KNSA vs. SEI

Last updated Aug 1, 2026

KNSA (Kiniksa Pharmaceuticals, Ltd.) and SEI (Solaris Energy Infrastructure, Inc) are both stocks. KNSA operates in Biotechnology (Healthcare), while SEI operates in Oil & Gas Equipment & Services (Energy). Over the past 5 years, KNSA returned 37.13%/yr vs 47.96%/yr for SEI. Their 0.14 correlation means their historical movements had little consistent relationship.

Performance

KNSA vs. SEI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Kiniksa Pharmaceuticals, Ltd. (KNSA) and Solaris Energy Infrastructure, Inc (SEI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, KNSA achieves a 80.22% return, which is significantly higher than SEI's 12.30% return.

KNSA

• 1D: -4.94%
• 1M: 18.22%
• 6M: 69.26%
• YTD: 80.22%
• 1Y: 145.67%
• 3Y*: 57.85%
• 5Y*: 37.13%
• 10Y*: —
• ALL TIME*: 14.55%

SEI

• 1D: 0.25%
• 1M: -29.98%
• 6M: -6.46%
• YTD: 12.30%
• 1Y: 58.96%
• 3Y*: 73.99%
• 5Y*: 47.96%
• 10Y*: —
• ALL TIME*: 20.73%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
KNSA Kiniksa Pharmaceuticals, Ltd.	$68.75M	$54.52M	$46.86M
SEI Solaris Energy Infrastructure, Inc	$200.05M	$228.81M	$190.63M

KNSA vs. SEI - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
KNSA Kiniksa Pharmaceuticals, Ltd.	80.22%	108.54%	12.77%	17.09%	27.27%	-33.39%	59.76%	-60.63%	14.89%
SEI Solaris Energy Infrastructure, Inc	12.30%	62.29%	277.66%	-15.75%	57.46%	-15.55%	-38.09%	19.10%	-25.94%

Correlation

The correlation between KNSA and SEI is 0.03, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.03
Correlation (3Y) Balances recent behavior with more history.	0.15
Correlation (5Y) Shows whether the relationship held over a longer period.	0.15
Correlation (All Time) Calculated using the full available price history since May 24, 2018	0.14

The correlation between KNSA and SEI shifts across timeframes, from 0.03 (1 year) to 0.15 (3 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap KNSA : $5.67B SEI : $3.15B
EPS KNSA : $1.00 SEI : $0.97
PE Ratio KNSA : 74.38 SEI : 52.86
PS Ratio KNSA : 7.14 SEI : 3.54
PB Ratio KNSA : 9.48 SEI : 3.26
Total Revenue (TTM) KNSA : $840.85M SEI : $692.11M
Gross Profit (TTM) KNSA : $546.22M SEI : $235.28M
EBITDA (TTM) KNSA : $111.62M SEI : $249.65M

Return for Risk

KNSA vs. SEI — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

KNSA

KNSA Risk / Return Rank: 97
KNSA Sharpe Ratio Rank: 97
KNSA Sortino Ratio Rank: 97
KNSA Omega Ratio Rank: 96
KNSA Calmar Ratio Rank: 97
KNSA Martin Ratio Rank: 98

SEI

SEI Risk / Return Rank: 71
SEI Sharpe Ratio Rank: 70
SEI Sortino Ratio Rank: 70
SEI Omega Ratio Rank: 68
SEI Calmar Ratio Rank: 70
SEI Martin Ratio Rank: 78

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

KNSA vs. SEI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Kiniksa Pharmaceuticals, Ltd. (KNSA) and Solaris Energy Infrastructure, Inc (SEI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	KNSA	SEI	Difference
Sharpe ratio: Return per unit of total volatility	2.94	0.76	+2.18
Sortino ratio: Return per unit of downside risk	4.18	1.49	+2.68
Omega ratio: Gain probability vs. loss probability	1.52	1.18	+0.34
Calmar ratio: Return relative to maximum drawdown	6.94	1.24	+5.70
Martin ratio: Return relative to average drawdown	24.13	4.72	+19.41

KNSA vs. SEI - Sharpe Ratio Comparison

The current KNSA Sharpe Ratio is 2.94, which is higher than the SEI Sharpe Ratio of 0.76. The chart below compares the historical Sharpe Ratios of KNSA and SEI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

KNSA vs. SEI - Drawdown Comparison

The maximum KNSA drawdown since its inception was -83.06%, roughly equal to the maximum SEI drawdown of -79.49%. Use the drawdown chart below to compare losses from any high point for KNSA and SEI.

Drawdown Indicators

	KNSA	SEI	Difference
Max Drawdown Largest peak-to-trough decline	-83.06%	-79.49%	-3.57%
Max Drawdown (1Y) Largest decline over 1 year	-21.12%	-47.61%	+26.49%
Max Drawdown (3Y) Largest decline over 3 years	-34.14%	-55.37%	+21.23%
Max Drawdown (5Y) Largest decline over 5 years	-53.17%	-55.37%	+2.20%
Current Drawdown Current decline from peak	-8.13%	-37.97%	+29.84%
Average Drawdown Average peak-to-trough decline	-40.09%	-38.32%	-1.77%
Ulcer Index Depth and duration of drawdowns from previous peaks	6.06%	12.78%	-6.72%

Volatility

KNSA vs. SEI - Volatility Comparison

The current volatility for Kiniksa Pharmaceuticals, Ltd. (KNSA) is 26.47%, while Solaris Energy Infrastructure, Inc (SEI) has a volatility of 30.50%. This indicates that KNSA experiences smaller price fluctuations and is considered to be less risky than SEI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	KNSA	SEI	Difference
Volatility (1M) Calculated over the trailing 1-month period	26.47%	30.50%	-4.03%
Volatility (6M) Calculated over the trailing 6-month period	41.55%	57.43%	-15.88%
Volatility (1Y) Calculated over the trailing 1-year period	49.77%	77.63%	-27.86%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	54.77%	68.06%	-13.29%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	64.34%	62.88%	+1.46%

Dividends

KNSA vs. SEI - Dividend Comparison

KNSA has not paid dividends to shareholders, while SEI's dividend yield for the trailing twelve months is around 0.93%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018
KNSA Kiniksa Pharmaceuticals, Ltd.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
SEI Solaris Energy Infrastructure, Inc	0.93%	1.04%	1.67%	5.65%	4.23%	6.41%	5.16%	2.89%	0.83%

Financials

KNSA vs. SEI - Profitability Comparison

The chart below illustrates the profitability comparison between Kiniksa Pharmaceuticals, Ltd. and Solaris Energy Infrastructure, Inc over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

KNSA - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Kiniksa Pharmaceuticals, Ltd. reported a gross profit of 220.03M and revenue of 243.60M. Therefore, the gross margin over that period was 90.3%.

SEI - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Solaris Energy Infrastructure, Inc reported a gross profit of 72.72M and revenue of 196.24M. Therefore, the gross margin over that period was 37.1%.

KNSA - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Kiniksa Pharmaceuticals, Ltd. reported an operating income of 27.19M and revenue of 243.60M, resulting in an operating margin of 11.2%.

SEI - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Solaris Energy Infrastructure, Inc reported an operating income of 50.56M and revenue of 196.24M, resulting in an operating margin of 25.8%.

KNSA - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Kiniksa Pharmaceuticals, Ltd. reported a net income of 25.43M and revenue of 243.60M, resulting in a net margin of 10.4%.

SEI - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Solaris Energy Infrastructure, Inc reported a net income of 21.44M and revenue of 196.24M, resulting in a net margin of 10.9%.

Frequently Asked Questions

Can I hold both KNSA and SEI in my portfolio?

KNSA and SEI have a correlation of 0.03, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, KNSA or SEI?

SEI has higher volatility (30.50%) compared to KNSA (26.47%). In terms of maximum drawdown, KNSA dropped -83.06% vs SEI's -79.49%.

Which has better risk-adjusted returns?

KNSA currently has the higher Sharpe Ratio (2.94 vs 0.76), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.