum drawdown

1.50

0.26

+1.24

Martin ratioReturn relative to average drawdown

3.29

0.60

+2.69

NBIX vs. OR - Sharpe Ratio Comparison

The current NBIX Sharpe Ratio is 0.99, which is higher than the OR Sharpe Ratio of 0.22. The chart below compares the historical Sharpe Ratios of NBIX and OR, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

NBIX vs. OR - Drawdown Comparison

The maximum NBIX drawdown since its inception was -97.21%, which is greater than OR's maximum drawdown of -61.90%. Use the drawdown chart below to compare losses from any high point for NBIX and OR.


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Drawdown Indicators


NBIXORDifference

Max Drawdown

Largest peak-to-trough decline

-97.21%

-61.90%

-35.31%

Max Drawdown (1Y)

Largest decline over 1 year

-20.90%

-38.54%

+17.64%

Max Drawdown (3Y)

Largest decline over 3 years

-42.89%

-38.54%

-4.35%

Max Drawdown (5Y)

Largest decline over 5 years

-42.89%

-38.54%

-4.35%

Max Drawdown (10Y)

Largest decline over 10 years

-46.39%

-61.90%

+15.51%

Current Drawdown

Current decline from peak

-1.91%

-38.43%

+36.52%

Average Drawdown

Average peak-to-trough decline

-43.74%

-18.16%

-25.58%

Ulcer Index

Depth and duration of drawdowns from previous peaks

9.52%

16.70%

-7.18%

Volatility

NBIX vs. OR - Volatility Comparison

The current volatility for Neurocrine Biosciences, Inc. (NBIX) is 8.08%, while Osisko Gold Royalties Ltd (OR) has a volatility of 13.74%. This indicates that NBIX experiences smaller price fluctuations and is considered to be less risky than OR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


NBIXORDifference

Volatility (1M)

Calculated over the trailing 1-month period

8.08%

13.74%

-5.66%

Volatility (6M)

Calculated over the trailing 6-month period

23.42%

38.47%

-15.05%

Volatility (1Y)

Calculated over the trailing 1-year period

31.73%

45.74%

-14.01%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

32.83%

36.04%

-3.21%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

39.03%

38.60%

+0.43%

Dividends

NBIX vs. OR - Dividend Comparison

NBIX has not paid dividends to shareholders, while OR's dividend yield for the trailing twelve months is around 0.79%.


PositionTTM2025202420232022202120202019201820172016
NBIX
Neurocrine Biosciences, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
OR
Osisko Gold Royalties Ltd
0.79%0.59%1.02%1.34%1.38%1.37%1.18%1.56%1.72%1.56%1.65%

Financials

NBIX vs. OR - Financials Comparison

This section allows you to compare key financial metrics between Neurocrine Biosciences, Inc. and Osisko Gold Royalties Ltd. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00200.00M400.00M600.00M800.00MJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober2026
814.50M
101.41M
(NBIX) Total Revenue
(OR) Total Revenue
Values in USD except per share items

NBIX vs. OR - Profitability Comparison

The chart below illustrates the profitability comparison between Neurocrine Biosciences, Inc. and Osisko Gold Royalties Ltd over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

60.0%70.0%80.0%90.0%100.0%JulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober2026
98.3%
86.1%
Portfolio components
NBIX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a gross profit of 800.70M and revenue of 814.50M. Therefore, the gross margin over that period was 98.3%.

OR - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Osisko Gold Royalties Ltd reported a gross profit of 87.28M and revenue of 101.41M. Therefore, the gross margin over that period was 86.1%.

NBIX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported an operating income of 193.40M and revenue of 814.50M, resulting in an operating margin of 23.7%.

OR - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Osisko Gold Royalties Ltd reported an operating income of 79.13M and revenue of 101.41M, resulting in an operating margin of 78.0%.

NBIX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a net income of 197.90M and revenue of 814.50M, resulting in a net margin of 24.3%.

OR - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Osisko Gold Royalties Ltd reported a net income of 72.56M and revenue of 101.41M, resulting in a net margin of 71.6%.


Frequently Asked Questions


NBIX and OR have a correlation of -0.03, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

OR has higher volatility (13.74%) compared to NBIX (8.08%). In terms of maximum drawdown, NBIX dropped -97.21% vs OR's -61.90%.

NBIX currently has the higher Sharpe Ratio (0.99 vs 0.22), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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