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KNSA vs. BMRN
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

KNSA vs. BMRN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Kiniksa Pharmaceuticals, Ltd. (KNSA) and BioMarin Pharmaceutical Inc. (BMRN). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, KNSA achieves a 16.00% return, which is significantly higher than BMRN's -8.03% return.


KNSA

1D
1.98%
1M
-16.96%
YTD
16.00%
6M
17.89%
1Y
64.38%
3Y*
48.51%
5Y*
29.11%
10Y*

BMRN

1D
2.51%
1M
-1.44%
YTD
-8.03%
6M
0.64%
1Y
-3.75%
3Y*
-16.34%
5Y*
-6.84%
10Y*
-4.86%
*Multi-year figures are annualized to reflect compound growth (CAGR)

KNSA vs. BMRN - Yearly Performance Comparison


2026 (YTD)20252024202320222021202020192018
KNSA
Kiniksa Pharmaceuticals, Ltd.
16.00%108.54%12.77%17.09%27.27%-33.39%59.76%-60.63%44.27%
BMRN
BioMarin Pharmaceutical Inc.
-8.03%-9.58%-31.83%-6.83%17.14%0.75%3.71%-0.70%-3.55%

Correlation

The correlation between KNSA and BMRN is 0.25, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.25

Correlation (3Y)
Calculated over the trailing 3-year period

0.28

Correlation (5Y)
Calculated over the trailing 5-year period

0.35

Correlation (All Time)
Calculated using the full available price history since May 25, 2018

0.34

The correlation between KNSA and BMRN shifts across timeframes, from 0.25 (1 year) to 0.35 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

KNSA:

$3.94B

BMRN:

$10.80B

EPS

KNSA:

$0.92

BMRN:

$1.37

PE Ratio

KNSA:

51.96

BMRN:

39.85

PEG Ratio

KNSA:

0.50

BMRN:

2.39

PS Ratio

KNSA:

5.03

BMRN:

3.30

PB Ratio

KNSA:

6.51

BMRN:

1.74

Total Revenue (TTM)

KNSA:

$754.05M

BMRN:

$3.24B

Gross Profit (TTM)

KNSA:

$294.06M

BMRN:

$2.46B

EBITDA (TTM)

KNSA:

$101.06M

BMRN:

$439.56M

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Return for Risk

KNSA vs. BMRN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

KNSA
KNSA Risk / Return Rank: 8383
Overall Rank
KNSA Sharpe Ratio Rank: 8181
Sharpe Ratio Rank
KNSA Sortino Ratio Rank: 8181
Sortino Ratio Rank
KNSA Omega Ratio Rank: 7979
Omega Ratio Rank
KNSA Calmar Ratio Rank: 8383
Calmar Ratio Rank
KNSA Martin Ratio Rank: 8989
Martin Ratio Rank

BMRN
BMRN Risk / Return Rank: 3434
Overall Rank
BMRN Sharpe Ratio Rank: 3636
Sharpe Ratio Rank
BMRN Sortino Ratio Rank: 3232
Sortino Ratio Rank
BMRN Omega Ratio Rank: 3232
Omega Ratio Rank
BMRN Calmar Ratio Rank: 3535
Calmar Ratio Rank
BMRN Martin Ratio Rank: 3434
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

KNSA vs. BMRN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Kiniksa Pharmaceuticals, Ltd. (KNSA) and BioMarin Pharmaceutical Inc. (BMRN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


KNSABMRNDifference
Sharpe ratioReturn per unit of total volatility

+1.59

Sortino ratioReturn per unit of downside risk

+2.28

Omega ratioGain probability vs. loss probability

1.30

1.01

+0.29

Calmar ratioReturn relative to maximum drawdown

3.06

-0.17

+3.23

Martin ratioReturn relative to average drawdown

11.39

-0.35

+11.74

KNSA vs. BMRN - Sharpe Ratio Comparison

The current KNSA Sharpe Ratio is 1.48, which is higher than the BMRN Sharpe Ratio of -0.11. The chart below compares the historical Sharpe Ratios of KNSA and BMRN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Sharpe Ratios by Period


KNSABMRNDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.48

-0.11

+1.59

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

0.55

-0.21

+0.76

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

-0.14

Sharpe Ratio (All Time)

Calculated using the full available price history

0.19

0.11

+0.08

Drawdowns

KNSA vs. BMRN - Drawdown Comparison

The maximum KNSA drawdown since its inception was -83.06%, smaller than the maximum BMRN drawdown of -90.58%. Use the drawdown chart below to compare losses from any high point for KNSA and BMRN.


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Drawdown Indicators


KNSABMRNDifference

Max Drawdown

Largest peak-to-trough decline

-83.06%

-90.58%

+7.52%

Max Drawdown (1Y)

Largest decline over 1 year

-21.12%

-22.49%

+1.37%

Max Drawdown (3Y)

Largest decline over 3 years

-34.14%

-49.83%

+15.69%

Max Drawdown (5Y)

Largest decline over 5 years

-53.17%

-57.64%

+4.47%

Max Drawdown (10Y)

Largest decline over 10 years

-62.09%

Current Drawdown

Current decline from peak

-19.55%

-63.35%

+43.80%

Average Drawdown

Average peak-to-trough decline

-40.26%

-45.51%

+5.25%

Ulcer Index

Depth and duration of drawdowns from previous peaks

5.67%

10.84%

-5.17%

Volatility

KNSA vs. BMRN - Volatility Comparison

The current volatility for Kiniksa Pharmaceuticals, Ltd. (KNSA) is 10.38%, while BioMarin Pharmaceutical Inc. (BMRN) has a volatility of 15.30%. This indicates that KNSA experiences smaller price fluctuations and is considered to be less risky than BMRN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


KNSABMRNDifference

Volatility (1M)

Calculated over the trailing 1-month period

10.38%

15.30%

-4.92%

Volatility (6M)

Calculated over the trailing 6-month period

33.56%

27.79%

+5.77%

Volatility (1Y)

Calculated over the trailing 1-year period

43.77%

34.57%

+9.20%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

53.49%

32.87%

+20.62%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

63.66%

35.51%

+28.15%

Dividends

KNSA vs. BMRN - Dividend Comparison

Neither KNSA nor BMRN has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

KNSA vs. BMRN - Financials Comparison

This section allows you to compare key financial metrics between Kiniksa Pharmaceuticals, Ltd. and BioMarin Pharmaceutical Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00200.00M400.00M600.00M800.00M20222023202420252026
214.27M
766.21M
(KNSA) Total Revenue
(BMRN) Total Revenue
Values in USD except per share items

KNSA vs. BMRN - Profitability Comparison

The chart below illustrates the profitability comparison between Kiniksa Pharmaceuticals, Ltd. and BioMarin Pharmaceutical Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

0.0%20.0%40.0%60.0%80.0%202220232024202520260
74.6%
Portfolio components
KNSA - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Kiniksa Pharmaceuticals, Ltd. reported a gross profit of 0.00 and revenue of 214.27M. Therefore, the gross margin over that period was 0.0%.

BMRN - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, BioMarin Pharmaceutical Inc. reported a gross profit of 571.21M and revenue of 766.21M. Therefore, the gross margin over that period was 74.6%.

KNSA - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Kiniksa Pharmaceuticals, Ltd. reported an operating income of 29.27M and revenue of 214.27M, resulting in an operating margin of 13.7%.

BMRN - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, BioMarin Pharmaceutical Inc. reported an operating income of 129.64M and revenue of 766.21M, resulting in an operating margin of 16.9%.

KNSA - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Kiniksa Pharmaceuticals, Ltd. reported a net income of 22.59M and revenue of 214.27M, resulting in a net margin of 10.5%.

BMRN - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, BioMarin Pharmaceutical Inc. reported a net income of 105.53M and revenue of 766.21M, resulting in a net margin of 13.8%.


Frequently Asked Questions


KNSA and BMRN have a correlation of 0.25, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

BMRN has higher volatility (15.30%) compared to KNSA (10.38%). In terms of maximum drawdown, KNSA dropped -83.06% vs BMRN's -90.58%.

KNSA currently has the higher Sharpe Ratio (1.48 vs -0.11), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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