MSFT vs. TMO
MSFT (Microsoft Corporation) and TMO (Thermo Fisher Scientific Inc.) are both stocks. MSFT operates in Software - Infrastructure (Technology), while TMO operates in Diagnostics & Research (Healthcare). Over the past 10 years, MSFT returned 24.39%/yr vs 12.54%/yr for TMO. At a 0.34 correlation, their price movements are largely independent.
Performance
MSFT vs. TMO - Performance Comparison
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Returns By Period
The year-to-date returns for both stocks are quite close, with MSFT having a -18.85% return and TMO slightly lower at -18.92%. Over the past 10 years, MSFT has outperformed TMO with an annualized return of 24.39%, while TMO has yielded a comparatively lower 12.54% annualized return.
MSFT
- 1D
- 0.10%
- 1M
- -3.36%
- YTD
- -18.85%
- 6M
- -17.98%
- 1Y
- -17.75%
- 3Y*
- 6.16%
- 5Y*
- 9.56%
- 10Y*
- 24.39%
TMO
- 1D
- -1.33%
- 1M
- 5.23%
- YTD
- -18.92%
- 6M
- -17.84%
- 1Y
- 13.42%
- 3Y*
- -3.43%
- 5Y*
- 0.45%
- 10Y*
- 12.54%
MSFT vs. TMO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
MSFT Microsoft Corporation | -18.85% | 15.58% | 12.93% | 58.19% | -28.02% | 52.48% | 42.53% | 57.56% | 20.80% | 40.73% |
TMO Thermo Fisher Scientific Inc. | -18.92% | 11.78% | -1.72% | -3.36% | -17.29% | 43.54% | 43.72% | 45.55% | 18.21% | 35.03% |
Correlation
The correlation between MSFT and TMO is 0.15, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.15 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.18 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.36 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.44 |
Correlation (All Time) Calculated using the full available price history since Sep 1, 1987 | 0.34 |
The correlation between MSFT and TMO shifts across timeframes, from 0.15 (1 year) to 0.44 (10 years), reflecting how their relationship changes across market environments.
Fundamentals
MSFT:
$2.91T
TMO:
$175.06B
MSFT:
$16.79
TMO:
$18.22
MSFT:
23.27
TMO:
25.76
MSFT:
9.16
TMO:
3.91
MSFT:
7.02
TMO:
3.37
MSFT:
$318.27B
TMO:
$45.20B
MSFT:
$217.41B
TMO:
$17.81B
MSFT:
$200.96B
TMO:
$11.16B
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Return for Risk
MSFT vs. TMO — Risk / Return Rank
MSFT
TMO
MSFT vs. TMO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Microsoft Corporation (MSFT) and Thermo Fisher Scientific Inc. (TMO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| MSFT | TMO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.13 | ||
| Sortino ratioReturn per unit of downside risk | -1.71 | ||
| Omega ratioGain probability vs. loss probability | 0.89 | 1.10 | -0.21 |
| Calmar ratioReturn relative to maximum drawdown | -0.53 | 0.43 | -0.95 |
| Martin ratioReturn relative to average drawdown | -1.08 | 0.93 | -2.01 |
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Drawdowns
MSFT vs. TMO - Drawdown Comparison
The maximum MSFT drawdown since its inception was -69.38%, roughly equal to the maximum TMO drawdown of -71.16%. Use the drawdown chart below to compare losses from any high point for MSFT and TMO.
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Drawdown Indicators
| MSFT | TMO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -69.38% | -71.16% | +1.78% |
Max Drawdown (1Y)Largest decline over 1 year | -33.91% | -31.38% | -2.53% |
Max Drawdown (3Y)Largest decline over 3 years | -33.91% | -37.28% | +3.37% |
Max Drawdown (5Y)Largest decline over 5 years | -37.15% | -40.95% | +3.80% |
Max Drawdown (10Y)Largest decline over 10 years | -37.15% | -40.95% | +3.80% |
Current DrawdownCurrent decline from peak | -27.46% | -28.80% | +1.34% |
Average DrawdownAverage peak-to-trough decline | -21.78% | -18.11% | -3.67% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 16.48% | 14.43% | +2.05% |
Volatility
MSFT vs. TMO - Volatility Comparison
Microsoft Corporation (MSFT) and Thermo Fisher Scientific Inc. (TMO) have volatilities of 10.52% and 10.57%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| MSFT | TMO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 10.52% | 10.57% | -0.05% |
Volatility (6M)Calculated over the trailing 6-month period | 22.31% | 22.27% | +0.04% |
Volatility (1Y)Calculated over the trailing 1-year period | 25.42% | 31.48% | -6.06% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 26.66% | 27.20% | -0.54% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 27.06% | 26.38% | +0.68% |
Dividends
MSFT vs. TMO - Dividend Comparison
MSFT's dividend yield for the trailing twelve months is around 0.91%, more than TMO's 0.37% yield.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MSFT Microsoft Corporation | 0.91% | 0.70% | 0.73% | 0.74% | 1.06% | 0.68% | 0.94% | 1.20% | 1.69% | 1.86% | 2.37% | 2.33% |
TMO Thermo Fisher Scientific Inc. | 0.37% | 0.30% | 0.30% | 0.26% | 0.22% | 0.16% | 0.19% | 0.23% | 0.30% | 0.32% | 0.43% | 0.42% |
Financials
MSFT vs. TMO - Financials Comparison
This section allows you to compare key financial metrics between Microsoft Corporation and Thermo Fisher Scientific Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
MSFT vs. TMO - Profitability Comparison
MSFT - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Microsoft Corporation reported a gross profit of 56.06B and revenue of 82.89B. Therefore, the gross margin over that period was 67.6%.
TMO - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Thermo Fisher Scientific Inc. reported a gross profit of 4.48B and revenue of 11.01B. Therefore, the gross margin over that period was 40.7%.
MSFT - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Microsoft Corporation reported an operating income of 38.40B and revenue of 82.89B, resulting in an operating margin of 46.3%.
TMO - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Thermo Fisher Scientific Inc. reported an operating income of 1.86B and revenue of 11.01B, resulting in an operating margin of 16.9%.
MSFT - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Microsoft Corporation reported a net income of 31.78B and revenue of 82.89B, resulting in a net margin of 38.3%.
TMO - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Thermo Fisher Scientific Inc. reported a net income of 1.65B and revenue of 11.01B, resulting in a net margin of 15.0%.
Frequently Asked Questions
MSFT and TMO have a correlation of 0.15, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TMO has higher volatility (10.57%) compared to MSFT (10.52%). In terms of maximum drawdown, MSFT dropped -69.38% vs TMO's -71.16%.
TMO currently has the higher Sharpe Ratio (0.43 vs -0.70), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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